Definition Escherichia coli O157:H7 str. EC4115, complete genome.
Accession NC_011353
Length 5,572,075

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The map label for this gene is ycgR [H]

Identifier: 209398957

GI number: 209398957

Start: 1621988

End: 1622143

Strand: Reverse

Name: ycgR [H]

Synonym: ECH74115_1681

Alternate gene names: 209398957

Gene position: 1622143-1621988 (Counterclockwise)

Preceding gene: 209396595

Following gene: 209397773

Centisome position: 29.11

GC content: 57.05

Gene sequence:

>156_bases
GTGGGCGCTCAGCGGCGCAAGAATGAAACCATCACCACTCCCCGTCTGAGCTTCCGTTTTCTTAACGTCAGCCCGACGGT
GGAGCGGCAATTACAGCGGATTATTTTCTCTCTCGAGCGGGAAGCCCGGGAGAAAGCGGACAAAGTACGCGACTGA

Upstream 100 bases:

>100_bases
GCGGTTCTTATGGTGCCTCGGCCCAGACGGCAACGGCTGTTATCAACATGCAAAATACCGATATTACGGTTGATCGTAAT
GGCAGTCTGGCGCTGGGTTT

Downstream 100 bases:

>100_bases
TTTACATCGCGTCCAGTGCCTGCTCAAGTTTGTAGATATAGCGCGGAGCCTGCGGCGCAGGATGATTTCGCGCTACGTGA
TCGAGGAACTCGTCAGCATC

Product: YcgR family protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR [H]

Number of amino acids: Translated: 51; Mature: 50

Protein sequence:

>51_residues
MGAQRRKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD

Sequences:

>Translated_51_residues
MGAQRRKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD
>Mature_50_residues
GAQRRKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. When bound to c-di-GMP it binds to elements of the flagellar motor (MotA (PubMed:20303158) and/or FliG and FliM (PubMed:20346

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI1787443, Length=45, Percent_Identity=100, Blast_Score=92, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009875
- InterPro:   IPR009926 [H]

Pfam domain/function: PF07238 PilZ; PF07317 YcgR [H]

EC number: NA

Molecular weight: Translated: 6089; Mature: 5958

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAQRRKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GAQRRKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]