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The map label for this gene is ydjH [C]

Identifier: 20094253

GI number: 20094253

Start: 777133

End: 778026

Strand: Direct

Name: ydjH [C]

Synonym: MK0817

Alternate gene names: 20094253

Gene position: 777133-778026 (Clockwise)

Preceding gene: 20094252

Following gene: 20094256

Centisome position: 45.85

GC content: 62.08

Gene sequence:

>894_bases
GTGTTGGACGTAGTGGGTCTCGGCGCCCTCAACGTGGACGAGCTTCTGTACATCCCTCGAATGCCCGAACGCGACGATTC
GGTACCTGTCGAACGGAGAGTACGGCGGGGAGGGGGATCCGCGGCGAACACTATCTGTTGGCTCGCCCACCTCGGGAGAG
AAGTGGGGTTCGTCGGGAAAGTCGGCAGCGATGATGCTGGGGATCTCCTACTCCGGGAGTTCGAAGAGTACGGCGTCGAT
ACCTCCAGAGTCGTCAGGGGTGACGGACACAGCGGTACGGCGTTCTGTCTGGTCTCCGGAGACGATAGGAGAATCCTCGT
CGATCCCGGGGTCAACGACGAGCTTCGACCGGATGAGGTCGATCTCGATTACATCCGTAAGGCCCGCGTACTCCACACCA
GCTCGTTCATCGGATTACGATCGGAGACGTCCCTAGAGACCCTGAAGCGGACCATGAAGGCGGTAGCGGACGAGCTGATG
GTGACTTTCTCTCCCGCCACGATGGTCTTGCGTGGCTGGTCCTACTTGGAACCGTACTTCGAAGCCGCCGACGTCGTGTT
CCTCAACGAGACGGAGGCGGTTCACTTGACGGGCGATATCGAGGAGACCCTCAATAGGCTGGCCGAACTCGTGGAAGTAA
CGATCGTCACCCGCGGGTCCGACCCCGCGATCGTCCAAGAAGGGACCGAGATCTCGGAAGTGGCCCCGGAGCCCGTTCCG
GAGGAGGACATCGTAGATCCTACGGGGGCGGGGGATGCCTTCGCGGCCGGATTCATCGAAGGTATTCTACGGGGTGAACC
GGCCGACCGGTGCTGCGAGCGCGGTCACGCGGTAGCCGCCGAGTGTCTGAGAATCGAGGGGTGCCGCCCTCCCACGGAAG
GACGCTCCGAATAG

Upstream 100 bases:

>100_bases
CACGGAGGTTGACGGCGTCGTCAAGGTGTCCGCCGGGAACTTCGGAGGTAAACTCGGCGACTACAGGATTCCGCTGCGGG
AGTGCATTCGGGAGTGAGGA

Downstream 100 bases:

>100_bases
TGGCTCCGAGGATAATCACCTCGGGATGAAGTCCACGAGCTTGTGCACTTGCGGCAACACCCGCACGTCGGCGTTCACCA
GCCCGGCTAACTCCCAAAGA

Product: ribokinase family sugar kinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLDVVGLGALNVDELLYIPRMPERDDSVPVERRVRRGGGSAANTICWLAHLGREVGFVGKVGSDDAGDLLLREFEEYGVD
TSRVVRGDGHSGTAFCLVSGDDRRILVDPGVNDELRPDEVDLDYIRKARVLHTSSFIGLRSETSLETLKRTMKAVADELM
VTFSPATMVLRGWSYLEPYFEAADVVFLNETEAVHLTGDIEETLNRLAELVEVTIVTRGSDPAIVQEGTEISEVAPEPVP
EEDIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAAECLRIEGCRPPTEGRSE

Sequences:

>Translated_297_residues
MLDVVGLGALNVDELLYIPRMPERDDSVPVERRVRRGGGSAANTICWLAHLGREVGFVGKVGSDDAGDLLLREFEEYGVD
TSRVVRGDGHSGTAFCLVSGDDRRILVDPGVNDELRPDEVDLDYIRKARVLHTSSFIGLRSETSLETLKRTMKAVADELM
VTFSPATMVLRGWSYLEPYFEAADVVFLNETEAVHLTGDIEETLNRLAELVEVTIVTRGSDPAIVQEGTEISEVAPEPVP
EEDIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAAECLRIEGCRPPTEGRSE
>Mature_297_residues
MLDVVGLGALNVDELLYIPRMPERDDSVPVERRVRRGGGSAANTICWLAHLGREVGFVGKVGSDDAGDLLLREFEEYGVD
TSRVVRGDGHSGTAFCLVSGDDRRILVDPGVNDELRPDEVDLDYIRKARVLHTSSFIGLRSETSLETLKRTMKAVADELM
VTFSPATMVLRGWSYLEPYFEAADVVFLNETEAVHLTGDIEETLNRLAELVEVTIVTRGSDPAIVQEGTEISEVAPEPVP
EEDIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAAECLRIEGCRPPTEGRSE

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI32484973, Length=309, Percent_Identity=26.537216828479, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI32484975, Length=309, Percent_Identity=26.537216828479, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI11545855, Length=264, Percent_Identity=27.6515151515151, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87081971, Length=301, Percent_Identity=27.5747508305648, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789775, Length=269, Percent_Identity=27.8810408921933, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790193, Length=310, Percent_Identity=23.5483870967742, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17541820, Length=276, Percent_Identity=25.3623188405797, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322565, Length=303, Percent_Identity=27.7227722772277, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24663633, Length=276, Percent_Identity=24.2753623188406, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356339, Length=276, Percent_Identity=24.2753623188406, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571668, Length=284, Percent_Identity=21.1267605633803, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355521, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=24.9180327868852, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583886, Length=310, Percent_Identity=24.8387096774194, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 32342; Mature: 32342

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVVGLGALNVDELLYIPRMPERDDSVPVERRVRRGGGSAANTICWLAHLGREVGFVGK
CCCEEECCCCCHHHEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEC
VGSDDAGDLLLREFEEYGVDTSRVVRGDGHSGTAFCLVSGDDRRILVDPGVNDELRPDEV
CCCCCHHHHHHHHHHHHCCCHHHEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCC
DLDYIRKARVLHTSSFIGLRSETSLETLKRTMKAVADELMVTFSPATMVLRGWSYLEPYF
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHH
EAADVVFLNETEAVHLTGDIEETLNRLAELVEVTIVTRGSDPAIVQEGTEISEVAPEPVP
CCCCEEEECCCCEEEEECCHHHHHHHHHHHHEEEEEECCCCCCEEECCCCHHHCCCCCCC
EEDIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAAECLRIEGCRPPTEGRSE
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLDVVGLGALNVDELLYIPRMPERDDSVPVERRVRRGGGSAANTICWLAHLGREVGFVGK
CCCEEECCCCCHHHEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEC
VGSDDAGDLLLREFEEYGVDTSRVVRGDGHSGTAFCLVSGDDRRILVDPGVNDELRPDEV
CCCCCHHHHHHHHHHHHCCCHHHEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCC
DLDYIRKARVLHTSSFIGLRSETSLETLKRTMKAVADELMVTFSPATMVLRGWSYLEPYF
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHH
EAADVVFLNETEAVHLTGDIEETLNRLAELVEVTIVTRGSDPAIVQEGTEISEVAPEPVP
CCCCEEEECCCCEEEEECCHHHHHHHHHHHHEEEEEECCCCCCEEECCCCHHHCCCCCCC
EEDIVDPTGAGDAFAAGFIEGILRGEPADRCCERGHAVAAECLRIEGCRPPTEGRSE
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]