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The map label for this gene is LepB

Identifier: 20094467

GI number: 20094467

Start: 991571

End: 992038

Strand: Reverse

Name: LepB

Synonym: MK1031

Alternate gene names: NA

Gene position: 992038-991571 (Counterclockwise)

Preceding gene: 20094469

Following gene: 20094460

Centisome position: 58.53

GC content: 60.68

Gene sequence:

>468_bases
ATGGGGTGGTCCGCGTTGAACGTCAAGAGGGCTTGGAGGAAAGTAAGAGAACTCAGGGGCTGGAAAGCCGCGGTCTTCTA
CGTGGTCCTAGGAGTGGCCCTGGGGTACGGCCTCAGGTACGGGCTCGGATTCGTGCTGGGCACGCCCGATCCGGTGGTCA
CGGTGATCTCCGAGAGTATGTACCCGTACTACAACGTCGGCGACGTGCTCCTGGTCGTCGGGGTCCCGTACCGTGACATC
AAAGTCGGAGACGTCATCGTGTACCGGCTGCCTGGGAAACCGATCCCAGTGGTTCACAGGGTGATAGCCAAAACGCCGGA
GGGCGTCATCACCAAGGGAGACAACAACCCGTTGCCCGATCCATGGTGCCCGATCCGGCCCAAGGAGATCAGCGGTAGGG
TGGTTCTCAGGATACCATACGTAGGGTACCCGAAAGCGCTCCTCGACAGGTACTTGTACGGGGGCTAG

Upstream 100 bases:

>100_bases
GTTATGAAATAGGTTTGAGATGGCAAAGTTTCAGCGATGGAGCAGTACGTAGGGGTTTCACACGGTCCGGTGGCTATTTC
TCGACCCGTTCCGGTGGTCT

Downstream 100 bases:

>100_bases
TCCCCCACCCAGCCACGGTCCTGTCCCGGATAATGCGGGATTCTGGCGAGAAGGAGGAAGGGTTCACTCCTCCACTCGCG
GCGCGAGGTAGAACGTCAAC

Product: Type I signal peptidase

Products: NA

Alternate protein names: Type I Signal Peptidase; Signal Peptidase; Peptidase

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MGWSALNVKRAWRKVRELRGWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVTVISESMYPYYNVGDVLLVVGVPYRDI
KVGDVIVYRLPGKPIPVVHRVIAKTPEGVITKGDNNPLPDPWCPIRPKEISGRVVLRIPYVGYPKALLDRYLYGG

Sequences:

>Translated_155_residues
MGWSALNVKRAWRKVRELRGWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVTVISESMYPYYNVGDVLLVVGVPYRDI
KVGDVIVYRLPGKPIPVVHRVIAKTPEGVITKGDNNPLPDPWCPIRPKEISGRVVLRIPYVGYPKALLDRYLYGG
>Mature_154_residues
GWSALNVKRAWRKVRELRGWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVTVISESMYPYYNVGDVLLVVGVPYRDIK
VGDVIVYRLPGKPIPVVHRVIAKTPEGVITKGDNNPLPDPWCPIRPKEISGRVVLRIPYVGYPKALLDRYLYGG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657609, Length=150, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI15150809, Length=147, Percent_Identity=30.6122448979592, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17510347, Length=143, Percent_Identity=32.1678321678322, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358147, Length=122, Percent_Identity=35.2459016393443, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.21.89

Molecular weight: Translated: 17253; Mature: 17121

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWSALNVKRAWRKVRELRGWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVTVISESM
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCC
YPYYNVGDVLLVVGVPYRDIKVGDVIVYRLPGKPIPVVHRVIAKTPEGVITKGDNNPLPD
CCCCCCCCEEEEECCCCCCEEECCEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCCCCC
PWCPIRPKEISGRVVLRIPYVGYPKALLDRYLYGG
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
GWSALNVKRAWRKVRELRGWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVTVISESM
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCC
YPYYNVGDVLLVVGVPYRDIKVGDVIVYRLPGKPIPVVHRVIAKTPEGVITKGDNNPLPD
CCCCCCCCEEEEECCCCCCEEECCEEEEECCCCCHHHHHHHHHCCCCCEEECCCCCCCCC
PWCPIRPKEISGRVVLRIPYVGYPKALLDRYLYGG
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA