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The map label for this gene is stc [H]

Identifier: 197119938

GI number: 197119938

Start: 4092206

End: 4093858

Strand: Direct

Name: stc [H]

Synonym: Gbem_3577

Alternate gene names: 197119938

Gene position: 4092206-4093858 (Clockwise)

Preceding gene: 197119932

Following gene: 197119940

Centisome position: 88.67

GC content: 60.8

Gene sequence:

>1653_bases
ATGGATACACCTGCCACTGCAGCAAAGACGAGGAAGGCGGAGTATTGCCGCTGCGGTGTAATCTTTTGCGATGAAGCCGG
CCGCATTACCGCCGCCAGCAAGGATTACATCTGGCCAGCCGGCATGAAGGCAAAGGCGGGGGAGGATCTTCCCGCCGAGC
TGCTCCTACTTCATGCGGGGGAATGGGTCTTTCTGGAGAAAGATTGGTTCGTGCAGGCGGAGGGAAAGGGACGGGTGGAG
ATGCTGCTCTTCCGCAGGATCAGGGCCGCGGACCAGGTCCTTGGGCCCTACGGCGACTCTGCGATTAACGAGGGGATGGT
CCACATGGTTCTGAATAACCCGTACGAGGGTTTGACCTCCGTGGACCGGGAGGGCAAGGTCACCTTCCTGAGCCCGGTGA
ACGAAAAGTGGCTGGGGCTGGAAGAGGGAGGAGGGATGGGGCTGCCGCTCTCTTCGTTCGCTCCTGGAAGCCGGCTTGCC
GAGATCGCCCTTACCGGGGTCTCCGACACCACCCAAGTGGTCGATATTCAAGGGCAGACCAAGGTGACGGTCAACCTCCC
CATCAAGAAAGGGCAGAAGGTGATCGGGGCGGTAGGGCGCATACTGTTCAAAAGTACCGACCAGATCGACAAGCTGGCCA
ACCGTATCCGCACCATGGAACTGAAGGTCGAACGGTACGAGACCCTGCTCGACGAGATGCGGGGCAACCGCTACAACTTC
GACAAGATCCTCACCAACAACAAGCCCATGCGGGCCCTGATCGACCAGGCACGCCGGGTCGCCGACTCCTCGGCGACGGT
ACTGATCCTCGGGGAGAGCGGTACGGGCAAGGAGCTTTTCGCACAGGCCCTGCACGAGGGATCGGCCCGCAGGAGAGGGC
CCTTCGTGGCGATCAACTGCAGCGCCCTCCCTCACGACCTTATCGAATCCGAACTGTTCGGTTATGATGAGGGTGCCTTC
AGCGGGGCGAAACGGAAGGGGAAGCCGGGAAAATTCGAGTTGGCCTGCGGGGGGACGCTCTTTCTCGACGAGATCGGCGA
GCTGCCACTGGAGAGCCAGGCGAAACTTCTCCGCGTTCTGGAAGAACGCAAGATCGACCGGCTTGGCAGCACCTCGCCCA
TCTCAGTAGATTTCCGTCTGTTGGCCGCAACAAACCGCAACCTGGAAAGCTCGGTGAACACAGGGAAGTTCCGCAGCGAC
CTCTTCTACCGCATCAACGAATTTCCCATCGAGCTTCCCCCGTTGCGGTCGCGCCGGGATGACATCCCCCTCCTGAGCAA
GCACTTTCTTGAGGAGATCACCCACAAGGAAAAGCTTCCCATGCTGACCATCTCCGAGGAGGCGAAAGCCGCCCTGATGC
GCTACGACTGGCCAGGGAACGTGAGGGAGTTGCGGGGGCTGATGAGGCAAATGACCTGGAAAACCCAGGGACATACCATC
GAGCTCCACCACCTGCCTGCCGCGTTCACCGAAGAAGGAACGATCATCGGGGCCTCCGGCTCCCTAGAGGAACAGCTGGC
GAGCGCCGAGCGGGCCATCATCGAAACAGCTCTCGAAACCGCCCAGGGGAACCGTGCCCTCACGGCCAGGATGCTCGGCA
TCCACCGCACCGCGCTGTACAAGAAGATGACCAGACTCGGCATGGAGATGTGA

Upstream 100 bases:

>100_bases
TGTGTAGCCGAGCGGAAACATCCGAAGCGAGCAGATGACTCGATAGCCTGATCAAACCGACAGATCCCAGCGGCGTACCC
GCAAGGAGACATGTAGACCT

Downstream 100 bases:

>100_bases
GTCGCAACTTCAGGCAGTCTCTGCGGCCACCGTTTTGGCATCAGGCAGGGCCTGCATCCTGTTGATGACTCGCTTGCCGA
TCTGCACAGCCGGCTTCTCG

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MDTPATAAKTRKAEYCRCGVIFCDEAGRITAASKDYIWPAGMKAKAGEDLPAELLLLHAGEWVFLEKDWFVQAEGKGRVE
MLLFRRIRAADQVLGPYGDSAINEGMVHMVLNNPYEGLTSVDREGKVTFLSPVNEKWLGLEEGGGMGLPLSSFAPGSRLA
EIALTGVSDTTQVVDIQGQTKVTVNLPIKKGQKVIGAVGRILFKSTDQIDKLANRIRTMELKVERYETLLDEMRGNRYNF
DKILTNNKPMRALIDQARRVADSSATVLILGESGTGKELFAQALHEGSARRRGPFVAINCSALPHDLIESELFGYDEGAF
SGAKRKGKPGKFELACGGTLFLDEIGELPLESQAKLLRVLEERKIDRLGSTSPISVDFRLLAATNRNLESSVNTGKFRSD
LFYRINEFPIELPPLRSRRDDIPLLSKHFLEEITHKEKLPMLTISEEAKAALMRYDWPGNVRELRGLMRQMTWKTQGHTI
ELHHLPAAFTEEGTIIGASGSLEEQLASAERAIIETALETAQGNRALTARMLGIHRTALYKKMTRLGMEM

Sequences:

>Translated_550_residues
MDTPATAAKTRKAEYCRCGVIFCDEAGRITAASKDYIWPAGMKAKAGEDLPAELLLLHAGEWVFLEKDWFVQAEGKGRVE
MLLFRRIRAADQVLGPYGDSAINEGMVHMVLNNPYEGLTSVDREGKVTFLSPVNEKWLGLEEGGGMGLPLSSFAPGSRLA
EIALTGVSDTTQVVDIQGQTKVTVNLPIKKGQKVIGAVGRILFKSTDQIDKLANRIRTMELKVERYETLLDEMRGNRYNF
DKILTNNKPMRALIDQARRVADSSATVLILGESGTGKELFAQALHEGSARRRGPFVAINCSALPHDLIESELFGYDEGAF
SGAKRKGKPGKFELACGGTLFLDEIGELPLESQAKLLRVLEERKIDRLGSTSPISVDFRLLAATNRNLESSVNTGKFRSD
LFYRINEFPIELPPLRSRRDDIPLLSKHFLEEITHKEKLPMLTISEEAKAALMRYDWPGNVRELRGLMRQMTWKTQGHTI
ELHHLPAAFTEEGTIIGASGSLEEQLASAERAIIETALETAQGNRALTARMLGIHRTALYKKMTRLGMEM
>Mature_550_residues
MDTPATAAKTRKAEYCRCGVIFCDEAGRITAASKDYIWPAGMKAKAGEDLPAELLLLHAGEWVFLEKDWFVQAEGKGRVE
MLLFRRIRAADQVLGPYGDSAINEGMVHMVLNNPYEGLTSVDREGKVTFLSPVNEKWLGLEEGGGMGLPLSSFAPGSRLA
EIALTGVSDTTQVVDIQGQTKVTVNLPIKKGQKVIGAVGRILFKSTDQIDKLANRIRTMELKVERYETLLDEMRGNRYNF
DKILTNNKPMRALIDQARRVADSSATVLILGESGTGKELFAQALHEGSARRRGPFVAINCSALPHDLIESELFGYDEGAF
SGAKRKGKPGKFELACGGTLFLDEIGELPLESQAKLLRVLEERKIDRLGSTSPISVDFRLLAATNRNLESSVNTGKFRSD
LFYRINEFPIELPPLRSRRDDIPLLSKHFLEEITHKEKLPMLTISEEAKAALMRYDWPGNVRELRGLMRQMTWKTQGHTI
ELHHLPAAFTEEGTIIGASGSLEEQLASAERAIIETALETAQGNRALTARMLGIHRTALYKKMTRLGMEM

Specific function: Required For Induction Of Expression Of The Hydrogenase- 4 Structural Genes. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=45.9627329192547, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1788550, Length=319, Percent_Identity=44.2006269592476, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1790437, Length=296, Percent_Identity=45.6081081081081, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI1790299, Length=315, Percent_Identity=44.1269841269841, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789087, Length=376, Percent_Identity=40.4255319148936, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1789233, Length=449, Percent_Identity=35.6347438752784, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1788905, Length=305, Percent_Identity=42.9508196721311, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1786524, Length=338, Percent_Identity=39.6449704142012, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=400, Percent_Identity=37.5, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=36.4820846905537, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=35.1437699680511, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI87081858, Length=332, Percent_Identity=33.7349397590361, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789828, Length=285, Percent_Identity=37.1929824561403, Blast_Score=139, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 61032; Mature: 61032

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPATAAKTRKAEYCRCGVIFCDEAGRITAASKDYIWPAGMKAKAGEDLPAELLLLHAG
CCCCCCHHHHCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHEEEEECC
EWVFLEKDWFVQAEGKGRVEMLLFRRIRAADQVLGPYGDSAINEGMVHMVLNNPYEGLTS
CEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCHHHC
VDREGKVTFLSPVNEKWLGLEEGGGMGLPLSSFAPGSRLAEIALTGVSDTTQVVDIQGQT
CCCCCCEEEECCCCCHHCCEECCCCCCCCHHCCCCCCCEEEEEEECCCCCCEEEEECCCE
KVTVNLPIKKGQKVIGAVGRILFKSTDQIDKLANRIRTMELKVERYETLLDEMRGNRYNF
EEEEECCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DKILTNNKPMRALIDQARRVADSSATVLILGESGTGKELFAQALHEGSARRRGPFVAINC
HHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEC
SALPHDLIESELFGYDEGAFSGAKRKGKPGKFELACGGTLFLDEIGELPLESQAKLLRVL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEEHHHHCCCCCHHHHHHHHHH
EERKIDRLGSTSPISVDFRLLAATNRNLESSVNTGKFRSDLFYRINEFPIELPPLRSRRD
HHHHHHHCCCCCCCEEEEEEEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
DIPLLSKHFLEEITHKEKLPMLTISEEAKAALMRYDWPGNVRELRGLMRQMTWKTQGHTI
CCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCEE
ELHHLPAAFTEEGTIIGASGSLEEQLASAERAIIETALETAQGNRALTARMLGIHRTALY
EEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKMTRLGMEM
HHHHHHCCCC
>Mature Secondary Structure
MDTPATAAKTRKAEYCRCGVIFCDEAGRITAASKDYIWPAGMKAKAGEDLPAELLLLHAG
CCCCCCHHHHCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHEEEEECC
EWVFLEKDWFVQAEGKGRVEMLLFRRIRAADQVLGPYGDSAINEGMVHMVLNNPYEGLTS
CEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCHHHC
VDREGKVTFLSPVNEKWLGLEEGGGMGLPLSSFAPGSRLAEIALTGVSDTTQVVDIQGQT
CCCCCCEEEECCCCCHHCCEECCCCCCCCHHCCCCCCCEEEEEEECCCCCCEEEEECCCE
KVTVNLPIKKGQKVIGAVGRILFKSTDQIDKLANRIRTMELKVERYETLLDEMRGNRYNF
EEEEECCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DKILTNNKPMRALIDQARRVADSSATVLILGESGTGKELFAQALHEGSARRRGPFVAINC
HHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEC
SALPHDLIESELFGYDEGAFSGAKRKGKPGKFELACGGTLFLDEIGELPLESQAKLLRVL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEEHHHHCCCCCHHHHHHHHHH
EERKIDRLGSTSPISVDFRLLAATNRNLESSVNTGKFRSDLFYRINEFPIELPPLRSRRD
HHHHHHHCCCCCCCEEEEEEEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
DIPLLSKHFLEEITHKEKLPMLTISEEAKAALMRYDWPGNVRELRGLMRQMTWKTQGHTI
CCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCEE
ELHHLPAAFTEEGTIIGASGSLEEQLASAERAIIETALETAQGNRALTARMLGIHRTALY
EEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKMTRLGMEM
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA