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The map label for this gene is TatD [C]

Identifier: 20093984

GI number: 20093984

Start: 509917

End: 510690

Strand: Direct

Name: TatD [C]

Synonym: MK0546

Alternate gene names: 20093984

Gene position: 509917-510690 (Clockwise)

Preceding gene: 20093982

Following gene: 20093985

Centisome position: 30.08

GC content: 59.43

Gene sequence:

>774_bases
TTGAAGAAACCCGTCGACGCTCACTGTCATCTTTGCTTCAAATACTTCAAAGGCGAGGAAGACGAAGTGGTAGAACGGTC
ACGGAAGAAGGTGTTACGCGTGTACGACTGCGGGGCTACCCCTGGAACCGCACGGCGAACCCTGGAGTTAGCGGAGAGAT
TCGAGGGGTTCGTGTTCTCCACGATCGGGCTCCATCCCCCACGAGCGCCGAGGATGCAGCAGAGCGTCATCGATGACGTG
GTCCGAATTATCCGTGAGCACGCCGACAGGATCGCGGCAATTGGAGAGATAGGTCTTGACTACCACTACGTGAAGGAACC
CGGAGAGCGCAGGAGGATGCGAGAGGTCTTCGAGAGGTTCCTGAAGCTCGCGGAAGAGCTCGACAAGCCGGTAGTGATTC
ACGCCAGGGATGCGGAAGAGCACGCCCTCGAGGTCCTAGAGGACTACGACGTAGTCGCCATGTTCCACTGCTACGACGGA
CCGGCCGAGCTCGCCCGGCGTATCGCGGACGCCGGCCACTACGTTTCACTGTCGACGATTCACGTCATTCGTGGACCGAA
GGATGAGAGAACGCGGGAACTGCTGGAGACTGTACCGTTGGAAGCGGCACTTACGGAGACGGACAGCCCATACCTGTCAC
CGGTGCGGGGAGAACGCAACGAGCCTCGGAACGTGTGGAGGGTAATAGAGTTGCTCGCGCGGGTGAAGGGAGTCCCCGTC
GGCGAGGTAGTTGAGACCACGGCGCGTAACGCGCTGGAGTTCTACGATCTATGA

Upstream 100 bases:

>100_bases
GATGATGGAGGCCCTCCCTAGCCGAGGGAACCGATGAGGATCCAGCCCTTTCGCCGACCCCCCAGTGAAATGCTGTCCGG
AGGAGAACGGGGGGACCCGC

Downstream 100 bases:

>100_bases
GGAGAAAATTTTAAATATAACCCACCTAGCGTGCGGTTGTGGCGGCGGCCACAGCGGCCGGGGCCACACCCGGGCCACAT
CTCGAACCCGGAAGTTAAGC

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKKPVDAHCHLCFKYFKGEEDEVVERSRKKVLRVYDCGATPGTARRTLELAERFEGFVFSTIGLHPPRAPRMQQSVIDDV
VRIIREHADRIAAIGEIGLDYHYVKEPGERRRMREVFERFLKLAEELDKPVVIHARDAEEHALEVLEDYDVVAMFHCYDG
PAELARRIADAGHYVSLSTIHVIRGPKDERTRELLETVPLEAALTETDSPYLSPVRGERNEPRNVWRVIELLARVKGVPV
GEVVETTARNALEFYDL

Sequences:

>Translated_257_residues
MKKPVDAHCHLCFKYFKGEEDEVVERSRKKVLRVYDCGATPGTARRTLELAERFEGFVFSTIGLHPPRAPRMQQSVIDDV
VRIIREHADRIAAIGEIGLDYHYVKEPGERRRMREVFERFLKLAEELDKPVVIHARDAEEHALEVLEDYDVVAMFHCYDG
PAELARRIADAGHYVSLSTIHVIRGPKDERTRELLETVPLEAALTETDSPYLSPVRGERNEPRNVWRVIELLARVKGVPV
GEVVETTARNALEFYDL
>Mature_257_residues
MKKPVDAHCHLCFKYFKGEEDEVVERSRKKVLRVYDCGATPGTARRTLELAERFEGFVFSTIGLHPPRAPRMQQSVIDDV
VRIIREHADRIAAIGEIGLDYHYVKEPGERRRMREVFERFLKLAEELDKPVVIHARDAEEHALEVLEDYDVVAMFHCYDG
PAELARRIADAGHYVSLSTIHVIRGPKDERTRELLETVPLEAALTETDSPYLSPVRGERNEPRNVWRVIELLARVKGVPV
GEVVETTARNALEFYDL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=261, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI110349734, Length=261, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI226061853, Length=265, Percent_Identity=32.8301886792453, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=30.9803921568627, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI226061595, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=22.8915662650602, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI14042943, Length=249, Percent_Identity=22.8915662650602, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI225903424, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=34.375, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=25.5813953488372, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI48994985, Length=269, Percent_Identity=27.5092936802974, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71980746, Length=257, Percent_Identity=27.2373540856031, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=25, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17543026, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29500; Mature: 29500

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPVDAHCHLCFKYFKGEEDEVVERSRKKVLRVYDCGATPGTARRTLELAERFEGFVFS
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
TIGLHPPRAPRMQQSVIDDVVRIIREHADRIAAIGEIGLDYHYVKEPGERRRMREVFERF
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
LKLAEELDKPVVIHARDAEEHALEVLEDYDVVAMFHCYDGPAELARRIADAGHYVSLSTI
HHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEE
HVIRGPKDERTRELLETVPLEAALTETDSPYLSPVRGERNEPRNVWRVIELLARVKGVPV
EEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
GEVVETTARNALEFYDL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKPVDAHCHLCFKYFKGEEDEVVERSRKKVLRVYDCGATPGTARRTLELAERFEGFVFS
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
TIGLHPPRAPRMQQSVIDDVVRIIREHADRIAAIGEIGLDYHYVKEPGERRRMREVFERF
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
LKLAEELDKPVVIHARDAEEHALEVLEDYDVVAMFHCYDGPAELARRIADAGHYVSLSTI
HHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEE
HVIRGPKDERTRELLETVPLEAALTETDSPYLSPVRGERNEPRNVWRVIELLARVKGVPV
EEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
GEVVETTARNALEFYDL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]