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The map label for this gene is queC

Identifier: 20094501

GI number: 20094501

Start: 1032777

End: 1033466

Strand: Direct

Name: queC

Synonym: MK1065

Alternate gene names: 20094501

Gene position: 1032777-1033466 (Clockwise)

Preceding gene: 20094500

Following gene: 20094502

Centisome position: 60.93

GC content: 64.49

Gene sequence:

>690_bases
GTGGCCACGACCGTCGTGTTGTGTAGCGGCGGGCTGGACTCCTCGGTTATCGCCAAGTGGGCGGTGGAGGAGCTCGGAGG
GCGCGTGATATGTCTTTTCGTCGATTATGGGCAGCGGAACGCACCCTTCGAGCGGAGGGCTGCGGAACGTATAGCCGAAG
CGGTGGGGGCCGAGTTCGAAACTGTCGGCACGTTCTGGCTGAGGCGCCTCTGCCCGGATAACCCCATGTTCGCCGGTAGA
CTGCCGCGTGAGGCCGGGACCGAGGATCTCTCGGCGAACTGGCTTCCGGCGAGGAACTGGAACCTCCTGGGGGTCGCGGC
GGCGCTCTGTGACCATCTGTACCTCGAGGGGGAAGACGACGAGTTCCACATCGTTTGGGGTATCAACGCCGAGGAAGCCG
AACGGTTTCCGGACAACACCAAGGAGTTCGCCGACGCCGTAGCTGAGGCGCTGAAGCGGGGACTGCCCTCGCGGCCGCGG
CTCCACAGTCCGTTGGCCGAGTTGTACAAGCCGGGCATAGTGCGCCTGGGCTCGGAGCTCGGTGCCCCGATGGAGCTCTC
CGTAAGTTGCTACAACCCGATCTGGGAGGACGACACGCCGGTGCACTGCGGAGAGTGTGAGGCGTGTTACCACCGTAAGC
GGGCCTTCGAGCGGGCGGGGATCGAAGATCCCACAGAGTATCTGGAGTGA

Upstream 100 bases:

>100_bases
CGACGTAACCCGTGACGACTTAAAAGCGTTGACGAAGATCGTACCCAGGTCGAAGCGCCCGTTCTACGGCTCCGAAGAGA
TGGAGGAGGGGTAAGAACCC

Downstream 100 bases:

>100_bases
CCTCGCCGCCCTCGGGACCACCGCCCTAATCGCGGCGAGTCCCATCGGCCACTGGCCCGCGATCGCCTACGGGCTCGCCC
ACGGCCTTCCCGCCCCCCTG

Product: PP-loop superfamily ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATTVVLCSGGLDSSVIAKWAVEELGGRVICLFVDYGQRNAPFERRAAERIAEAVGAEFETVGTFWLRRLCPDNPMFAGR
LPREAGTEDLSANWLPARNWNLLGVAAALCDHLYLEGEDDEFHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPR
LHSPLAELYKPGIVRLGSELGAPMELSVSCYNPIWEDDTPVHCGECEACYHRKRAFERAGIEDPTEYLE

Sequences:

>Translated_229_residues
MATTVVLCSGGLDSSVIAKWAVEELGGRVICLFVDYGQRNAPFERRAAERIAEAVGAEFETVGTFWLRRLCPDNPMFAGR
LPREAGTEDLSANWLPARNWNLLGVAAALCDHLYLEGEDDEFHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPR
LHSPLAELYKPGIVRLGSELGAPMELSVSCYNPIWEDDTPVHCGECEACYHRKRAFERAGIEDPTEYLE
>Mature_228_residues
ATTVVLCSGGLDSSVIAKWAVEELGGRVICLFVDYGQRNAPFERRAAERIAEAVGAEFETVGTFWLRRLCPDNPMFAGRL
PREAGTEDLSANWLPARNWNLLGVAAALCDHLYLEGEDDEFHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPRL
HSPLAELYKPGIVRLGSELGAPMELSVSCYNPIWEDDTPVHCGECEACYHRKRAFERAGIEDPTEYLE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_METKA (Q8TWG9)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614348.1
- ProteinModelPortal:   Q8TWG9
- SMR:   Q8TWG9
- GeneID:   1477166
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1065
- NMPDR:   fig|190192.1.peg.1061
- HOGENOM:   HBG553284
- OMA:   TERACAQ
- BioCyc:   MKAN190192:MK1065-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- PIRSF:   PIRSF006293

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25498; Mature: 25367

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTVVLCSGGLDSSVIAKWAVEELGGRVICLFVDYGQRNAPFERRAAERIAEAVGAEFE
CCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHH
TVGTFWLRRLCPDNPMFAGRLPREAGTEDLSANWLPARNWNLLGVAAALCDHLYLEGEDD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCC
EFHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPRLHSPLAELYKPGIVRLGSEL
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHH
GAPMELSVSCYNPIWEDDTPVHCGECEACYHRKRAFERAGIEDPTEYLE
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure 
ATTVVLCSGGLDSSVIAKWAVEELGGRVICLFVDYGQRNAPFERRAAERIAEAVGAEFE
CEEEEEECCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHH
TVGTFWLRRLCPDNPMFAGRLPREAGTEDLSANWLPARNWNLLGVAAALCDHLYLEGEDD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCC
EFHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPRLHSPLAELYKPGIVRLGSEL
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHH
GAPMELSVSCYNPIWEDDTPVHCGECEACYHRKRAFERAGIEDPTEYLE
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014