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The map label for this gene is rfbB [C]

Identifier: 20094161

GI number: 20094161

Start: 692457

End: 693386

Strand: Direct

Name: rfbB [C]

Synonym: MK0724

Alternate gene names: 20094161

Gene position: 692457-693386 (Clockwise)

Preceding gene: 20094160

Following gene: 20094162

Centisome position: 40.85

GC content: 62.04

Gene sequence:

>930_bases
TTGATCCTGGTGACCGGAGGAGCCGGGTTCATAGGTTCGCACGTCGTGGAGGAGCTCGTCGATCGAGGCCACGACGTGGT
GGTTTTGGACAACTTCAGCGTGGGTTGTGAGGAGAACCTCCGTGAGGTCCGGGACGATATCGAGATCGTACGTGCCGACG
TGACGGATCCTAGGGCCGTGGAGCGAACGTTTCGGGAGTACCGACCGGAGGCCGTGATTCACCTGGCCGCCCAGGTCAAC
GTACGCTACTCCATGGAGTCGCCCTTCGTCGACGCCAGGATCAACGCATTGGGTACCCTGAACCTCGTCTCGTTGGCCGC
CGAGCACGACGTCGAGAGATTCGTATACGCGTCCTCGGGTGGGGCGGTGTACGGGGAACCGGAGTACTTACCCGTGGATG
AGGAACATCCCACGCGACCGATATCGAACTACGGCGTCTCGAAGCTCGCAGGTGAGTACTACGTCCGTGTGTACGCCGAG
CGGGACGGGTTCGAGTACGTCATCCTACGATACGCTAACGTTTACGGTCCTCGGCAGGATCCCAGGGGCGAGGCAGGGGT
TATCCCTATCTTCCTATTACGGGCCGCCCGAGGTGAGCCGCTCACGATCTTCGGGGACGGTGAGCAAACCCGTGACTTCG
TTTTCGTCGAGGACGTAGCTCGGGTCACGGCCGAGGCGGTGGAGCGTGGTGATGGTGTGTACAACATAGGTACCGGCCGT
GAGACCTCCGTGAACGACATCGTGAACGCCGTGAAGGCGGTCACAGGGGTCGACGTGGAAGTAGTGTACGAGGATCCGCG
GCCGGGCGAGGTTCGTCGGATATACCTCGACCCGAGCCGCGCCCGGGAGGAGCTGGGGTTCGAGCCACGCGTCGACCTAG
AGGAGGGGATCGAGCGAACCTGGGAGTGGATCCGTCGGAAAATCGCGTAG

Upstream 100 bases:

>100_bases
GCCTGAGTTTCTGGAGAAAGAAGGTCTACTGAGGATTGAGGAATGACCGGCGACTTTATCCTTCCCCAACCCTGGCGCTA
GGGACCTCGGGGATGAGCTG

Downstream 100 bases:

>100_bases
CCCTTTAATCCCCACCTCGGAGGTCCTGGGGGTGCCGAGTTGCCGGACGTTTTCGTCCTGGTCGTCGCCCCGGACAGGTG
CACGGACTGCCGTAAGTGCG

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MILVTGGAGFIGSHVVEELVDRGHDVVVLDNFSVGCEENLREVRDDIEIVRADVTDPRAVERTFREYRPEAVIHLAAQVN
VRYSMESPFVDARINALGTLNLVSLAAEHDVERFVYASSGGAVYGEPEYLPVDEEHPTRPISNYGVSKLAGEYYVRVYAE
RDGFEYVILRYANVYGPRQDPRGEAGVIPIFLLRAARGEPLTIFGDGEQTRDFVFVEDVARVTAEAVERGDGVYNIGTGR
ETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERTWEWIRRKIA

Sequences:

>Translated_309_residues
MILVTGGAGFIGSHVVEELVDRGHDVVVLDNFSVGCEENLREVRDDIEIVRADVTDPRAVERTFREYRPEAVIHLAAQVN
VRYSMESPFVDARINALGTLNLVSLAAEHDVERFVYASSGGAVYGEPEYLPVDEEHPTRPISNYGVSKLAGEYYVRVYAE
RDGFEYVILRYANVYGPRQDPRGEAGVIPIFLLRAARGEPLTIFGDGEQTRDFVFVEDVARVTAEAVERGDGVYNIGTGR
ETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERTWEWIRRKIA
>Mature_309_residues
MILVTGGAGFIGSHVVEELVDRGHDVVVLDNFSVGCEENLREVRDDIEIVRADVTDPRAVERTFREYRPEAVIHLAAQVN
VRYSMESPFVDARINALGTLNLVSLAAEHDVERFVYASSGGAVYGEPEYLPVDEEHPTRPISNYGVSKLAGEYYVRVYAE
RDGFEYVILRYANVYGPRQDPRGEAGVIPIFLLRAARGEPLTIFGDGEQTRDFVFVEDVARVTAEAVERGDGVYNIGTGR
ETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERTWEWIRRKIA

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=35.0148367952522, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=35.0148367952522, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=35.0148367952522, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI7657641, Length=318, Percent_Identity=34.2767295597484, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=30.7936507936508, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4504031, Length=333, Percent_Identity=24.3243243243243, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788353, Length=335, Percent_Identity=33.134328358209, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=31.7365269461078, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI48994969, Length=331, Percent_Identity=30.5135951661631, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790049, Length=322, Percent_Identity=29.5031055900621, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788365, Length=332, Percent_Identity=24.3975903614458, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788366, Length=343, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=336, Percent_Identity=35.1190476190476, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71982038, Length=338, Percent_Identity=35.207100591716, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=29.4303797468354, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17568069, Length=327, Percent_Identity=28.4403669724771, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI115532424, Length=322, Percent_Identity=27.0186335403727, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17507723, Length=337, Percent_Identity=25.5192878338279, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17554428, Length=324, Percent_Identity=26.2345679012346, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133901786, Length=337, Percent_Identity=25.5192878338279, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133901788, Length=337, Percent_Identity=25.5192878338279, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17539422, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133901790, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539424, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=336, Percent_Identity=31.547619047619, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321437, Length=349, Percent_Identity=22.6361031518625, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923002, Length=335, Percent_Identity=33.7313432835821, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=30.379746835443, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34650; Mature: 34650

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGFIGSHVVEELVDRGHDVVVLDNFSVGCEENLREVRDDIEIVRADVTDPRAV
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCHHH
ERTFREYRPEAVIHLAAQVNVRYSMESPFVDARINALGTLNLVSLAAEHDVERFVYASSG
HHHHHHHCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEECCC
GAVYGEPEYLPVDEEHPTRPISNYGVSKLAGEYYVRVYAERDGFEYVILRYANVYGPRQD
CEECCCCCCCCCCCCCCCCCCHHCCHHHHCCEEEEEEEEECCCCEEEEEEEHHHCCCCCC
PRGEAGVIPIFLLRAARGEPLTIFGDGEQTRDFVFVEDVARVTAEAVERGDGVYNIGTGR
CCCCCCCHHHHEEECCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCCC
ETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERT
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHH
WEWIRRKIA
HHHHHHHCC
>Mature Secondary Structure
MILVTGGAGFIGSHVVEELVDRGHDVVVLDNFSVGCEENLREVRDDIEIVRADVTDPRAV
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCHHH
ERTFREYRPEAVIHLAAQVNVRYSMESPFVDARINALGTLNLVSLAAEHDVERFVYASSG
HHHHHHHCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEECCC
GAVYGEPEYLPVDEEHPTRPISNYGVSKLAGEYYVRVYAERDGFEYVILRYANVYGPRQD
CEECCCCCCCCCCCCCCCCCCHHCCHHHHCCEEEEEEEEECCCCEEEEEEEHHHCCCCCC
PRGEAGVIPIFLLRAARGEPLTIFGDGEQTRDFVFVEDVARVTAEAVERGDGVYNIGTGR
CCCCCCCHHHHEEECCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCCC
ETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIYLDPSRAREELGFEPRVDLEEGIERT
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHH
WEWIRRKIA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]