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The map label for this gene is cobU [H]

Identifier: 20806893

GI number: 20806893

Start: 405312

End: 405860

Strand: Direct

Name: cobU [H]

Synonym: TTE0381

Alternate gene names: 20806893

Gene position: 405312-405860 (Clockwise)

Preceding gene: 20806892

Following gene: 20806894

Centisome position: 15.07

GC content: 35.7

Gene sequence:

>549_bases
ATGGGATTGATAATGGTAACAGGCGGTGCCAGGTCAGGAAAAAGTGAATTTGCAGAAAAATTGGCTTATGAAAGGGGGAA
AGATGAAGTTTTATATATAGCAACATCTCTTCCAGTAGATGAGGAAATGAAAGAAAGGATAAAAAGACACAGGGAAAGAA
GACCCTCTTCATGGGAGACAGTAGAAGCTTATAAAGACCTTGATAAGGAAATTTTAAAAAGAAAAAAGAAGGTTGTATTG
ATTGACTGCCTCACTGTTATGATAAGCAATCTCCTAATGGAAGTAGATTTGACATGGGAAAATTCTACTTTAGAGCAAAT
TGATGAAATAGAAGATAGGATAAGTCAAGAGGTAGATAAAATATTGATTGTATCAAGTGGCGTAGAAATAATAATTGTCA
CAAATGAGGTAGGAATGGGGCTGGTTCCTGAGTATAAACTTGGGAGGATTTTTAGAGATATAGCAGGCAGAATGAATAAA
AAAGTAGCAGAAGCATCAAAAGAGGTGTACCTTATGATATCAGGCATTCCTGTTAAGATAAAGGGGTAA

Upstream 100 bases:

>100_bases
TGGCTGTAAAAAGAAGGGAGGACAATATGTGCCTTATAGAGGCTTTAAGAGGATTGTACGAAGAAGGTGTCATGCCAGAT
AAAGAGAGGGTCGTAGTGTA

Downstream 100 bases:

>100_bases
TTGTATGGAAGAACTTAAGGCTTTAATACTTTCAATACAATTTATGACAGGTATTCCCATACCAATAAATATCGATGTTA
AAGAGGATAAGATTTATAAA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MGLIMVTGGARSGKSEFAEKLAYERGKDEVLYIATSLPVDEEMKERIKRHRERRPSSWETVEAYKDLDKEILKRKKKVVL
IDCLTVMISNLLMEVDLTWENSTLEQIDEIEDRISQEVDKILIVSSGVEIIIVTNEVGMGLVPEYKLGRIFRDIAGRMNK
KVAEASKEVYLMISGIPVKIKG

Sequences:

>Translated_182_residues
MGLIMVTGGARSGKSEFAEKLAYERGKDEVLYIATSLPVDEEMKERIKRHRERRPSSWETVEAYKDLDKEILKRKKKVVL
IDCLTVMISNLLMEVDLTWENSTLEQIDEIEDRISQEVDKILIVSSGVEIIIVTNEVGMGLVPEYKLGRIFRDIAGRMNK
KVAEASKEVYLMISGIPVKIKG
>Mature_181_residues
GLIMVTGGARSGKSEFAEKLAYERGKDEVLYIATSLPVDEEMKERIKRHRERRPSSWETVEAYKDLDKEILKRKKKVVLI
DCLTVMISNLLMEVDLTWENSTLEQIDEIEDRISQEVDKILIVSSGVEIIIVTNEVGMGLVPEYKLGRIFRDIAGRMNKK
VAEASKEVYLMISGIPVKIKG

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=188, Percent_Identity=44.6808510638298, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20717; Mature: 20585

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIMVTGGARSGKSEFAEKLAYERGKDEVLYIATSLPVDEEMKERIKRHRERRPSSWET
CCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHH
VEAYKDLDKEILKRKKKVVLIDCLTVMISNLLMEVDLTWENSTLEQIDEIEDRISQEVDK
HHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
ILIVSSGVEIIIVTNEVGMGLVPEYKLGRIFRDIAGRMNKKVAEASKEVYLMISGIPVKI
EEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEEE
KG
CC
>Mature Secondary Structure 
GLIMVTGGARSGKSEFAEKLAYERGKDEVLYIATSLPVDEEMKERIKRHRERRPSSWET
CEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHH
VEAYKDLDKEILKRKKKVVLIDCLTVMISNLLMEVDLTWENSTLEQIDEIEDRISQEVDK
HHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
ILIVSSGVEIIIVTNEVGMGLVPEYKLGRIFRDIAGRMNKKVAEASKEVYLMISGIPVKI
EEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEEE
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]