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The map label for this gene is fabZ [H]

Identifier: 209397474

GI number: 209397474

Start: 1298890

End: 1299438

Strand: Direct

Name: fabZ [H]

Synonym: ECH74115_1285

Alternate gene names: 209397474

Gene position: 1298890-1299438 (Clockwise)

Preceding gene: 209396825

Following gene: 209400702

Centisome position: 23.31

GC content: 48.27

Gene sequence:

>549_bases
ATGTCTAAATACACGATTCCTTCGAAAATCTTCCTCGAAATGGGCGGCTGGCGTCAGCCGCTGCTGATGGTCGATAAAAT
TGCAGATTATAAATACGGTGAAAATGGCTTTGTCAGTGTCGTGAAACACGTCACCTATAACGAACCGTATCTACTGGGGC
ATTTCCCGGAAGATCCGATTATGCCCGGGGTGATTATTTCGGAAATCTTCGGCCAGGCCAGCGAGTATCTCTCTTTCCTG
ACCGACATTTGCGATATCTGGCGCGAACGTTTTGAGGAAGAGCTGAAGTCGTTACGTGATATTCACGCACGCATTCACCG
CCCTGAAATGCTGGAGATTATCCGTACCCGGCGCAGCCAGGTACGCGGCGTGCTGGCGGCTCAGAACCTGAAATTTAAAG
ATATCGCCTATCCGGGTGATTCTATTGATGTTGTCAGCAAATTGGCTTTTTCGGATGCCAGTGGCTTTAAACACTATTCC
GTGACCGCGTACGTCGGTAAAAAGCTGATTAGTCAGGGCACCATTATCAATTTCCGTGAAACCAAGTAA

Upstream 100 bases:

>100_bases
AGAAGTGGCGAACACCATCGTCTTCTTAAGTTCCTCTGCCTCCAGCTACATTGTCGGCCAGACCATCGTTATCGATGGCG
GCCTGGTCATGCGGTGATTT

Downstream 100 bases:

>100_bases
TCCAATAAGAGAGTAAATATTATGTCTACCATGAATGACGCTATTGAACAGCGTAAAGAAGTTCTGATGACCATTAAAAC
TGAGATCATCCAGCGACTGA

Product: hypothetical protein

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPIMPGVIISEIFGQASEYLSFL
TDICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTRRSQVRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYS
VTAYVGKKLISQGTIINFRETK

Sequences:

>Translated_182_residues
MSKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPIMPGVIISEIFGQASEYLSFL
TDICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTRRSQVRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYS
VTAYVGKKLISQGTIINFRETK
>Mature_181_residues
SKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPIMPGVIISEIFGQASEYLSFLT
DICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTRRSQVRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYSV
TAYVGKKLISQGTIINFRETK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=78, Percent_Identity=41.025641025641, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 20925; Mature: 20794

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPI
CCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCC
MPGVIISEIFGQASEYLSFLTDICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTRRSQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYSVTAYVGKKLISQGTIINFRE
HHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCEEEEEC
TK
CC
>Mature Secondary Structure 
SKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPI
CCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCC
MPGVIISEIFGQASEYLSFLTDICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTRRSQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYSVTAYVGKKLISQGTIINFRE
HHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCEEEEEC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA