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The map label for this gene is flu [H]

Identifier: 209399047

GI number: 209399047

Start: 1387736

End: 1390585

Strand: Direct

Name: flu [H]

Synonym: ECH74115_1395

Alternate gene names: 209399047

Gene position: 1387736-1390585 (Clockwise)

Preceding gene: 209400007

Following gene: 209399963

Centisome position: 24.91

GC content: 57.19

Gene sequence:

>2850_bases
ATGAAACGACATCTGAACACCAGCTACAGGCTGGTATGGAATCACATTACGGGCACCCTGGTGGTGGCCTCCGAACTGGC
CCGCTCACGGGGAAAACGCGCCGGTGTGGCGGTTGCGCTGTCTCTTGCTGCTGTCACATCAGTCCCGGCACTGGCTGCTG
ACAAGGTTGTACAGGCGGGAGAAACCGTGAACGATGGAACACTGACAAATCATGACAACCAGATTGTCTTCGGTACGGCC
AACGGAATGACCATCAGTACCGGGCTGGAACTGGGGCCGGACAGTGAAGAAAACACCGGTGGGCAATGGATACAGAATGG
CGGGATAGCCGGAAACACCACTGTCACCACAAATGGTCGTCAGGTCGTGCTGGAGGGGGGAACAGCCAGTGATACGGTTA
TTCGTGACGGCGGGGGACAGAGCCTGAACGGACTGGCGGTGAACACCACACTGAATAACAGAGGCGAGCAGTGGGTGCAT
GAGGGCGGGGTTGCCACCGGTACAATTATCAACCGCGACGGTTACCAGAGCGTTAAAAGTGGCGGGCTGGCAACAGGAAC
CATCATCAACACCGGCGCAGAAGGCGGCCCTGATTCTGACAACTCGTATACGGGTCAGAAGGTCCAGGGAACAGCAGAAT
CCACCACCATCAACAAAAATGGACGGCAGATTATCTTATTTTCCGGGCTAGCCCGTGACACTCTCATTTACGCAGGTGGT
GACCAGTCGGTACACGGAAGGGCCCTGAATACCACACTGAATGGCGGTTACCAATATGTGCACAGGGACGGACTTGCGCT
GAACACGGTAATTAACGAGGGGGGCTGGCAGGTTGTTAAGGCAGGTGGCGCTGCCGGTAACACCACCATAAATCAGAACG
GTGAACTGAGGGTACATGCCGGCGGGGAAGCCACTGCAGTCACCCAGAACACGGGCGGTGCACTGGTTACCAGTACTGCT
GCAACTGTCATCGGCACAAACCGTCTGGGGAATTTCACGGTGGAAAACGGTAAGGCTGACGGTGTTGTTCTGGAATCCGG
CGGTCGTCTGGATGTACTGGAGAGCCATTCAGCACAGAATACCCTAGTGGATGACGGCGGTACCCTGGCAGTGTCTGCCG
GCGGTAAGGCGACAAGTGTCACCATAACATCCGGTGGTGCCCTGATTGCAGACAGTGGTGCCACTGTTGAGGGGACCAAT
GCCAGCGGTAAGTTCAGTATTGATGGCACATCCGGTCAGGCCAGCGGCCTGCTGCTGGAAAATGGCGGCAGCTTTACGGT
TAATGCCGGGGGACAGGCTGGCAACACCACTGTCGGACATCGTGGAACACTGACGCTGGCTGCCGGGGGAAGTCTGAGTG
GCAGAACACAGCTCAGTAAAGGCGCCAGTATGGTACTGAATGGTGATGTGGTCAGTACCGGCGATATTGTTAACGCAGGG
GAGATTCGCTTTGATAATCAGACGACACCGAATGCCGCGCTGAGCCGTGCTGTTGCAAAAAGTAACTCCCCGGTAACGTT
CCATAAACTGACCACCACGAACCTCACCGGCCAGGGCGGCACCATCAATATGCGTGTTCGCCTTGATGGCAGCAATGCCT
CTGACCAGCTGGTGATTAATGGTGGTCAGGCAACCGGCAAAACCTGGCTTGCGTTTACAAATGTCGGAAACAGCAACCTC
GGGGTGGCAACCACCGGACAGGGTATCCGGGTTGTGGATGCACAGAATGGCGCCACCACAGAAGAAGGTGCGTTTGCCCT
GAGTCGCCCGCTTCAGGCCGGCGCCTTTAACTACACCCTGAACCGTGACAGCGATGAAGACTGGTACCTGCGCAGTGAAA
ATGCTTATCGTGCTGAAGTCCCCCTGTATACATCCATGTTGACACAGGCAATGGACTATGACCGGATTCTGGCAGGCTCC
CGCAGCCATCAGACCGGTGTAAACGGTGAAAATAACAGCGTCCGTCTCAGCATTCAGGGCGGTCATCTCGGTCACGATAA
CAACGGCGGTATTGCCCGTGGAGCCACGCCGGAAAGCAGCGGCAGCTATGGCTTCGTCCGTCTGGAGGGTGACCTGCTCA
GAACAGAGGTTGCCGGTATGTCTCTGACGACAGGGGTGTATGGTGCTGCAGGCCATTCTTCCGTTGATGTTAAGGATGAT
GACGGTTCCCGCGCCGGCACGGTCCGGGATGATGCCGGCAGTCTGGGCGGATACCTGAATCTGGTACACACATCCTCCGG
CCTGTGGGCTGACATTGTGGCCCAGGGAACCCGTCACAGCATGAAAGCGTCATCGGACAATAACGACTTCCGCGCCCGGG
GCTGGGGCTGGCTGGGCTCACTGGAAACCGGTCTGCCCTTCAGTATCACTGACAATCTGATGCTGGAGCCACAACTGCAG
TACACCTGGCAGGGACTCTCCCTGGATGACGGCCAGGATAACGCCGGTTATGTGAAGTTCGGGCATGGCAGTGCACAACA
TGTGCGTGCCGGTTTCCGTCTGGGCAGCCACAACGATATGACCTTTGGTGAAGGCACCTCATCCCGTGACACCCTGCGCG
ACAGTGCAAAACACAGTGTGAGTGAACTGCCGGTGAACTGGTGGGTACAGCCTTCTGTTATCCGCACCTTCAGCTCCCGG
GGTGACATGAGCATGGGGACAGCCGCAGCCGGCAGTAACATGACGTTCTCACCGTCCCGGAATGGCACGTCACTGGACCT
GCAGGCCGGACTGGAAGCCCGTATCCGGGAAAATATCACCCTGGGCGTTCAGGCCGGTTATGCCCACAGCGTCAGCGGCA
GCAGCGCTGAAGGCTATAACGGTCAGGCTACGCTGAATATGACTTTCTGA

Upstream 100 bases:

>100_bases
CCGGGACGTATCGCTGTGCCCGATAACTCTGTTTTGTACCTGCCGGTATCCACTTTTGTGGGTACCGGCTTTTTTATTCA
CCCTCTGTAAGGAAAAGCTG

Downstream 100 bases:

>100_bases
TTATACGGTATCCCGGAAATACGATTTCAGGAAAATTCATGCAGTAATGGGAAAGGACGCTCATTGCTGTTCACCGCAGT
TCTGAATTATTGAATTTATA

Product: pertactin family protein

Products: NA

Alternate protein names: AG43; Fluffing protein [H]

Number of amino acids: Translated: 949; Mature: 949

Protein sequence:

>949_residues
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAGETVNDGTLTNHDNQIVFGTA
NGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGRQVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVH
EGGVATGTIINRDGYQSVKSGGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHAGGEATAVTQNTGGALVTSTA
ATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQNTLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTN
ASGKFSIDGTSGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNL
GVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGS
RSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQ
YTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSR
GDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF

Sequences:

>Translated_949_residues
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAGETVNDGTLTNHDNQIVFGTA
NGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGRQVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVH
EGGVATGTIINRDGYQSVKSGGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHAGGEATAVTQNTGGALVTSTA
ATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQNTLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTN
ASGKFSIDGTSGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNL
GVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGS
RSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQ
YTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSR
GDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF
>Mature_949_residues
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAGETVNDGTLTNHDNQIVFGTA
NGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGRQVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVH
EGGVATGTIINRDGYQSVKSGGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHAGGEATAVTQNTGGALVTSTA
ATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQNTLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTN
ASGKFSIDGTSGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNL
GVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGS
RSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQ
YTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSR
GDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF

Specific function: Controls colony form variation and autoaggregation. May function as an adhesin [H]

COG id: COG3468

COG function: function code MU; Type V secretory pathway, adhesin AidA

Gene ontology:

Cell location: Antigen 43 beta chain:Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

Organism=Escherichia coli, GI48994897, Length=1042, Percent_Identity=68.426103646833, Blast_Score=1317, Evalue=0.0,
Organism=Escherichia coli, GI87082145, Length=413, Percent_Identity=34.8668280871671, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1787954, Length=190, Percent_Identity=38.9473684210526, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR006315
- InterPro:   IPR012332
- InterPro:   IPR011050 [H]

Pfam domain/function: PF03797 Autotransporter [H]

EC number: NA

Molecular weight: Translated: 97816; Mature: 97816

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAG
CCCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHCC
ETVNDGTLTNHDNQIVFGTANGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGR
CCCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCEEEECCC
QVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVHEGGVATGTIINRDGYQSVKS
EEEEECCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCHHHHHC
GGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
CCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCEEEEECC
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHA
CCCCCCEEEEEEECCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCEEEEE
GGEATAVTQNTGGALVTSTAATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQN
CCCEEEEEECCCCEEEEECEEEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCC
TLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTNASGKFSIDGTSGQASGLLLE
CEEECCCEEEEECCCCEEEEEEECCCEEEECCCCEEECCCCCCEEEEECCCCCCCEEEEE
NGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCEEECCCEEECC
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVIN
EEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEEEEECCCCCCCEEEEE
GGQATGKTWLAFTNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTL
CCCCCCCEEEEEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEE
NRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQG
CCCCCCCCEEECCCCEEEECCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEEEC
GHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
CCCCCCCCCCEECCCCCCCCCCEEEEEEECCEEEEECCCCEEECCCCCCCCCCEEEEECC
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGS
CCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCCCCCCCCCCCCCEEEECCEEECC
LETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDM
CCCCCCEEECCCEEECCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHEEECCCCCC
TFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSR
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEECCCC
NGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF
CCCEEEEECCCCEEECCCEEEEEECCEEECCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAG
CCCCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHCC
ETVNDGTLTNHDNQIVFGTANGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGR
CCCCCCEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCEEEECCC
QVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVHEGGVATGTIINRDGYQSVKS
EEEEECCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCHHHHHC
GGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
CCEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCEEEEECC
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHA
CCCCCCEEEEEEECCCEEEEECCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCEEEEE
GGEATAVTQNTGGALVTSTAATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQN
CCCEEEEEECCCCEEEEECEEEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCC
TLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTNASGKFSIDGTSGQASGLLLE
CEEECCCEEEEECCCCEEEEEEECCCEEEECCCCEEECCCCCCEEEEECCCCCCCEEEEE
NGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
CCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCEEECCCEEECC
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVIN
EEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEEEEEECCCCCCCEEEEE
GGQATGKTWLAFTNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTL
CCCCCCCEEEEEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEE
NRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQG
CCCCCCCCEEECCCCEEEECCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEEEC
GHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
CCCCCCCCCCEECCCCCCCCCCEEEEEEECCEEEEECCCCEEECCCCCCCCCCEEEEECC
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGS
CCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCCCCCCCCCCCCCEEEECCEEECC
LETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDM
CCCCCCEEECCCEEECCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHEEECCCCCC
TFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSR
CCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEECCCC
NGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF
CCCEEEEECCCCEEECCCEEEEEECCEEECCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 2661530; 9298646; 9103983 [H]