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The map label for this gene is MtrC

Identifier: 20094096

GI number: 20094096

Start: 618120

End: 618932

Strand: Direct

Name: MtrC

Synonym: MK0658

Alternate gene names: 20094096

Gene position: 618120-618932 (Clockwise)

Preceding gene: 20094095

Following gene: 20094097

Centisome position: 36.47

GC content: 65.93

Gene sequence:

>813_bases
TTGATCCTGCGTACACTCCTGATCTCCGCCGTAGCACCGGGTGGCGAGGAGGAAGAGGTAGAGGTCGCCGTAGCGATCTC
GCCCTTGAAACTGATGACGGCCGGCCTGATCTGCGGAATACTCGGTACCGCTTTCGCCTGGGTTCACCCGTTGATCCCGG
CGTTGGCAGTGATTCCGGTAGTGGTCTGGGGTGCCGACGCGGTTAGGAGGGTCGCGGGCTACGGACTGGGTACCGGAGTG
CCTTCCATCGGTTTCATGGGACTCGGTGGCGGATCCGTCGCCGCGATCCTGGCGGCGGCGCTGTCCGGTAACACCGTGCC
CGCATGGGCGGCGGCCATCATCGGAACAGTCATCGGCGCCGTCGTCGGGGCGCTGCTCGGCGTCCTGGACCGCCGCGTGA
TCAAGATGAAGATCCCGGTGATGGAGCGCTGCAGCACCGAGATCGTGGCGTCCGGAACGCTGGCGCTGATCTGTCTCATG
GCAGCCGTCGCCGGCGACTTCACGTGGTCCGCGGTGTACTCCAAGGTGATCGCGACGGGTCTCATCGCCGTCCTCTGGGC
GATCTGCGCGATCTCGCTGCTGCACCCGTTCAACGCGTGCCTCGGACCCAGTGAGACGCAGGAGCGGACGCTGTGGCTGG
GCGCGGAGTGCGGCTCGCTCTGCACGGTCGTGGCGGGACTAGCGACGGCCAACCCGGTGGTACTACTGGCCGGTGCGGCC
GCTTGGCTGATCACCTTCTGGAAGTTCTGGGAGCTGACGAAGCGCGACGCCGCGGACGTAGTGTGGACTGGAATCGTGCC
CAAGGGTGAGTAA

Upstream 100 bases:

>100_bases
CTACCGAAGGCGGTAGTATGCTCCCTAGTATTCGGTATAGTAGCGTCCGTGATCGCGTATTACCTCTCGACCCTCATGTA
ACGGGGGAGTGTGAGGAACC

Downstream 100 bases:

>100_bases
GGGGTGAACGACCTTGGCGATCGTGCTCATCGACCCGGAGAGCCAGATCGCGATGGACGCCGTGACCGGAGCCGTGGCGG
AGTGGAGCGAGGACGTGGTG

Product: tetrahydromethanopterin S-methyltransferase subunit C

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MILRTLLISAVAPGGEEEEVEVAVAISPLKLMTAGLICGILGTAFAWVHPLIPALAVIPVVVWGADAVRRVAGYGLGTGV
PSIGFMGLGGGSVAAILAAALSGNTVPAWAAAIIGTVIGAVVGALLGVLDRRVIKMKIPVMERCSTEIVASGTLALICLM
AAVAGDFTWSAVYSKVIATGLIAVLWAICAISLLHPFNACLGPSETQERTLWLGAECGSLCTVVAGLATANPVVLLAGAA
AWLITFWKFWELTKRDAADVVWTGIVPKGE

Sequences:

>Translated_270_residues
MILRTLLISAVAPGGEEEEVEVAVAISPLKLMTAGLICGILGTAFAWVHPLIPALAVIPVVVWGADAVRRVAGYGLGTGV
PSIGFMGLGGGSVAAILAAALSGNTVPAWAAAIIGTVIGAVVGALLGVLDRRVIKMKIPVMERCSTEIVASGTLALICLM
AAVAGDFTWSAVYSKVIATGLIAVLWAICAISLLHPFNACLGPSETQERTLWLGAECGSLCTVVAGLATANPVVLLAGAA
AWLITFWKFWELTKRDAADVVWTGIVPKGE
>Mature_270_residues
MILRTLLISAVAPGGEEEEVEVAVAISPLKLMTAGLICGILGTAFAWVHPLIPALAVIPVVVWGADAVRRVAGYGLGTGV
PSIGFMGLGGGSVAAILAAALSGNTVPAWAAAIIGTVIGAVVGALLGVLDRRVIKMKIPVMERCSTEIVASGTLALICLM
AAVAGDFTWSAVYSKVIATGLIAVLWAICAISLLHPFNACLGPSETQERTLWLGAECGSLCTVVAGLATANPVVLLAGAA
AWLITFWKFWELTKRDAADVVWTGIVPKGE

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4061

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit C

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRC_METKA (O32865)

Other databases:

- EMBL:   Y14428
- EMBL:   AE009439
- RefSeq:   NP_613943.1
- ProteinModelPortal:   O32865
- GeneID:   1476759
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0658
- NMPDR:   fig|190192.1.peg.656
- HOGENOM:   HBG542041
- OMA:   ILHPFNA
- ProtClustDB:   PRK01030
- BioCyc:   MKAN190192:MK0658-MONOMER
- BRENDA:   2.1.1.86
- GO:   GO:0015948
- HAMAP:   MF_01096
- InterPro:   IPR005865
- PIRSF:   PIRSF006530
- ProDom:   PD013899
- TIGRFAMs:   TIGR01148

Pfam domain/function: PF04211 MtrC

EC number: =2.1.1.86

Molecular weight: Translated: 27666; Mature: 27666

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xca74b50)-; HASH(0xc590b34)-; HASH(0xc402778)-; HASH(0xd1b1584)-; HASH(0xd2754c8)-; HASH(0xd135ae8)-; HASH(0xd3d0380)-;

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILRTLLISAVAPGGEEEEVEVAVAISPLKLMTAGLICGILGTAFAWVHPLIPALAVIPV
CHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVWGADAVRRVAGYGLGTGVPSIGFMGLGGGSVAAILAAALSGNTVPAWAAAIIGTVIGA
HHHCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VVGALLGVLDRRVIKMKIPVMERCSTEIVASGTLALICLMAAVAGDFTWSAVYSKVIATG
HHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIAVLWAICAISLLHPFNACLGPSETQERTLWLGAECGSLCTVVAGLATANPVVLLAGAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
AWLITFWKFWELTKRDAADVVWTGIVPKGE
HHHHHHHHHHHHHHHCCCCEEEECCCCCCH
>Mature Secondary Structure
MILRTLLISAVAPGGEEEEVEVAVAISPLKLMTAGLICGILGTAFAWVHPLIPALAVIPV
CHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVWGADAVRRVAGYGLGTGVPSIGFMGLGGGSVAAILAAALSGNTVPAWAAAIIGTVIGA
HHHCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VVGALLGVLDRRVIKMKIPVMERCSTEIVASGTLALICLMAAVAGDFTWSAVYSKVIATG
HHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIAVLWAICAISLLHPFNACLGPSETQERTLWLGAECGSLCTVVAGLATANPVVLLAGAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
AWLITFWKFWELTKRDAADVVWTGIVPKGE
HHHHHHHHHHHHHHHCCCCEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9461302; 11930014