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The map label for this gene is nagZ [H]

Identifier: 209396392

GI number: 209396392

Start: 1466793

End: 1467818

Strand: Direct

Name: nagZ [H]

Synonym: ECH74115_1487

Alternate gene names: 209396392

Gene position: 1466793-1467818 (Clockwise)

Preceding gene: 209395825

Following gene: 209396845

Centisome position: 26.32

GC content: 53.22

Gene sequence:

>1026_bases
GTGGGTCCAGTAATGTTGGATGTCGAAGGTTACGAACTGGACGCGGAAGAGCGTGAAATACTGGCGCATCCGCTGGTGGG
AGGGCTGATTCTCTTTACGCGAAACTATCATGATCCTGCCCAGTTGCGTGAACTGGTGCGCCAGATCCGCGCAGCATCGC
GCAATCATCTGGTGGTGGCGGTAGATCAGGAAGGTGGACGCGTCCAGCGTTTTCGCGAAGGTTTTACCCGCTTACCGGCA
GCACAATCCTTTGCTGCGCTGTTGGGAATGGAAGAGGGCGGCAAACTGGCGCAAGAGGCGGGTTGGCTGATGGCCAGCGA
AATGATCGCTATGGATATTGATATCAGCTTTGCGCCAGTGCTGGATGTAGGACATATCAGCGCGGCGATTGGCGAGCGTT
CTTATCATGCCGACCCAGAAAAAGCCCTGGCAATCGCCAGTCGGTTTATTGATGGGATGCATGAAGCCGGAATGAAAACG
ACCGGGAAACACTTCCCAGGACACGGTGCAGTAACTGCAGATTCACACAAAGAGACGCCGTGCGACCCACGCCCGCAAGC
GGAAATTCGTGCCAAAGATATGTCGGTTTTCAGCACGTTAATCCGCGAAAATAAACTCGACGCCATTATGCCTGCGCATG
TGATCTACAGTGATGTTGATCCGCGTCCGGCGAGCGGTTCTTCCTACTGGCTGAAAACCGTTTTGCGTCAGGAACTGGGT
TTTGACGGCGTGATTTTCTCTGACGATTTATCGATGGAAGGTGCCGCGATTATGGGCAGTTATGCCGAACGCGGGCAGGT
ATCACTGGATGCGGGTTGCGATATGATCCTGGTCTGCAATAATCGTAAAGGGGCCGTCAGCGTGTTAGATAATCTGTCAC
CGATCAAGGCAGAACGTGTTACACGTTTGTATCATAAAGGTTCATTTTCGCGACAGGAACTGATGGACTCGGCTCGCTGG
AAAGCGATCAGCGCCCGTCTGAATCAGTTACATGAACGCTGGCAGGAAGAGAAAGCAGGTCACTAA

Upstream 100 bases:

>100_bases
TGGTTTGAGTACCGCTGGCGACAAACCGGCGATCAACAATTTATCAGGCTGGCCGATGACACCTGGCGGCAGCTATTAAT
AAAACAATAAGGAGAGCAGT

Downstream 100 bases:

>100_bases
CCCTGGCTTATGTGAGGAAGCGATGATTATCTATTTACACGGTTTTGACTCTAACAGTCCGGGTAACCACGAGAAAGTCT
TACAATTGCAGTTTATTGAC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPA
AQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKT
TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELG
FDGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARW
KAISARLNQLHERWQEEKAGH

Sequences:

>Translated_341_residues
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPA
AQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKT
TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELG
FDGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARW
KAISARLNQLHERWQEEKAGH
>Mature_340_residues
GPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAA
QSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTT
GKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELGF
DGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWK
AISARLNQLHERWQEEKAGH

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=341, Percent_Identity=97.9472140762463, Blast_Score=689, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37605; Mature: 37474

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVA
CCCEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCH
LDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
CDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELG
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHEECCCCCCCCCCHHHHHHHHHHHCC
FDGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERV
CCCEEEECCCCCCCHHHHCCHHHCCCEEECCCCCEEEEECCCCCHHHHHHCCCCHHHHHH
TRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVA
CCEEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCH
LDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
CDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELG
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHEECCCCCCCCCCHHHHHHHHHHHCC
FDGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERV
CCCEEEECCCCCCCHHHHCCHHHCCCEEECCCCCEEEEECCCCCHHHHHHCCCCHHHHHH
TRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA