BacMap

Definition	Methanopyrus kandleri AV19, complete genome.
Accession	NC_003551
Length	1,694,969

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The map label for this gene is RPT1

Identifier: 20094314

GI number: 20094314

Start: 828838

End: 830148

Strand: Direct

Name: RPT1

Synonym: MK0878

Alternate gene names: 20094314

Gene position: 828838-830148 (Clockwise)

Preceding gene: 20094313

Following gene: 20094315

Centisome position: 48.9

GC content: 60.26

Gene sequence:

>1311_bases
ATGGAAGAAACAGGCGTGAAAGACGTGAGGGATCTCTGCGAGAAGTTTCTGGACTTCAAGCGTGAAAAGGAGCGGTTGGA
AGAGCTCCTCAAGGAGTACTTCAAGCGGTTGGAGGAGTTGGAGCGGAAGCTGCGAGCCCACGAGGAGAAGCTTCGCATCG
AGGCCCGTCGTCGTAAGACTCTGGAGAAGGAGTTGGAGATGGAGCGCGACGAGAAGGCCGAGCTGCGGGAGGAGCTACGG
CGTAAAGAAGTCATGATCGAGAAGCTCCGTAGCGACCTGCAGCGGATGAAGAAGCCCCCGCTCATCGTGGGTACCGTCGA
AGAGATCCTCGACGACGGTCGCGTGATAGTGAAGAGTTCCACGGGTCCGAAGTTCGTCTCGAACGTGAGCCCGACCGTAG
ACAGAAACGAGCTCGAGCCGGGTGCTAACGTGGCCCTCAACCAGCAGAGCATGGCCGTGGTGGACGTGTTACCGTCGGAG
AAAGACTCACGTGTACTGGCGATGGAGGTGGACGAGTCACCCGATGTGTCGTACGACGATATCGGCGGTCTGGACGAGCA
GATCCGCGAGATCCGAGAAGTCGTGGAGAAGCCGCTCAAGGAGCCCGAGCTGTTCGAGAAGGTCGGTGTCGAACCGCCGA
AGGGTGTCCTACTGTACGGTCCACCGGGCACCGGTAAGACCCTGCTGGCCAAAGCCGTGGCGAACCACGCCGACGCCACC
TTCATCCGGCTCGCCGCGCCGGAATTGGTCCAGAAGTTCATCGGCGAAGGTGCTAGACTGGTGCGGGAGCTGTTCGAACT
CGCACGCGAGAAGGCTCCGAGTATTATCTTCATCGACGAGATCGACGCGATCGGTGCCCGGCGAATGCGGGACGCGACGA
GCGGAGACCGCGAGGTCCAGCGCACGCTCACCCAGCTGCTCGCGGAGATGGACGGCTTCGATCCGCTCGACGACATCAAG
GTCATCGCGGCCACGAACCGGAAGGACATCCTGGACCCGGCCTTGCTGCGACCGGGTCGGTTCGACAGGCACATTAAGAT
CCCGCTACCGGACGAGGAGGGCCGGTACGAGATCTTCAAGATCCACACGCGCGACATGAACTTGGCCGAGGACGTCGATC
TCCAGAAGCTGGCGAAGATCACCGAGGGTGCCTCAGGTGCGGACATCAAGGCCATATGTACCGAGGCTGGTATGATGGCT
ATACGCGAGGACCGTGACATTGTCACCATGGATGACTTCCTGAAGGCCGTGGACAGGGTCATGGGTAAGAAGGAAGAAGA
GAGCGGAGAGTTCAAGCGCGCGTACCACTGA

Upstream 100 bases:

>100_bases
TCTGAAGAACCTCCGCGATGCGCTGGATAAGTTTTCCGAGATCGAGCCGGATCTGGACGTCGAGTCGCTGAAAGCTACGC
TGGACGATCTGATCACGCTC

Downstream 100 bases:

>100_bases
TGCGGACTCCCCGACCTTCCACCAACAATCCCCTCCCCAGGATGACGAGGCGGTTGCTGGCGGACCCGACAGGGATGATG
AATAGTGGGCGAGCGGACTG

Product: proteasome-activating nucleotidase

Products: NA

Alternate protein names: PAN; Proteasomal ATPase; Proteasome regulatory ATPase; Proteasome regulatory particle

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MEETGVKDVRDLCEKFLDFKREKERLEELLKEYFKRLEELERKLRAHEEKLRIEARRRKTLEKELEMERDEKAELREELR
RKEVMIEKLRSDLQRMKKPPLIVGTVEEILDDGRVIVKSSTGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSE
KDSRVLAMEVDESPDVSYDDIGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADAT
FIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRMRDATSGDREVQRTLTQLLAEMDGFDPLDDIK
VIAATNRKDILDPALLRPGRFDRHIKIPLPDEEGRYEIFKIHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMA
IREDRDIVTMDDFLKAVDRVMGKKEEESGEFKRAYH

Sequences:

>Translated_436_residues
MEETGVKDVRDLCEKFLDFKREKERLEELLKEYFKRLEELERKLRAHEEKLRIEARRRKTLEKELEMERDEKAELREELR
RKEVMIEKLRSDLQRMKKPPLIVGTVEEILDDGRVIVKSSTGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSE
KDSRVLAMEVDESPDVSYDDIGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADAT
FIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRMRDATSGDREVQRTLTQLLAEMDGFDPLDDIK
VIAATNRKDILDPALLRPGRFDRHIKIPLPDEEGRYEIFKIHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMA
IREDRDIVTMDDFLKAVDRVMGKKEEESGEFKRAYH
>Mature_436_residues
MEETGVKDVRDLCEKFLDFKREKERLEELLKEYFKRLEELERKLRAHEEKLRIEARRRKTLEKELEMERDEKAELREELR
RKEVMIEKLRSDLQRMKKPPLIVGTVEEILDDGRVIVKSSTGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSE
KDSRVLAMEVDESPDVSYDDIGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADAT
FIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRMRDATSGDREVQRTLTQLLAEMDGFDPLDDIK
VIAATNRKDILDPALLRPGRFDRHIKIPLPDEEGRYEIFKIHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMA
IREDRDIVTMDDFLKAVDRVMGKKEEESGEFKRAYH

Specific function: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereb

COG id: COG1222

COG function: function code O; ATP-dependent 26S proteasome regulatory subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family

Homologues:

Organism=Homo sapiens, GI24430151, Length=376, Percent_Identity=52.1276595744681, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI24497435, Length=333, Percent_Identity=55.2552552552552, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI89064750, Length=376, Percent_Identity=48.936170212766, Blast_Score=367, Evalue=1e-102,
Organism=Homo sapiens, GI5729991, Length=376, Percent_Identity=48.936170212766, Blast_Score=367, Evalue=1e-102,
Organism=Homo sapiens, GI195539395, Length=355, Percent_Identity=50.4225352112676, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI24430155, Length=348, Percent_Identity=50.8620689655172, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI21361144, Length=390, Percent_Identity=46.6666666666667, Blast_Score=351, Evalue=7e-97,
Organism=Homo sapiens, GI4506209, Length=338, Percent_Identity=50.887573964497, Blast_Score=341, Evalue=7e-94,
Organism=Homo sapiens, GI6005942, Length=238, Percent_Identity=50.4201680672269, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI300192933, Length=274, Percent_Identity=46.7153284671533, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI157671927, Length=287, Percent_Identity=44.5993031358885, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI4507173, Length=291, Percent_Identity=44.3298969072165, Blast_Score=225, Evalue=7e-59,
Organism=Homo sapiens, GI24497618, Length=242, Percent_Identity=47.5206611570248, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=47.1074380165289, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI7657689, Length=268, Percent_Identity=39.9253731343284, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI21327685, Length=268, Percent_Identity=39.9253731343284, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4505725, Length=228, Percent_Identity=42.1052631578947, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI229577436, Length=293, Percent_Identity=37.2013651877133, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI5901990, Length=276, Percent_Identity=42.0289855072464, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI45643123, Length=249, Percent_Identity=43.3734939759036, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI45643125, Length=249, Percent_Identity=43.3734939759036, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI14149767, Length=241, Percent_Identity=43.9834024896266, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI62177112, Length=241, Percent_Identity=43.9834024896266, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI194018488, Length=283, Percent_Identity=38.86925795053, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI7019569, Length=244, Percent_Identity=39.344262295082, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI226371754, Length=269, Percent_Identity=39.0334572490706, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI17865802, Length=237, Percent_Identity=41.3502109704641, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI31377644, Length=262, Percent_Identity=39.6946564885496, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI11875211, Length=238, Percent_Identity=41.1764705882353, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI40806170, Length=238, Percent_Identity=41.1764705882353, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI31742536, Length=248, Percent_Identity=36.2903225806452, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI112789543, Length=248, Percent_Identity=36.2903225806452, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI156564401, Length=247, Percent_Identity=38.4615384615385, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI310125282, Length=247, Percent_Identity=38.0566801619433, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI310125280, Length=237, Percent_Identity=38.8185654008439, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI40806173, Length=173, Percent_Identity=44.5086705202312, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI64084766, Length=230, Percent_Identity=33.4782608695652, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI116292174, Length=232, Percent_Identity=31.4655172413793, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI40255052, Length=233, Percent_Identity=24.4635193133047, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI75677353, Length=210, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789568, Length=253, Percent_Identity=49.0118577075099, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17554786, Length=360, Percent_Identity=52.5, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25144281, Length=410, Percent_Identity=47.3170731707317, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25144278, Length=410, Percent_Identity=47.3170731707317, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17563250, Length=335, Percent_Identity=51.044776119403, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71987364, Length=376, Percent_Identity=46.8085106382979, Blast_Score=352, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI71987372, Length=376, Percent_Identity=46.8085106382979, Blast_Score=351, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17554784, Length=374, Percent_Identity=48.6631016042781, Blast_Score=343, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI17508701, Length=390, Percent_Identity=46.1538461538462, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17563248, Length=338, Percent_Identity=48.2248520710059, Blast_Score=331, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI17505546, Length=394, Percent_Identity=44.6700507614213, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17531535, Length=238, Percent_Identity=47.0588235294118, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17532375, Length=234, Percent_Identity=47.8632478632479, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17508053, Length=257, Percent_Identity=44.7470817120623, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71994521, Length=271, Percent_Identity=44.280442804428, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17554264, Length=260, Percent_Identity=43.4615384615385, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI115534323, Length=261, Percent_Identity=44.4444444444444, Blast_Score=201, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI193206114, Length=243, Percent_Identity=44.4444444444444, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI133931034, Length=243, Percent_Identity=44.4444444444444, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI193206116, Length=243, Percent_Identity=44.4444444444444, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17537217, Length=298, Percent_Identity=36.9127516778523, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25153574, Length=228, Percent_Identity=39.9122807017544, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=40.2654867256637, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17562804, Length=234, Percent_Identity=39.3162393162393, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI86561515, Length=236, Percent_Identity=41.5254237288136, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25146157, Length=251, Percent_Identity=41.0358565737052, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17560432, Length=250, Percent_Identity=40, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI133901662, Length=294, Percent_Identity=34.6938775510204, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI133901658, Length=300, Percent_Identity=34.3333333333333, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17541224, Length=218, Percent_Identity=38.5321100917431, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17541226, Length=218, Percent_Identity=38.5321100917431, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32563584, Length=239, Percent_Identity=39.3305439330544, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17508421, Length=239, Percent_Identity=39.3305439330544, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17570397, Length=131, Percent_Identity=42.7480916030534, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI32566590, Length=131, Percent_Identity=42.7480916030534, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17533043, Length=160, Percent_Identity=29.375, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320197, Length=331, Percent_Identity=53.4743202416918, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321390, Length=406, Percent_Identity=46.551724137931, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324833, Length=351, Percent_Identity=50.1424501424501, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324691, Length=397, Percent_Identity=45.088161209068, Blast_Score=337, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6320602, Length=356, Percent_Identity=48.0337078651685, Blast_Score=331, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6322704, Length=298, Percent_Identity=52.0134228187919, Blast_Score=328, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6323736, Length=271, Percent_Identity=50.5535055350554, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6320077, Length=238, Percent_Identity=51.6806722689076, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6320854, Length=315, Percent_Identity=42.8571428571429, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6323429, Length=265, Percent_Identity=46.0377358490566, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6321709, Length=235, Percent_Identity=43.4042553191489, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6325281, Length=262, Percent_Identity=42.3664122137405, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6322994, Length=233, Percent_Identity=43.3476394849785, Blast_Score=199, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6324000, Length=260, Percent_Identity=41.5384615384615, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6325431, Length=251, Percent_Identity=40.6374501992032, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319554, Length=292, Percent_Identity=38.013698630137, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6322651, Length=249, Percent_Identity=36.144578313253, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325183, Length=260, Percent_Identity=36.9230769230769, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321465, Length=232, Percent_Identity=40.0862068965517, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6320887, Length=248, Percent_Identity=37.0967741935484, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19920408, Length=360, Percent_Identity=52.2222222222222, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24649446, Length=368, Percent_Identity=51.6304347826087, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI18860063, Length=412, Percent_Identity=48.3009708737864, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI281361487, Length=373, Percent_Identity=49.0616621983914, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24640100, Length=384, Percent_Identity=48.4375, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24651451, Length=326, Percent_Identity=53.3742331288344, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI17738151, Length=389, Percent_Identity=46.7866323907455, Blast_Score=351, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24663015, Length=381, Percent_Identity=46.1942257217848, Blast_Score=350, Evalue=9e-97,
Organism=Drosophila melanogaster, GI17137738, Length=326, Percent_Identity=50.6134969325153, Blast_Score=338, Evalue=6e-93,
Organism=Drosophila melanogaster, GI17137560, Length=237, Percent_Identity=49.3670886075949, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI161076486, Length=237, Percent_Identity=49.3670886075949, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI161076488, Length=237, Percent_Identity=49.3670886075949, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI28574878, Length=255, Percent_Identity=45.0980392156863, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24665814, Length=255, Percent_Identity=45.0980392156863, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19921202, Length=253, Percent_Identity=44.6640316205534, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24660075, Length=233, Percent_Identity=44.6351931330472, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI281365776, Length=233, Percent_Identity=44.6351931330472, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI45552965, Length=233, Percent_Identity=44.6351931330472, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24639391, Length=274, Percent_Identity=44.1605839416058, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24658770, Length=276, Percent_Identity=43.4782608695652, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24652279, Length=194, Percent_Identity=47.4226804123711, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24656820, Length=266, Percent_Identity=38.3458646616541, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24656825, Length=266, Percent_Identity=38.3458646616541, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21355121, Length=225, Percent_Identity=40.4444444444444, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI281363136, Length=238, Percent_Identity=40.7563025210084, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI78707192, Length=238, Percent_Identity=40.7563025210084, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI18859657, Length=237, Percent_Identity=43.0379746835443, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24644145, Length=234, Percent_Identity=42.3076923076923, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281360142, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21357333, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360146, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360138, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360144, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360140, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360136, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24644411, Length=234, Percent_Identity=41.025641025641, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24581396, Length=265, Percent_Identity=38.4905660377359, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28573010, Length=279, Percent_Identity=38.3512544802867, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI20129423, Length=274, Percent_Identity=37.5912408759124, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI17864540, Length=279, Percent_Identity=36.9175627240143, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI28571849, Length=238, Percent_Identity=41.5966386554622, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI28571847, Length=238, Percent_Identity=41.5966386554622, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI20129529, Length=238, Percent_Identity=40.7563025210084, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45554047, Length=173, Percent_Identity=44.5086705202312, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24639486, Length=321, Percent_Identity=31.1526479750779, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573181, Length=159, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAN_METKA (Q8TX03)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614161.1
- ProteinModelPortal:   Q8TX03
- SMR:   Q8TX03
- GeneID:   1476979
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0878
- NMPDR:   fig|190192.1.peg.874
- HOGENOM:   HBG724153
- OMA:   ANHADAT
- ProtClustDB:   PRK03992
- BioCyc:   MKAN190192:MK0878-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00553
- InterPro:   IPR005937
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- SMART:   SM00382
- TIGRFAMs:   TIGR01242

Pfam domain/function: PF00004 AAA

EC number: 3.4.24.- [C]

Molecular weight: Translated: 49768; Mature: 49768

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00674 AAA

Important sites: BINDING 362-362

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETGVKDVRDLCEKFLDFKREKERLEELLKEYFKRLEELERKLRAHEEKLRIEARRRKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKELEMERDEKAELREELRRKEVMIEKLRSDLQRMKKPPLIVGTVEEILDDGRVIVKSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCEEEECC
TGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSEKDSRVLAMEVDESPDVSYDD
CCCHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHH
IGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADAT
CCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
FIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRMRDATSGDREVQ
EEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCHHHHH
RTLTQLLAEMDGFDPLDDIKVIAATNRKDILDPALLRPGRFDRHIKIPLPDEEGRYEIFK
HHHHHHHHHHCCCCCHHHCEEEEECCCHHHCCHHHCCCCCCCCEEECCCCCCCCCEEEEE
IHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMAIREDRDIVTMDDFLKAVDRV
EEECCCCCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
MGKKEEESGEFKRAYH
HCCCCCCCCCHHHCCC
>Mature Secondary Structure
MEETGVKDVRDLCEKFLDFKREKERLEELLKEYFKRLEELERKLRAHEEKLRIEARRRKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKELEMERDEKAELREELRRKEVMIEKLRSDLQRMKKPPLIVGTVEEILDDGRVIVKSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCEEEECC
TGPKFVSNVSPTVDRNELEPGANVALNQQSMAVVDVLPSEKDSRVLAMEVDESPDVSYDD
CCCHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHH
IGGLDEQIREIREVVEKPLKEPELFEKVGVEPPKGVLLYGPPGTGKTLLAKAVANHADAT
CCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
FIRLAAPELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIGARRMRDATSGDREVQ
EEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCHHHHH
RTLTQLLAEMDGFDPLDDIKVIAATNRKDILDPALLRPGRFDRHIKIPLPDEEGRYEIFK
HHHHHHHHHHCCCCCHHHCEEEEECCCHHHCCHHHCCCCCCCCEEECCCCCCCCCEEEEE
IHTRDMNLAEDVDLQKLAKITEGASGADIKAICTEAGMMAIREDRDIVTMDDFLKAVDRV
EEECCCCCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
MGKKEEESGEFKRAYH
HCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014