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The map label for this gene is mglC [H]

Identifier: 209397480

GI number: 209397480

Start: 3013099

End: 3014109

Strand: Reverse

Name: mglC [H]

Synonym: ECH74115_3281

Alternate gene names: 209397480

Gene position: 3014109-3013099 (Counterclockwise)

Preceding gene: 209397905

Following gene: 209398712

Centisome position: 54.09

GC content: 50.54

Gene sequence:

>1011_bases
ATGAGTGCGTTAAATAAGAAAAGTTTTCTTACTTACCTGAAAGAGGGCGGTATTTACGTCGTTCTTTTAGTTTTGCTTGC
GATTATTATTTTCCAGGCCCCAACATTTTTAAGTCTGTTGAACTTAAGTAATATTCTCACCCAGTCATCGGTGCGTATTA
TTATCGCGCTCGGTGTGGCAGGGTTAATTGTCACCCAGGGGACCGACCTTTCTGCGGGGCGTCAAGTAGGGCTGGCGGCA
GTGGTGGCAGCGACATTATTGCAGTCCATGGATAACGCCAACAAAGTGTTCCCGGAAATGGCGACGATGCCGATTGCGCT
GGTTATTCTGATTGTCTGTGCCATTGGTGCGGTGATCGGTTTGATCAACGGTCTGATTATCGCTTATCTCAACGTGACGC
CGTTCATTACCACGCTCGGCACGATGATCATCGTCTATGGCATCAACTCGCTTTATTACGACTTTGTCGGGGCGTCGCCA
ATTTCTGGTTTTGACAGTGGCTTCTCTACCTTTGCTCAGGGCTTTGTCGCGCTGGGGAGTTTCCGTCTCTCTTACATCAC
CTTCTACGCGTTGATTGCGGTGGCGTTCGTCTGGGTGTTGTGGAACAAAACCCGCTTCGGTAAGAACATTTTTGCCATTG
GCGGTAACCCGGAAGCGGCAAAAGTATCTGGTGTCAACGTCGGCCTGAACCTGCTGATGATCTACGCGTTGTCTGGCGTG
TTCTATGCCTTTGGCGGGATGTTAGAAGCCGGACGTATCGGCTCTGCCACCAACAACCTCGGCTTTATGTATGAACTGGA
TGCTATCGCGGCGTGCGTGGTAGGCGGTGTATCGTTCAGCGGCGGTGTGGGGACGGTGATTGGCGTGGTGACCGGGGTAA
TTATTTTTACCGTCATCAACTATGGCCTGACGTACATCGGCGTAAACCCATACTGGCAGTACATCATCAAAGGGGCGATT
ATTATCTTCGCCGTAGCGCTGGATTCACTGAAGTACGCGCGTAAGAAGTGA

Upstream 100 bases:

>100_bases
GAGCAATGGCCTCGTTTCCGGAATTGTCGATACAAAAACAACAACGCAAAACGAAATTCTACGTCTTGCGTCTTTGCACC
TTTAAGATTAGGGGCTTCCC

Downstream 100 bases:

>100_bases
AATGATTGTGGTCCGCATTCGGTCATAAACGCACATAACATCATGATCTGTGTGGTTTTGTAGGCCGGATAAGGCGTTCA
CGCCGCATCCGGCGACAGGA

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK

Sequences:

>Translated_336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK
>Mature_335_residues
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAV
VAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPI
SGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGVF
YAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAII
IFAVALDSLKYARKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=99.7023809523809, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=323, Percent_Identity=34.6749226006192, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789992, Length=376, Percent_Identity=30.8510638297872, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790524, Length=332, Percent_Identity=33.433734939759, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788896, Length=332, Percent_Identity=32.2289156626506, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI145693152, Length=331, Percent_Identity=30.2114803625378, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787794, Length=304, Percent_Identity=31.9078947368421, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787793, Length=307, Percent_Identity=29.6416938110749, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693214, Length=269, Percent_Identity=31.5985130111524, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35507; Mature: 35375

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHH
GLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSGFSTFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
HCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHH
GLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSGFSTFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
HCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1719366; 9278503 [H]