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The map label for this gene is orn [H]

Identifier: 209398620

GI number: 209398620

Start: 5320529

End: 5321074

Strand: Direct

Name: orn [H]

Synonym: ECH74115_5678

Alternate gene names: 209398620

Gene position: 5320529-5321074 (Clockwise)

Preceding gene: 209396517

Following gene: 209398092

Centisome position: 95.49

GC content: 53.66

Gene sequence:

>546_bases
ATGAGTGCCAATGAAAACAACCTGATTTGGATCGATCTTGAGATGACCGGTCTGGATCCCGAGCGCGATCGCATTATTGA
GATTGCCACGCTGGTGACCGATGCCAATCTGAATATTCTGGCAGAAGGGCCGACCATTGCAGTACATCAGTCCGATGAAC
AGCTGGCGCTGATGGATGGCTGGAACGTGCGCACCCATACCGCCAGCGGGCTGGTGGAGCGCGTGAAAGCGAGCACGATG
GGCGATCGTGAAGCTGAACTGGCAACGCTCGAATTTTTAAAACAGTGGGTGCCTGCGGGTAAATCGCCGATTTGCGGTAA
CAGCATCGGTCAGGATCGTCGCTTCCTGTTTAAATACATGCCGGAGCTGGAAGCCTACTTCCACTACCGTTATCTCGATG
TCAGCACCCTGAAAGAGCTGGCGCGCCGCTGGAAGCCGGAAATTCTTGATGGTTTTACCAAACAGGGGACGCATCAGGCG
ATGGATGATATCCGTGAATCGGTGGCGGAGCTGGCTTACTACCGCGAGCATTTTATCAAGCTGTAA

Upstream 100 bases:

>100_bases
ACTCAATCGTACTGACTCCTGGTCGCCCCTGATGGGCAAAACATCTATGATACACGCAATTGTGGATCAATATAGTCACT
GTGAATGGGTGGAAAATAGC

Downstream 100 bases:

>100_bases
AATTTTTGCTGGTCACGTAAGCGCCGGAATCCACTTGCGGCGGCGTGATTTTGACGCTAAATTGAACGTCTTGCTGATAA
TTTCAGCACTTGAGATAAAA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDGWNVRTHTASGLVERVKASTM
GDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
MDDIRESVAELAYYREHFIKL

Sequences:

>Translated_181_residues
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDGWNVRTHTASGLVERVKASTM
GDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
MDDIRESVAELAYYREHFIKL
>Mature_180_residues
SANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDGWNVRTHTASGLVERVKASTMG
DREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAM
DDIRESVAELAYYREHFIKL

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=183, Percent_Identity=48.0874316939891, Blast_Score=181, Evalue=4e-46,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=99.4475138121547, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17557752, Length=177, Percent_Identity=49.7175141242938, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=35.1648351648352, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21355135, Length=177, Percent_Identity=45.7627118644068, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20758; Mature: 20627

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDG
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEEECCCCEEEEECC
WNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYM
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
SANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDG
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEEECCCCEEEEECC
WNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYM
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA