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The map label for this gene is surE [H]

Identifier: 209398515

GI number: 209398515

Start: 3694433

End: 3695194

Strand: Reverse

Name: surE [H]

Synonym: ECH74115_3995

Alternate gene names: 209398515

Gene position: 3695194-3694433 (Counterclockwise)

Preceding gene: 209398920

Following gene: 209399278

Centisome position: 66.32

GC content: 54.72

Gene sequence:

>762_bases
ATGCGCATATTGCTGAGTAATGATGACGGGGTACATGCACCCGGTATACAAACGCTGGCGAAAGCCTTGCGTGAGTTTGC
TGACGTTCAGGTGGTCGCCCCCGATCGTAACCGCAGCGGCGCTTCAAATTCTCTGACACTGGAATCCTCCCTGCGCACGT
TTACCTTTGAAAATGGTGATATTGCTGTGCAAATGGGAACCCCGACCGATTGCGTCTATCTTGGCGTGAATGCTCTGATG
CGTCCGCGCCCGGACATTGTTGTGTCCGGAATTAACGCCGGGCCGAATCTGGGGGATGATGTTATTTATTCCGGTACGGT
AGCCGCCGCGATGGAAGGCCGTCATTTAGGTTTTCCGGCGCTTGCCGTCTCGCTTGACGGGCATAAACATTACGACACTG
CCGCGGCGGTAACCTGTTCAATTTTGCGCGCACTGTGTAAAGAGCCGCTGCGCACCGGGCGTATTCTTAATATTAATGTT
CCGGATTTACCCTTGGATCAAATCAAAGGTATTCGCGTGACGCGCTGCGGTACACGACATCCGGCAGATCAGGTGATCCC
GCAGCAAGATCCGCGCGGCAATACGCTGTACTGGATTGGCCCGCCGGGCGGTAAATGTGATGCCGGTCCGGGGACCGATT
TTGCTGCGGTAGATGAGGGCTATGTCTCCATCACGCCGCTGCATGTGGATTTAACTGCGCATAGCGCGCAAGATGTGGTT
TCAGACTGGTTAAACAGCGTGGGAGTTGGCACGCAATGGTAA

Upstream 100 bases:

>100_bases
AATTGGTGGGATGACGTCACCGTAGAAATCCGTTTCTGGCTTCCGGCGGGTAGTTTTGCAACCAGCGTTGTCAGGGAACT
TATCAACACAACAGGTGATT

Downstream 100 bases:

>100_bases
GCAGACGCGTACAAGCACTTCTGGATCAATTACGTGCGCAAGGTATTCAGGATGAGCAGGTGCTGAATGCACTTGCCGCC
GTGCCGCGTGAAAAATTCGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
SDWLNSVGVGTQW

Sequences:

>Translated_253_residues
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
SDWLNSVGVGTQW
>Mature_253_residues
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
SDWLNSVGVGTQW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=100, Blast_Score=517, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002828 [H]

Pfam domain/function: PF01975 SurE [H]

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11 [H]

Molecular weight: Translated: 26901; Mature: 26901

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGD
CEEEEECCCCCCCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCEEEEEECCC
IAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRH
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEECCCCC
PADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
CHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEEECCCHHHHH
SDWLNSVGVGTQW
HHHHHHCCCCCCC
>Mature Secondary Structure
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGD
CEEEEECCCCCCCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCCEEEEEECCC
IAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEEECCCCCEEEECHHHHCCCCCCEEEECCCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRH
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEECCCCC
PADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
CHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCEEEEEEEEEEEECCCHHHHH
SDWLNSVGVGTQW
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA