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The map label for this gene is CobL_1 [H]

Identifier: 20094473

GI number: 20094473

Start: 999306

End: 999872

Strand: Reverse

Name: CobL_1 [H]

Synonym: MK1037

Alternate gene names: 20094473

Gene position: 999872-999306 (Counterclockwise)

Preceding gene: 20094477

Following gene: 20094472

Centisome position: 58.99

GC content: 66.14

Gene sequence:

>567_bases
GTGTTCAATGTCGTAGACCCCTCCGACTTGGTCACAGAGGGTGTTCCAGGCCCCACCAAGCCGGTGATGAAAGCGACGGT
GCTGGCCGTACTTCGACCGCGACCGGGCGAGAGGATCCTCGAGATCGGTGCGGGATCGGGCTCGCTAACCCTAGAGCTGG
CCCGGGCGGTAGGGCCTCTCGGCCGCGTGTACGCGGTGGAAGGAGACAAGGAAGCGTTCCGATCGTTGGAGCGGAACGTC
CGGGACTTCTGCCTGGAGGATCGCATAGAGATAGTGCGCGGGTGGGCCCCCGAGGCCCTGGAGGACGTGGACGAGGTGGA
CGCCGCCGTCGTGTCCGGTTCCGAGCGGCTGGAAGAGGTACTCCTCGCCCTCGCCGAGCGCGTGCGACGCGCGATACTGC
TAAACGCCGTCACACCCGAGACCTTCGCCACGGCGGTCAAGGCGCTCGACGGCTGGAGACGATCCTGCCTATGCATGGTG
TGGGGAGAAGGGAAGGTCCTCCGGCGGGGGACGCTGTTCTCGGGGATGAGAACGTCCTACCTGGCGCTCTTCGAGCCCGA
GAGGTGA

Upstream 100 bases:

>100_bases
CATCGCGACGGGTACCTTCTTTATAATCCTGATCGCCTTACGAGTTAGCAGGTCGGGATCCCCGGGGCCCAGGCCCACTC
CGTACAGGGTGGGTGCTCCC

Downstream 100 bases:

>100_bases
ACCCGAATGTTGCCCGCCCTCGTGCTGATAATCGCGGTATCCATCGCGATGACGCCCGCTCACGGTCGAGTGGGAGGGTT
CGTCTCCGGTCATTACTACT

Product: precorrin-6B methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MFNVVDPSDLVTEGVPGPTKPVMKATVLAVLRPRPGERILEIGAGSGSLTLELARAVGPLGRVYAVEGDKEAFRSLERNV
RDFCLEDRIEIVRGWAPEALEDVDEVDAAVVSGSERLEEVLLALAERVRRAILLNAVTPETFATAVKALDGWRRSCLCMV
WGEGKVLRRGTLFSGMRTSYLALFEPER

Sequences:

>Translated_188_residues
MFNVVDPSDLVTEGVPGPTKPVMKATVLAVLRPRPGERILEIGAGSGSLTLELARAVGPLGRVYAVEGDKEAFRSLERNV
RDFCLEDRIEIVRGWAPEALEDVDEVDAAVVSGSERLEEVLLALAERVRRAILLNAVTPETFATAVKALDGWRRSCLCMV
WGEGKVLRRGTLFSGMRTSYLALFEPER
>Mature_188_residues
MFNVVDPSDLVTEGVPGPTKPVMKATVLAVLRPRPGERILEIGAGSGSLTLELARAVGPLGRVYAVEGDKEAFRSLERNV
RDFCLEDRIEIVRGWAPEALEDVDEVDAAVVSGSERLEEVLLALAERVRRAILLNAVTPETFATAVKALDGWRRSCLCMV
WGEGKVLRRGTLFSGMRTSYLALFEPER

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014008
- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: 1.-.-.-

Molecular weight: Translated: 20623; Mature: 20623

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNVVDPSDLVTEGVPGPTKPVMKATVLAVLRPRPGERILEIGAGSGSLTLELARAVGPL
CCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCC
GRVYAVEGDKEAFRSLERNVRDFCLEDRIEIVRGWAPEALEDVDEVDAAVVSGSERLEEV
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
LLALAERVRRAILLNAVTPETFATAVKALDGWRRSCLCMVWGEGKVLRRGTLFSGMRTSY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEECCHHHHCHHHHE
LALFEPER
EEEECCCC
>Mature Secondary Structure
MFNVVDPSDLVTEGVPGPTKPVMKATVLAVLRPRPGERILEIGAGSGSLTLELARAVGPL
CCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCC
GRVYAVEGDKEAFRSLERNVRDFCLEDRIEIVRGWAPEALEDVDEVDAAVVSGSERLEEV
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
LLALAERVRRAILLNAVTPETFATAVKALDGWRRSCLCMVWGEGKVLRRGTLFSGMRTSY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEECCHHHHCHHHHE
LALFEPER
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]