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The map label for this gene is mtlR [H]

Identifier: 209400358

GI number: 209400358

Start: 4619488

End: 4620075

Strand: Direct

Name: mtlR [H]

Synonym: ECH74115_4971

Alternate gene names: 209400358

Gene position: 4619488-4620075 (Clockwise)

Preceding gene: 209395785

Following gene: 209399195

Centisome position: 82.9

GC content: 51.36

Gene sequence:

>588_bases
ATGGTGGACCAGGCGCAGGACACCCTGCGCCCGAATAACAGATTGTCAGATATGCAGGCAACAATGGAACAAACCCAGGC
CTTTGAAAACCGTGTGCTTGAGCGTCTGAATGCTGGCAAAACCGTGCGAAGCTTTCTGATCACCGCCGTCGAGCTTTTGA
CCGAGGCGGTAAATCTTCTGGTGCTTCAGGTATTCCGCAAAGACGATTACGCGGTGAAGTATGCTGTAGAACCGTTACTC
GACGGCGACGGTCCGCTGGGCGATCTTTCTGTGCGTTTAAAACTCATTTACGGGTTGGGCGTCATTAACCGCCAGGAATA
CGAAGATGCGGAGCTGCTGATGGCATTGCGTGAAGAACTAAATCACGACGGCAACGAGTACGCCTTTACCGACGACGAGA
TCCTTGGACCCTTTGGGGAACTGCACTGCGTGGCGGCGTTACCACCGCCGCCACAGTTTGAACCAGCAGACTCCAGTTTG
TATGCAATGCAAATTCAGCGCTATCAACAGGCTGTGCGATCAACAATGGTCCTTTCACTGACTGAGCTGATTTCCAGAAT
CAGCTTAAAAAAAGCCTTTCAAAAGTAA

Upstream 100 bases:

>100_bases
CTGACAAAGGTCCGCAGGCGGCGCTGGCACAGATTTCCGATCTTGATGCCAACAGCGAGGTTGTATCCGAGGCGGTAACC
GCTTATAAAGCAATGCAATA

Downstream 100 bases:

>100_bases
GCAACGTCTGCTTACTGCCCCTCTACCTGCTTCGGCCGATAAAGCCGACGATAATACTCCAGACGTTGTAGATATAACGG
CACGCTTTCATCGGGTATTC

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLL
DGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK

Sequences:

>Translated_195_residues
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLL
DGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK
>Mature_195_residues
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLL
DGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=195, Percent_Identity=99.4871794871795, Blast_Score=396, Evalue=1e-112,
Organism=Escherichia coli, GI1789297, Length=105, Percent_Identity=36.1904761904762, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 22018; Mature: 22018

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLL
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREEL
HHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
NHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSLYAMQIQRYQQAVRSTMVLSL
CCCCCCCEECCHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TELISRISLKKAFQK
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLL
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREEL
HHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
NHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSLYAMQIQRYQQAVRSTMVLSL
CCCCCCCEECCHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TELISRISLKKAFQK
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]