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The map label for this gene is argF [H]

Identifier: 197119998

GI number: 197119998

Start: 4161008

End: 4161919

Strand: Direct

Name: argF [H]

Synonym: Gbem_3637

Alternate gene names: 197119998

Gene position: 4161008-4161919 (Clockwise)

Preceding gene: 197119997

Following gene: 197119999

Centisome position: 90.16

GC content: 61.4

Gene sequence:

>912_bases
ATGAAAAGAGACTTCCTCGCGCTGAGCCAGTTCTCGAAGGCTGAACTGGACGCGATCTTCCTGTTGACCAAAGAGCTCAA
GGAAAAGCAAAAAAAGGGCGTCGAGCACCACCTTTTGAAAGGGAAGTCCCTCGCCATGATCTTCGAGAAGTCCTCCACCC
GCACCAGGCTCTCCTTCGAGATCGGGATGTACCAGCTGGGAGGGCACCCGCTCTTCATCTCCAGCAAGGACTCGCAGATG
GGTCGCGGCGAGCCGATCAAGGACACCGCCCGCGTCATGGCGCGCTACTGCGACGGCGTCATGATCCGTACCTTCGCCCA
GGAGACGGTGGAAGAGTTCGCCAAATACGCCTCCGTCCCCATCATCAACGGGCTCACCGACCTGCACCACCCCTGCCAGA
TCATGGCCGACATCTTCACCGTGATCGAGCACAGGGGGGGGTACCAGGGGCTCAAGTTCGCCTGGATCGGCGACGGAAAC
AACATGGCCAACAGCTGGATCGAAGCCGCGGCCATCTTCGGCTTCGACCTGACCCTCGCCTGCCCCGAGGGGTACGACCC
GAACCCGCAGGTGCTTGAGTGGGCGCAAAAGCACGCCAGCTCCAAGATCGTCGTCACCCGCGACCCGAAAGTCGCCGCCC
AGGACGCGGACGTCTTGAACACCGACGTCTGGGCTAGCATGGGACAGGAAGAGGAGCAGAAGATCAGGGAGAAGGCTTTC
GCCGGATTCCAGCTGAACGAGGAGCTCCTCGATCTCGCCAAGGGGAACGCCATGGTGCTGCACTGCCTGCCGGCCCACCG
CGGCGAGGAGATCACCGACGACGTCATCGAAGGCCCCCACTCCGCGGTCTGGGACGAGGCGGAGAACCGGCTGCACGTGC
AAAAGGCCATCATGGCCATTTTGATGAAATAA

Upstream 100 bases:

>100_bases
ACTTTAACTGCTCCCTCCCCCTCCCTTGACGGGAGGGGGAAGTTGATATGAGGTGCCGGCTCGGCCGGCACCATTAAAAC
TAGAAACGAGACCACACCAC

Downstream 100 bases:

>100_bases
TCGGACCGATCCAAACGATCCGACCGATCACACAAAGATAAGGAGAACCCATGGCAAAGAAAGAAGTGAAAAAGATCGTC
CTCGCCTACTCCGGCGGGCT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKRDFLALSQFSKAELDAIFLLTKELKEKQKKGVEHHLLKGKSLAMIFEKSSTRTRLSFEIGMYQLGGHPLFISSKDSQM
GRGEPIKDTARVMARYCDGVMIRTFAQETVEEFAKYASVPIINGLTDLHHPCQIMADIFTVIEHRGGYQGLKFAWIGDGN
NMANSWIEAAAIFGFDLTLACPEGYDPNPQVLEWAQKHASSKIVVTRDPKVAAQDADVLNTDVWASMGQEEEQKIREKAF
AGFQLNEELLDLAKGNAMVLHCLPAHRGEEITDDVIEGPHSAVWDEAENRLHVQKAIMAILMK

Sequences:

>Translated_303_residues
MKRDFLALSQFSKAELDAIFLLTKELKEKQKKGVEHHLLKGKSLAMIFEKSSTRTRLSFEIGMYQLGGHPLFISSKDSQM
GRGEPIKDTARVMARYCDGVMIRTFAQETVEEFAKYASVPIINGLTDLHHPCQIMADIFTVIEHRGGYQGLKFAWIGDGN
NMANSWIEAAAIFGFDLTLACPEGYDPNPQVLEWAQKHASSKIVVTRDPKVAAQDADVLNTDVWASMGQEEEQKIREKAF
AGFQLNEELLDLAKGNAMVLHCLPAHRGEEITDDVIEGPHSAVWDEAENRLHVQKAIMAILMK
>Mature_303_residues
MKRDFLALSQFSKAELDAIFLLTKELKEKQKKGVEHHLLKGKSLAMIFEKSSTRTRLSFEIGMYQLGGHPLFISSKDSQM
GRGEPIKDTARVMARYCDGVMIRTFAQETVEEFAKYASVPIINGLTDLHHPCQIMADIFTVIEHRGGYQGLKFAWIGDGN
NMANSWIEAAAIFGFDLTLACPEGYDPNPQVLEWAQKHASSKIVVTRDPKVAAQDADVLNTDVWASMGQEEEQKIREKAF
AGFQLNEELLDLAKGNAMVLHCLPAHRGEEITDDVIEGPHSAVWDEAENRLHVQKAIMAILMK

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=45.3947368421053, Blast_Score=267, Evalue=9e-72,
Organism=Homo sapiens, GI18105007, Length=305, Percent_Identity=27.2131147540984, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1786469, Length=324, Percent_Identity=40.1234567901235, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1790703, Length=324, Percent_Identity=40.7407407407407, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI2367364, Length=312, Percent_Identity=29.1666666666667, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI48994908, Length=358, Percent_Identity=24.8603351955307, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193204318, Length=330, Percent_Identity=26.3636363636364, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322373, Length=279, Percent_Identity=37.2759856630824, Blast_Score=196, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322331, Length=308, Percent_Identity=26.6233766233766, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24642586, Length=308, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 33932; Mature: 33932

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDFLALSQFSKAELDAIFLLTKELKEKQKKGVEHHLLKGKSLAMIFEKSSTRTRLSFE
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCEEEEEE
IGMYQLGGHPLFISSKDSQMGRGEPIKDTARVMARYCDGVMIRTFAQETVEEFAKYASVP
ECEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
IINGLTDLHHPCQIMADIFTVIEHRGGYQGLKFAWIGDGNNMANSWIEAAAIFGFDLTLA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCEEEEEE
CPEGYDPNPQVLEWAQKHASSKIVVTRDPKVAAQDADVLNTDVWASMGQEEEQKIREKAF
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AGFQLNEELLDLAKGNAMVLHCLPAHRGEEITDDVIEGPHSAVWDEAENRLHVQKAIMAI
CCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LMK
HCC
>Mature Secondary Structure
MKRDFLALSQFSKAELDAIFLLTKELKEKQKKGVEHHLLKGKSLAMIFEKSSTRTRLSFE
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCEEEEEE
IGMYQLGGHPLFISSKDSQMGRGEPIKDTARVMARYCDGVMIRTFAQETVEEFAKYASVP
ECEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
IINGLTDLHHPCQIMADIFTVIEHRGGYQGLKFAWIGDGNNMANSWIEAAAIFGFDLTLA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCEEEEEE
CPEGYDPNPQVLEWAQKHASSKIVVTRDPKVAAQDADVLNTDVWASMGQEEEQKIREKAF
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
AGFQLNEELLDLAKGNAMVLHCLPAHRGEEITDDVIEGPHSAVWDEAENRLHVQKAIMAI
CCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LMK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA