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The map label for this gene is yqaB [H]

Identifier: 209396302

GI number: 209396302

Start: 3645331

End: 3645897

Strand: Reverse

Name: yqaB [H]

Synonym: ECH74115_3936

Alternate gene names: 209396302

Gene position: 3645897-3645331 (Counterclockwise)

Preceding gene: 209399950

Following gene: 209396879

Centisome position: 65.43

GC content: 53.44

Gene sequence:

>567_bases
ATGTACGAGCGTTATGCAGGTTTAATTTTTGATATGGATGGCACAATCCTGGATACGGAGCCTACGCACCGTAAAGCGTG
GCGCGAAGTATTAGGGCACTACGGTCTTCAGTACGATGTTCAGGCGATGATTGCGCTTAATGGATCGCCCACCTGGCGTA
TTGCTCAGGCAATTATTGAGCTGAATCAGGCCGATCTCGACCCGCATGCGTTAGCGCGTGAAAAAACAGAAGCAGTAAGA
AGTATGCTGCTGGATAGTGTCGAGCCGCTTCCTCTTGTTGAAGTGGTGAAAAGTTGGCATGGTCGTCGCCCAATGGCTGT
AGGAACGGGGAGTGAAAGCGCCATCGCTGAGGCATTGCTGGCTCACCTGGGATTACGCCGTTATTTTGACGCCGTCGTCG
CTGCCGATCACGTCAAACACCATAAACCCGCGCCAGACACATTTTTGTTGTGCGCGCAGCGTATGGGCGTGCAACCGACG
CAGTGTGTGGTCTTTGAAGATGCCGATTTCGGTATTCAGGCGGCCCGTGCAGCAGGCATGGACGCTGTGGATGTTCGCTT
GCTGTGA

Upstream 100 bases:

>100_bases
ACTTTATCCATTTCCTGAATTTTCTTCTCCTTCGCCATCAGCGACAAAATCAAGCAATTACGCTAAAGTAGCGTCATATT
TTTCGACTTGCGAGAAGACC

Downstream 100 bases:

>100_bases
GTGAAGCGTTATCGCTTTTCTCGTTGTTTGCCAGTAGTTTTCTCAGCGCTACACTATTACCCGGCAACTCCGAAGTCGTG
CTGGTGGCAATGTTGCTTTC

Product: fructose-1-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVR
SMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
QCVVFEDADFGIQAARAAGMDAVDVRLL

Sequences:

>Translated_188_residues
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVR
SMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
QCVVFEDADFGIQAARAAGMDAVDVRLL
>Mature_188_residues
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVR
SMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
QCVVFEDADFGIQAARAAGMDAVDVRLL

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates fructose 1-phosphate and 6-phosphogluconate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=190, Percent_Identity=35.2631578947368, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI207113149, Length=213, Percent_Identity=31.4553990610329, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789046, Length=188, Percent_Identity=98.4042553191489, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1787576, Length=191, Percent_Identity=29.3193717277487, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788021, Length=184, Percent_Identity=30.9782608695652, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789787, Length=80, Percent_Identity=38.75, Blast_Score=64, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17137324, Length=185, Percent_Identity=32.4324324324324, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116008157, Length=188, Percent_Identity=30.3191489361702, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129151, Length=191, Percent_Identity=29.8429319371728, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010976
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 20799; Mature: 20799

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIE
CCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHH
LNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHH
AHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPTQCVVFEDADFGIQAARAAGM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCC
DAVDVRLL
CCEEEEEC
>Mature Secondary Structure
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIE
CCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHH
LNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHH
AHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPTQCVVFEDADFGIQAARAAGM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCC
DAVDVRLL
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]