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The map label for this gene is xylR

Identifier: 209398178

GI number: 209398178

Start: 4584254

End: 4585432

Strand: Direct

Name: xylR

Synonym: ECH74115_4945

Alternate gene names: 209398178

Gene position: 4584254-4585432 (Clockwise)

Preceding gene: 209398987

Following gene: 209399658

Centisome position: 82.27

GC content: 48.77

Gene sequence:

>1179_bases
ATGTTTACTAAACGTCACCGCATCACATTACTGTTCAATGCCAATAAAGCCTATGACCGGCAGGTAGTAGAAGGCGTAGG
GGAATATTTACAGGCGTCACAATCGGAATGGGATATTTTCATTGAAGAAGATTTCCGCGCCCGCATTGATAAAATCAAGG
ACTGGTTAGGAGATGGCGTCATTGCCGACTTCGACGACAAACAGATCGAGCAAGCGCTGGCTGATGTCGACGTCCCCATT
GTTGGGGTTGGCGGCTCGTATCACCTTGCAGAAAGTTACCCACCCGTTCATTACATTGCCACCGATAACTATGCGCTGGT
TGAAAGCGCATTTTTGCATTTAAAAGAGAAAGGCGTTAACCGCTTTGCTTTTTATGGTCTTCCGGAATCAAGCGGCAAAC
GTTGGGCCACTGAACGCGAATATGCATTTCGTCAGCTTGTCGCCGAAGAAAAGTATCGCGGAGTGGTTTATCAGGGGTTA
GAAACCGCACCAGAGAACTGGCAACACGCGCAAAATCGGCTGGCAGACTGGCTACAAACACTGCCACCGCAAACCGGGAT
TATTGCCGTTACTGACGCCCGGGCGCGGCATATTCTGCAAGTATGTGAACATCTACACATTCCCGTACCGGAAAAATTAT
GCGTGATTGGCATCGATAACGAAGAACTGACCCGCTATCTGTCGCGTGTCGCCCTTTCTTCGGTCGCTCAGGGCGCGCGG
CAAATGGGCTATCAGGCGGCAAAACTGTTGCATCGATTATTAGATAAAGAAGAAATGCCGCTACAGCGGATTTTGGTCCC
TCCAGTTCGCGTCATTGAACGGCGCTCAACAGATTACCGTTCGCTGACCGATCCCGCCGTTATTCAGGCCATGCATTACA
TTCGTAATCACGCCTGTAAAGGGATTAAAGTGGATCAGGTACTCGATGCGGTCGGGATCTCGCGCTCCAATCTTGAGAAG
CGTTTTAAAGAAGAGGTGGGTGAAACCATCCATGCCATGATTCATGCTGAGAAGCTGGAGAAAGCGCGCAGTCTGCTGAT
TTCAACCACCTTGTCGATCAATGAGATATCGCAAATGTGCGGTTATCCATCGCTGCAATATTTCTACTCTGTTTTTAAAA
AAGCATATGACACGACGCCAAAAGAGTATCGCGATGTAAATAGCGAGGTCATGTTGTAG

Upstream 100 bases:

>100_bases
CCGCAACCAAACGCCGTTCTTGATTTTGATAAAAATTTTCTCAAAGCCGGTAACGTATTACCGGTTTTGAGTTTTTGCAT
GATTCAGCAGGAAAAGAACC

Downstream 100 bases:

>100_bases
CGATGATGAGAATTGTCGGCGTCGCATCAGGTAACTCAGCACAACCACCTGATGCGATCAAAAGCCTTATCCGACCGACA
AGTCGGATAAGGCTCGAGGA

Product: xylose operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPI
VGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEK
RFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML

Sequences:

>Translated_392_residues
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPI
VGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEK
RFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
>Mature_392_residues
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPI
VGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEK
RFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML

Specific function: Regulatory protein for the xylBAFGHR operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789993, Length=392, Percent_Identity=100, Blast_Score=815, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLR_ECO57 (P0ACI5)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B86032
- PIR:   D91185
- RefSeq:   NP_290154.1
- RefSeq:   NP_312479.1
- ProteinModelPortal:   P0ACI5
- SMR:   P0ACI5
- EnsemblBacteria:   EBESCT00000024714
- EnsemblBacteria:   EBESCT00000057020
- GeneID:   915610
- GeneID:   961040
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4994
- KEGG:   ecs:ECs4452
- GeneTree:   EBGT00050000011175
- HOGENOM:   HBG296742
- OMA:   ICGYPSL
- ProtClustDB:   CLSK880726
- BioCyc:   ECOL83334:ECS4452-MONOMER
- GO:   GO:0005622
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF00165 HTH_AraC; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 44870; Mature: 44870

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGV
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCC
IADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVN
EECCCHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCC
RFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
CCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACK
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
GIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMC
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
CCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGV
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCC
IADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVN
EECCCHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCC
RFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
CCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACK
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
GIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMC
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
CCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796