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The map label for this gene is dmsB [H]

Identifier: 209397819

GI number: 209397819

Start: 3466931

End: 3467560

Strand: Reverse

Name: dmsB [H]

Synonym: ECH74115_3746

Alternate gene names: 209397819

Gene position: 3467560-3466931 (Counterclockwise)

Preceding gene: 209395905

Following gene: 209397088

Centisome position: 62.23

GC content: 49.84

Gene sequence:

>630_bases
ATGAGCCAATTTAAAGAATTTGCATCTGTCAGCGACAAACAATTAGGGTTCTTTATTGACTCTTCGCGTTGTTCGGGCTG
TAAAGCGTGTCAGGTGGCCTGTAAAGACAAAAACAACCTTGAGGTTGGGCGACGTTTTCGCCGCGTGTATGAAGTGAACG
GAGGTGGCTTCATCGCCACTGGAGAGGGCGGTGTGAGTCATAATGTCTTTGCTTATACCCTTTCTGTTTCCTGTAACCAT
TGCGCGGATCCGATCTGTACCAAAAATTGCCCGACGATGGCGATGCATAAGCGTCCCGGAGACGGTATTGTGCGCGTGAA
TACTGATAAGTGCGTCGGTTGCGGTTACTGCGCCTGGTCCTGTCCTTACGGCGCACCACAAATGAATGAGCAGACCGGGC
AGATGTCGAAATGCGATTTCTGTATTGATCTGCAAGCTAAAGGAGAACAACCCATTTGCGTGGCAACGTGCCCGTTGGGG
GCGATTAAGTTCGGCCCTATTGATGAGTTGCGTGAAAAGTATGGCGATGTCAGTGATGTGAAAGGTTTACCTGATTCGTC
GATTACGCAGCCAAATCTGGTGATTAAACCGCATCAGGGCGCGGAAAAGGAGGCGTCACATCATGCATGA

Upstream 100 bases:

>100_bases
TCGATCGCGGAGGCTGTGCCAATGTACTGAGTTCGACCCGCATTACGGCGCTGGCGAAAGGGAATTCGCATCAAACAATG
CTGGTGGAGGTTGAGAAAGC

Downstream 100 bases:

>100_bases
ATTACCGTTAATGGCTTTTACGCTGTTGTTACAGGCATCGGTCGGTATGACGTTGTGGCTGGCGTTTCTTCATCGTCATA
TTTTAATCACCTCCAGCGCC

Product: dimethylsulfoxide reductase, chain B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIATGEGGVSHNVFAYTLSVSCNH
CADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWSCPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLG
AIKFGPIDELREKYGDVSDVKGLPDSSITQPNLVIKPHQGAEKEASHHA

Sequences:

>Translated_209_residues
MSQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIATGEGGVSHNVFAYTLSVSCNH
CADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWSCPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLG
AIKFGPIDELREKYGDVSDVKGLPDSSITQPNLVIKPHQGAEKEASHHA
>Mature_208_residues
SQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIATGEGGVSHNVFAYTLSVSCNHC
ADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWSCPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLGA
IKFGPIDELREKYGDVSDVKGLPDSSITQPNLVIKPHQGAEKEASHHA

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=190, Percent_Identity=57.8947368421053, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1787872, Length=186, Percent_Identity=57.5268817204301, Blast_Score=217, Evalue=5e-58,
Organism=Escherichia coli, GI1787749, Length=178, Percent_Identity=33.7078651685393, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790326, Length=166, Percent_Identity=33.7349397590361, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789370, Length=174, Percent_Identity=35.0574712643678, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367345, Length=163, Percent_Identity=36.1963190184049, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI226510944, Length=153, Percent_Identity=37.2549019607843, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787740, Length=101, Percent_Identity=37.6237623762376, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787478, Length=98, Percent_Identity=37.7551020408163, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082179, Length=159, Percent_Identity=27.6729559748428, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787963, Length=146, Percent_Identity=29.4520547945205, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI87082180, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367245, Length=159, Percent_Identity=26.4150943396226, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788811, Length=159, Percent_Identity=27.0440251572327, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22598; Mature: 22467

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
10.0 %Cys+Met (Translated Protein)
7.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIAT
CCHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCEEEEE
GEGGVSHNVFAYTLSVSCNHCADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWS
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEECCCEECC
CPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLGAIKFGPIDELREKYGDVSDV
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEECCCHHHHHHHHCCHHHC
KGLPDSSITQPNLVIKPHQGAEKEASHHA
CCCCCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIAT
CHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCEEEEE
GEGGVSHNVFAYTLSVSCNHCADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWS
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEECCCEECC
CPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLGAIKFGPIDELREKYGDVSDV
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEECCCHHHHHHHHCCHHHC
KGLPDSSITQPNLVIKPHQGAEKEASHHA
CCCCCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]