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The map label for this gene is MurE_1

Identifier: 20094362

GI number: 20094362

Start: 884275

End: 885705

Strand: Direct

Name: MurE_1

Synonym: MK0926

Alternate gene names: NA

Gene position: 884275-885705 (Clockwise)

Preceding gene: 20094360

Following gene: 20094363

Centisome position: 52.17

GC content: 61.77

Gene sequence:

>1431_bases
GTGTCCTTGAGGTCGAAACTGGCCGACTTGGCCGGACTCCTCGCGCTCAAGGCGGTTCGGTTCGGGCCCGGTATGGGGCG
GAGCTTTCCCGGATGGACCGTGATCAAGGTCGGCGGCTTCGACGCCGTTCGCGAGCTCGCACGGCGGCCGGAGTACGGAG
TGGTGCTGATTACAGGTACCAACGGTAAGACCACGACCACCAGACTCGCCTGTGCGCTCCTAGCCGAAGATGCGGAGGTT
TCGTGCAACTACGATAGTAACACAATCAACGCCGTCACGACGGGCCTACTCAAGGGTAGGAAGGCCGAGCTCGTGGTGAC
GGAGTACGGGATTCGCAGCCGTGAGTACGGGATTCCAGATACCGTCTGCGAGCTCGTGGACCCGCTGGCGATCGCGTACA
CAACTATCTCGAAGGAACACTTCCGGGAGAACGCGGACAAGAAGGACCCGTTCGGGGCGTACTTCGAGGCGAAGCGTCTC
CTGGCGAGGCCCCTGAAGGACGGTGTGCTGGTGCTCAACGCGGATGATCCTCGGGTCACCTACATCCGCGACGAGAAGCG
CGGTGACCCCGTGGAGTACGTTTTCTACGGTTTGGAGGTTGAAATCGAGGATCTGACGCCACCGACCGAAGAGCTCGAGT
GTCCCGCGTGCGGCGGCGAGTTGGACTACGAGACCCGCTACTTTAACCATAAGGGACTGTACTCGTGTCGAGACTGCGAG
TTCTCACGGCCTGACCCGGACGTCGCCGTGGTAAGGCTAAAGGGCGGCCCGGACGAGTGGGAGGTCACGCTGTCGTACGA
TGTGACCAACGCCGTGATCGGAGAACGACTGGAGGGAAAGGTCACCTATGAGCTACCGCTGCCCGGTCTCCATAACGTCT
ACAACAGCGTTTGCGCGATCTCCCTGTACCTCGCGGTTACCCCCCGGCCCGAGGACCCGGAGGGAACGATCCGACGGGTG
ATCGAAGGGTTGAACCCGCTCGAGTTCATTCCGTCGGGCAGGTTCGAGGTGCTGAACGTGGGTGGTAAGCCCGTCGGCGT
CGGTCAGGGAGACAACGGGGACGCCTTCAAGGCCAACGCGAACCTGATGCTTTCGGTGGCGGGGGATGTAGGGGCCTGTG
TGTATACCACCCCGGACGAGGGTGAACATCCGATCTTCGAGATGCACAGGATTATCCTCCGAGCTCTCGAACCAGACGAG
CTATACGTGTTTCCTGGTAGGGAGTCCGTGAAGGCCGCGGAAGAGTACTACGAGGAACTGACCGAGGAGTTCGACGCAGA
GTTCTACCCTATCCCGCACGAGCGGATGCAGGAGAAAGTCGAGGAGATGCGTAGGGTGTGTGAGGAGGCGGATGGTCCCG
TGTTCGCCTCCGGGTGCGGGCCGGAGCGCGAGATGTGGGAAGCCCTGAAGAGGGAGCTCAGGGGCGGCTGA

Upstream 100 bases:

>100_bases
GTCAGTGCGGGGGTCCACCTCACGTTAACACCCCCTCACTCCGCAGCCGGGATCGTTAATCAAACTACGGGAAACACGTT
ACACCGGTAGGGGACGTGTC

Downstream 100 bases:

>100_bases
ATGGGGCTGAGGCGCCTCCTGGGGCTAGTCGGGGTCGGGTTGATCGTTCTGTACTTCACTCTACTTTCCGCAGAGTATTC
GGAGTTTCAACGCTTCCTCG

Product: UDP-N-acetylmuramyl tripeptide synthase

Products: NA

Alternate protein names: Peptide Ligase; UDP-N-Acetylmuramyl Tripeptide Synthetase; Conserved Domain Protein; Mur Ligase Family Protein

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSLRSKLADLAGLLALKAVRFGPGMGRSFPGWTVIKVGGFDAVRELARRPEYGVVLITGTNGKTTTTRLACALLAEDAEV
SCNYDSNTINAVTTGLLKGRKAELVVTEYGIRSREYGIPDTVCELVDPLAIAYTTISKEHFRENADKKDPFGAYFEAKRL
LARPLKDGVLVLNADDPRVTYIRDEKRGDPVEYVFYGLEVEIEDLTPPTEELECPACGGELDYETRYFNHKGLYSCRDCE
FSRPDPDVAVVRLKGGPDEWEVTLSYDVTNAVIGERLEGKVTYELPLPGLHNVYNSVCAISLYLAVTPRPEDPEGTIRRV
IEGLNPLEFIPSGRFEVLNVGGKPVGVGQGDNGDAFKANANLMLSVAGDVGACVYTTPDEGEHPIFEMHRIILRALEPDE
LYVFPGRESVKAAEEYYEELTEEFDAEFYPIPHERMQEKVEEMRRVCEEADGPVFASGCGPEREMWEALKRELRGG

Sequences:

>Translated_476_residues
MSLRSKLADLAGLLALKAVRFGPGMGRSFPGWTVIKVGGFDAVRELARRPEYGVVLITGTNGKTTTTRLACALLAEDAEV
SCNYDSNTINAVTTGLLKGRKAELVVTEYGIRSREYGIPDTVCELVDPLAIAYTTISKEHFRENADKKDPFGAYFEAKRL
LARPLKDGVLVLNADDPRVTYIRDEKRGDPVEYVFYGLEVEIEDLTPPTEELECPACGGELDYETRYFNHKGLYSCRDCE
FSRPDPDVAVVRLKGGPDEWEVTLSYDVTNAVIGERLEGKVTYELPLPGLHNVYNSVCAISLYLAVTPRPEDPEGTIRRV
IEGLNPLEFIPSGRFEVLNVGGKPVGVGQGDNGDAFKANANLMLSVAGDVGACVYTTPDEGEHPIFEMHRIILRALEPDE
LYVFPGRESVKAAEEYYEELTEEFDAEFYPIPHERMQEKVEEMRRVCEEADGPVFASGCGPEREMWEALKRELRGG
>Mature_475_residues
SLRSKLADLAGLLALKAVRFGPGMGRSFPGWTVIKVGGFDAVRELARRPEYGVVLITGTNGKTTTTRLACALLAEDAEVS
CNYDSNTINAVTTGLLKGRKAELVVTEYGIRSREYGIPDTVCELVDPLAIAYTTISKEHFRENADKKDPFGAYFEAKRLL
ARPLKDGVLVLNADDPRVTYIRDEKRGDPVEYVFYGLEVEIEDLTPPTEELECPACGGELDYETRYFNHKGLYSCRDCEF
SRPDPDVAVVRLKGGPDEWEVTLSYDVTNAVIGERLEGKVTYELPLPGLHNVYNSVCAISLYLAVTPRPEDPEGTIRRVI
EGLNPLEFIPSGRFEVLNVGGKPVGVGQGDNGDAFKANANLMLSVAGDVGACVYTTPDEGEHPIFEMHRIILRALEPDEL
YVFPGRESVKAAEEYYEELTEEFDAEFYPIPHERMQEKVEEMRRVCEEADGPVFASGCGPEREMWEALKRELRGG

Specific function: Unknown

COG id: COG0769

COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52842; Mature: 52711

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRSKLADLAGLLALKAVRFGPGMGRSFPGWTVIKVGGFDAVRELARRPEYGVVLITGT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECC
NGKTTTTRLACALLAEDAEVSCNYDSNTINAVTTGLLKGRKAELVVTEYGIRSREYGIPD
CCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
TVCELVDPLAIAYTTISKEHFRENADKKDPFGAYFEAKRLLARPLKDGVLVLNADDPRVT
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEE
YIRDEKRGDPVEYVFYGLEVEIEDLTPPTEELECPACGGELDYETRYFNHKGLYSCRDCE
EEECCCCCCCEEEEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCEECCCC
FSRPDPDVAVVRLKGGPDEWEVTLSYDVTNAVIGERLEGKVTYELPLPGLHNVYNSVCAI
CCCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHEE
SLYLAVTPRPEDPEGTIRRVIEGLNPLEFIPSGRFEVLNVGGKPVGVGQGDNGDAFKANA
EEEEEECCCCCCCCHHHHHHHHCCCCHHCCCCCCEEEEECCCCEEECCCCCCCCEEEECC
NLMLSVAGDVGACVYTTPDEGEHPIFEMHRIILRALEPDELYVFPGRESVKAAEEYYEEL
CEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
TEEFDAEFYPIPHERMQEKVEEMRRVCEEADGPVFASGCGPEREMWEALKRELRGG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLRSKLADLAGLLALKAVRFGPGMGRSFPGWTVIKVGGFDAVRELARRPEYGVVLITGT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECC
NGKTTTTRLACALLAEDAEVSCNYDSNTINAVTTGLLKGRKAELVVTEYGIRSREYGIPD
CCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCH
TVCELVDPLAIAYTTISKEHFRENADKKDPFGAYFEAKRLLARPLKDGVLVLNADDPRVT
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEE
YIRDEKRGDPVEYVFYGLEVEIEDLTPPTEELECPACGGELDYETRYFNHKGLYSCRDCE
EEECCCCCCCEEEEEEEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCEECCCC
FSRPDPDVAVVRLKGGPDEWEVTLSYDVTNAVIGERLEGKVTYELPLPGLHNVYNSVCAI
CCCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHEE
SLYLAVTPRPEDPEGTIRRVIEGLNPLEFIPSGRFEVLNVGGKPVGVGQGDNGDAFKANA
EEEEEECCCCCCCCHHHHHHHHCCCCHHCCCCCCEEEEECCCCEEECCCCCCCCEEEECC
NLMLSVAGDVGACVYTTPDEGEHPIFEMHRIILRALEPDELYVFPGRESVKAAEEYYEEL
CEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
TEEFDAEFYPIPHERMQEKVEEMRRVCEEADGPVFASGCGPEREMWEALKRELRGG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA