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The map label for this gene is wzzB [H]

Identifier: 209399038

GI number: 209399038

Start: 2734222

End: 2735199

Strand: Reverse

Name: wzzB [H]

Synonym: ECH74115_2960

Alternate gene names: 209399038

Gene position: 2735199-2734222 (Counterclockwise)

Preceding gene: 209398959

Following gene: 209398834

Centisome position: 49.09

GC content: 46.01

Gene sequence:

>978_bases
ATGAGAGTAGAAAATAATAATGTTTCTGGGCAAAACCATGACCCGGAACAGATTGATTTGATTGATTTACTAGTGCAGTT
GTGGCGTGGCAAGATGACAATCATCATTTCCGTCATTGTGGCTATTGCTCTGGCTATTGGTTATTTGGCAGTAGCGAAGG
AGAAATGGACGTCAACAGCAATTATCACTCAGCCCGACGTGGGGCAAATTGCTGGCTATAACAATGCCATGAATGTTATC
TATGGTCAGGCTGCACCGAAAGTATCGGATTTGCAGGAGACGTTGATTGGTCGCTTCAGTTCTGCCTTCTCAGCATTAGC
AGAAACGCTGGATAATCAGGAAGAACCAGAAAAACTTACCATCGAATCTTCTGTTAAGAACCAGCAATTACCATTGACTG
TTTCTTATGTTGGGCAAACTGCAGAGGGAGCACAAATGAAGTTGGCCCAATACATTCAGCAAGTTGATGATAAAGTGAAT
CAAGAGCTAGAAAAGGATCTCAAAGACAACATTGCTCTGGGACGGAAAAACTTGCAGGACTCTTTAAGAACGCAGGAAGT
AGTTGCGCAGGAGCAGAAAGAGCTGCGTATCCGTCAGATTCAGGAAGCGTTGCAGTATGCGAATCAGGCGCAGGTGGCAA
AGCCACAGGTTCAGCAGACTGAAGATGTGACGCAAGATACGTTGTTCCTTTTGGGGAGCGAAGCGCTGGAGTCGATGATT
AAGCATGAGGCGACCCGTCCGTTGGTGTTCTCACCAAACTACTATCAGACACGTCAAAACCTGTTGGATATTGAAAACTT
AAAGGTTGATGATCTTGATATTCATGCTTACCGCTATGTAATGAAACCGACGTTACCTATTCGTCGCGATAGTCCGAAAA
AGGCAATCACCTTGATTCTGGCGGTGCTGCTGGGCGGCATGGTTGGCGCGGGGATTGTGCTGGGGCGTAACGCTCTGCGT
AATTACAACGCGAAGTAA

Upstream 100 bases:

>100_bases
CTCCGCAATAATTCATTATTTTTATCACTTATCCTATAGCATTCACAGGGATTATCGCTAAACTATGCGGACTTGGAAAT
TTCCGTCAGTTAGGGTAATG

Downstream 100 bases:

>100_bases
TCTTTTCGGTTTTAAAGAAAAAGGGCAGGGTGGTGACACCTTGCCCGTTTTTTTTGCCGGATGCGACAACAATATCGCAT
CCGCTTACCCCGCAACTCAC

Product: chain length determinant protein

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVI
YGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIESSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALR
NYNAK

Sequences:

>Translated_325_residues
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVI
YGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIESSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALR
NYNAK
>Mature_325_residues
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVI
YGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIESSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALR
NYNAK

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules [H]

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=97.239263803681, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI87082332, Length=341, Percent_Identity=25.5131964809384, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786802, Length=350, Percent_Identity=27.4285714285714, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 36282; Mature: 36282

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IITQPDVGQIAGYNNAMNVIYGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLT
EEECCCCHHHCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IESSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVNQELEKDLKDNIALGRKNLQD
EHHHCCCCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLIL
HHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IITQPDVGQIAGYNNAMNVIYGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLT
EEECCCCHHHCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
IESSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVNQELEKDLKDNIALGRKNLQD
EHHHCCCCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLIL
HHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]