Click here to switch to the map view.

The map label for this gene is vsp [H]

Identifier: 203283925

GI number: 203283925

Start: 12569

End: 13282

Strand: Direct

Name: vsp [H]

Synonym: BDU_15013

Alternate gene names: 203283925

Gene position: 12569-13282 (Clockwise)

Preceding gene: 203283924

Following gene: NA

Centisome position: 83.52

GC content: 38.24

Gene sequence:

>714_bases
ATGAAAGAAGAGGGAATAAAAGGAATAAAAGGGAAGGAAGAATTGGGAAATATAGAGGAGTGTAGGATGGGAAGAAGAGT
AAAAGGAATAGTAATGGTGATGGTGGTGATGATGGGATGTAATAGTGGAGGAGTAAGTGGAGAAGGGACAGGAGAAGAAG
GGAAAGGAAGGAAGGGAGATGGGAGTGTAATAGATTTAAAGGGAGTAAGTAAAAAGATAAGAGATGCGGTGGAGTTTGCG
GGGAGTGTAAAGGAAGTGGAAACTTTAGTTAAGTCAATAGATGCACTTGCTAAAGCGATTGGAAAGAAAATTCAGGCTGC
TGGTGCTACTGCTGCCAATGCTAATCAGAATGATTCACTAGTTGTAGGAGCATACAATATAATATCAGATGCAAAGGCTA
AGTTAGAAGTATTAGAAGCTAAGGCTGGTAAGTTTAGTGGAATAAAGGAAAAGGTTGCATCTGCTAAGAGTTCAAGTAAA
TCTTTATTAGATAAATGGGCTGAAAGTCATGGTGATCTTGGTAAAGGTGGTGCTGAAGACAGTGCTGTAAAGAAAGCTAT
GGATAAAAGTGATGCTACTGGTGGTAAGGGGAAGAAAGAACTTGAGGATTTAAATAAAGAAATTGTTAGTTTGATTATCG
ATGTTACCAATGTAGTAGAAGATGAAATCAAGAAGCTTACAGAAAAACCTGTTAAACCCGCTTTTGGTGATTAA

Upstream 100 bases:

>100_bases
TTTATCATTTGAATTGTCATTCATTCGTTGCTGTATACATTTATTTTTTTATTTGTTTGCTTTCTTGTTAGAAAAAAACA
AATAAAAGGAGGCGAAGAAG

Downstream 100 bases:

>100_bases
AATCTTTAATAATAATATAGATCAATAAATAAGAGGCCAAGATATTAGTTATCTTGGCTTTGTTATGTTTATGTCTTTTA
TTTTTAGTGTTAAGTTAATG

Product: vsp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKEEGIKGIKGKEELGNIEECRMGRRVKGIVMVMVVMMGCNSGGVSGEGTGEEGKGRKGDGSVIDLKGVSKKIRDAVEFA
GSVKEVETLVKSIDALAKAIGKKIQAAGATAANANQNDSLVVGAYNIISDAKAKLEVLEAKAGKFSGIKEKVASAKSSSK
SLLDKWAESHGDLGKGGAEDSAVKKAMDKSDATGGKGKKELEDLNKEIVSLIIDVTNVVEDEIKKLTEKPVKPAFGD

Sequences:

>Translated_237_residues
MKEEGIKGIKGKEELGNIEECRMGRRVKGIVMVMVVMMGCNSGGVSGEGTGEEGKGRKGDGSVIDLKGVSKKIRDAVEFA
GSVKEVETLVKSIDALAKAIGKKIQAAGATAANANQNDSLVVGAYNIISDAKAKLEVLEAKAGKFSGIKEKVASAKSSSK
SLLDKWAESHGDLGKGGAEDSAVKKAMDKSDATGGKGKKELEDLNKEIVSLIIDVTNVVEDEIKKLTEKPVKPAFGD
>Mature_237_residues
MKEEGIKGIKGKEELGNIEECRMGRRVKGIVMVMVVMMGCNSGGVSGEGTGEEGKGRKGDGSVIDLKGVSKKIRDAVEFA
GSVKEVETLVKSIDALAKAIGKKIQAAGATAANANQNDSLVVGAYNIISDAKAKLEVLEAKAGKFSGIKEKVASAKSSSK
SLLDKWAESHGDLGKGGAEDSAVKKAMDKSDATGGKGKKELEDLNKEIVSLIIDVTNVVEDEIKKLTEKPVKPAFGD

Specific function: The vlp and vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune reponse evasion [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the variable small protein (vsp) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001800
- ProDom:   PD001149 [H]

Pfam domain/function: PF01441 Lipoprotein_6 [H]

EC number: NA

Molecular weight: Translated: 24750; Mature: 24750

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEGIKGIKGKEELGNIEECRMGRRVKGIVMVMVVMMGCNSGGVSGEGTGEEGKGRKGD
CCCCCCCCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GSVIDLKGVSKKIRDAVEFAGSVKEVETLVKSIDALAKAIGKKIQAAGATAANANQNDSL
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
VVGAYNIISDAKAKLEVLEAKAGKFSGIKEKVASAKSSSKSLLDKWAESHGDLGKGGAED
EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SAVKKAMDKSDATGGKGKKELEDLNKEIVSLIIDVTNVVEDEIKKLTEKPVKPAFGD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKEEGIKGIKGKEELGNIEECRMGRRVKGIVMVMVVMMGCNSGGVSGEGTGEEGKGRKGD
CCCCCCCCCCCHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GSVIDLKGVSKKIRDAVEFAGSVKEVETLVKSIDALAKAIGKKIQAAGATAANANQNDSL
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
VVGAYNIISDAKAKLEVLEAKAGKFSGIKEKVASAKSSSKSLLDKWAESHGDLGKGGAED
EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
SAVKKAMDKSDATGGKGKKELEDLNKEIVSLIIDVTNVVEDEIKKLTEKPVKPAFGD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8515101; 8087853 [H]