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The map label for this gene is hisC2 [H]

Identifier: 20094460

GI number: 20094460

Start: 985790

End: 986929

Strand: Reverse

Name: hisC2 [H]

Synonym: MK1024

Alternate gene names: 20094460

Gene position: 986929-985790 (Counterclockwise)

Preceding gene: 20094467

Following gene: 20094459

Centisome position: 58.23

GC content: 59.65

Gene sequence:

>1140_bases
GTGGGGCCGGTGTCAGCCGACTGGATTCCCGATTCACCGGACGAACTATTCCGGAAGATACATTCCGGCGAGGTGATAGA
GCTCGGCCAGAACACCAATCGACTGGGACCCCCCGAGGAGGTCCGTAGAGCGGTCGTGCGCGCCGCACTGGAGGCACCGT
ACAACGTGTACGCACACCCGCAGGGCGACCGGCGACTTCGAGAGGGACTCCTGGAGTACTTCGAACTCGACGACGATTTC
GACGCCGTGATCACCAACGGCGCCATCGAGGGCGTCCACGCCGTCATCAGGGCGTTCGCCAGCAACGGTGTGGCCGTGAC
TCCGGATCCAGGGTACAAGACGATCGACGGTATGATGATGGCGGAGGGAGTTCACGTCCAAGAGGTCGACATATACTCCG
AGGAGTTCGACTATCAGATGACGGTAGACGCCGTGATGGAGGAGTTCGATGGTAACCTCCGGGAGCTCGATCTCATTTTC
GTAATAAACCCTTCCAACCCGCTCGGCAGCTCCATGTCCGAGCGGGAGCTCCGGGGTCTCGTGGAGCTCGCCCAAGATGC
GGACGCATTCCTGGTACACGACTGCACGTACAGGGACTTCGCTCCGGAGCAACCAGTAGCCTGCGAGATGGACCCGGAAC
GCTGCGTCGACCTGTACAGTTTCTCCAAGACGTACGGACTCGCCGGCCTTCGGATCGGAGCCGTGATCGGAGAGCGGAAA
CTGCTGGAGCAGGTATCCAAGTACAAGGTGAGCAAGTTAGGGATAAACCTGATAGCTCAGGAGGCCGCCATCACCGCCTT
GAAGGTTCGCGATCGATGGATCCCGAGACTGCTCAGGGAGGTCACGCGGAACCAGCGTCTGATCAAGCGCGAGTGTGAGG
GAGACGGAGTGAAGATACCGGTGTACCCCTCGCACGCCAACTGTCTCGTGATCGACTTCTCCGAGTACGGGTATATCGAC
TCGAAAACCGTCGTGGGTAAACTGTACTCCGAGCACGGTATCTTCGTGAGGACGGGCTACTATACCAGCCCACGCCGCGG
TAAGGGGTTCATCCGAGTGGCGTTTTCGGCCCCACGGGAGGACATAGAGCGGTTCTGTGAGGCCTTCAACGAGGTTATGG
GGGAGTTGATCAAGTCGTGA

Upstream 100 bases:

>100_bases
AGTTCCAAGATGTCACGGGCGCGGCCGCTGAGGCGCGATCTCGATACCCCCAATACCTTTCGGTATTTACACAAAAGTCT
GGCGGTCTAAAGTCCTCGGG

Downstream 100 bases:

>100_bases
GCTCTGAGATCGTTCTGGAGCACGATGTGCTTACCGCGCTTCGTGAGGGCGGTCTCAAAACGCCACGCTTCACCGTCCTC
GAGCGCCCCGAGGAGGCCTC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MGPVSADWIPDSPDELFRKIHSGEVIELGQNTNRLGPPEEVRRAVVRAALEAPYNVYAHPQGDRRLREGLLEYFELDDDF
DAVITNGAIEGVHAVIRAFASNGVAVTPDPGYKTIDGMMMAEGVHVQEVDIYSEEFDYQMTVDAVMEEFDGNLRELDLIF
VINPSNPLGSSMSERELRGLVELAQDADAFLVHDCTYRDFAPEQPVACEMDPERCVDLYSFSKTYGLAGLRIGAVIGERK
LLEQVSKYKVSKLGINLIAQEAAITALKVRDRWIPRLLREVTRNQRLIKRECEGDGVKIPVYPSHANCLVIDFSEYGYID
SKTVVGKLYSEHGIFVRTGYYTSPRRGKGFIRVAFSAPREDIERFCEAFNEVMGELIKS

Sequences:

>Translated_379_residues
MGPVSADWIPDSPDELFRKIHSGEVIELGQNTNRLGPPEEVRRAVVRAALEAPYNVYAHPQGDRRLREGLLEYFELDDDF
DAVITNGAIEGVHAVIRAFASNGVAVTPDPGYKTIDGMMMAEGVHVQEVDIYSEEFDYQMTVDAVMEEFDGNLRELDLIF
VINPSNPLGSSMSERELRGLVELAQDADAFLVHDCTYRDFAPEQPVACEMDPERCVDLYSFSKTYGLAGLRIGAVIGERK
LLEQVSKYKVSKLGINLIAQEAAITALKVRDRWIPRLLREVTRNQRLIKRECEGDGVKIPVYPSHANCLVIDFSEYGYID
SKTVVGKLYSEHGIFVRTGYYTSPRRGKGFIRVAFSAPREDIERFCEAFNEVMGELIKS
>Mature_378_residues
GPVSADWIPDSPDELFRKIHSGEVIELGQNTNRLGPPEEVRRAVVRAALEAPYNVYAHPQGDRRLREGLLEYFELDDDFD
AVITNGAIEGVHAVIRAFASNGVAVTPDPGYKTIDGMMMAEGVHVQEVDIYSEEFDYQMTVDAVMEEFDGNLRELDLIFV
INPSNPLGSSMSERELRGLVELAQDADAFLVHDCTYRDFAPEQPVACEMDPERCVDLYSFSKTYGLAGLRIGAVIGERKL
LEQVSKYKVSKLGINLIAQEAAITALKVRDRWIPRLLREVTRNQRLIKRECEGDGVKIPVYPSHANCLVIDFSEYGYIDS
KTVVGKLYSEHGIFVRTGYYTSPRRGKGFIRVAFSAPREDIERFCEAFNEVMGELIKS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=226, Percent_Identity=27.4336283185841, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786816, Length=306, Percent_Identity=23.8562091503268, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 42600; Mature: 42469

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVSADWIPDSPDELFRKIHSGEVIELGQNTNRLGPPEEVRRAVVRAALEAPYNVYAHP
CCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEECC
QGDRRLREGLLEYFELDDDFDAVITNGAIEGVHAVIRAFASNGVAVTPDPGYKTIDGMMM
CCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHCCHHH
AEGVHVQEVDIYSEEFDYQMTVDAVMEEFDGNLRELDLIFVINPSNPLGSSMSERELRGL
HCCCEEEEEECHHHHCCCEEEHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
VELAQDADAFLVHDCTYRDFAPEQPVACEMDPERCVDLYSFSKTYGLAGLRIGAVIGERK
HHHHHCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLEQVSKYKVSKLGINLIAQEAAITALKVRDRWIPRLLREVTRNQRLIKRECEGDGVKIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VYPSHANCLVIDFSEYGYIDSKTVVGKLYSEHGIFVRTGYYTSPRRGKGFIRVAFSAPRE
EECCCCCEEEEECHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCHH
DIERFCEAFNEVMGELIKS
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GPVSADWIPDSPDELFRKIHSGEVIELGQNTNRLGPPEEVRRAVVRAALEAPYNVYAHP
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEECC
QGDRRLREGLLEYFELDDDFDAVITNGAIEGVHAVIRAFASNGVAVTPDPGYKTIDGMMM
CCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHCCHHH
AEGVHVQEVDIYSEEFDYQMTVDAVMEEFDGNLRELDLIFVINPSNPLGSSMSERELRGL
HCCCEEEEEECHHHHCCCEEEHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
VELAQDADAFLVHDCTYRDFAPEQPVACEMDPERCVDLYSFSKTYGLAGLRIGAVIGERK
HHHHHCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLEQVSKYKVSKLGINLIAQEAAITALKVRDRWIPRLLREVTRNQRLIKRECEGDGVKIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VYPSHANCLVIDFSEYGYIDSKTVVGKLYSEHGIFVRTGYYTSPRRGKGFIRVAFSAPRE
EECCCCCEEEEECHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCHH
DIERFCEAFNEVMGELIKS
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]