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The map label for this gene is murB-2 [H]

Identifier: 197119550

GI number: 197119550

Start: 3668009

End: 3668992

Strand: Direct

Name: murB-2 [H]

Synonym: Gbem_3180

Alternate gene names: 197119550

Gene position: 3668009-3668992 (Clockwise)

Preceding gene: 197119549

Following gene: 197119564

Centisome position: 79.48

GC content: 65.96

Gene sequence:

>984_bases
ATGTATACCGACCAGAGAAAAGACAACCAGCCGTTAGAGCTTTCGCGGGACATCCCCCTCGCCCCCTTCACCTCGTTCAA
GATCGGTGGCCCGGCCAGGTTTTTGACCAAGGCCCGGACGCTGGAACAGCTGAAGCAGGCGCTTTCCTTCGCTAAGGCAG
AAGGGATTCCCTTCCTCATCGTCGGGGGTGGATCCAACCTGCTGGTGAGCGACCGCGGTTTCGACGGCATCGCGATCAGG
CTGCAGATGAAAGGGATCAAGGTCCAAGGGAACCGGGTCGAGGCGCAGGCGGGAGTCGACCTCATGGCGCTGGTGGAGCA
TGCGGCACACTGGGGGCTGGCGGGGATCGAGCGGCTGGCTGGCATTCCGGGGCTCTTCGGGGGGGCGGTGCGCGGCAATG
CGGGCGCCTACGGCAGTTGCATCGGCGACGTGATCGAGAGGGTCCACGCGCTGCGGGCGGACACCCTGGAACTGGTCACG
CTCGCGCGGGACGCCTGCCAGTTCCAGTACCGCAACAGCCGTTTTAAGAAGGACCACGGGCTGGTGGTGGTGGCGGCGAG
CCTGCTCCTTGAGCCGGGGGCCCCCCAGGAGATCCTGAGCCGGGCGGAGGCGACGGTGAGAAAACGGCAAGCCCGCCAGC
TGCAATGCGACCTGAGCGCAGGCTCGTTCTTCATGAATCCGGTGGTGCGCGACCCCGAGCTGATCCAAAGGTTCGAGACC
GAGCAGGGGACCCACTGCAGGGACGGCAGGATCCCGGCCGGATGGCTCATCGACAGGGCCAGGCTGCGCAGCCTTTCCGT
GGGAGCGGCCATGGTCAGCCCAAGGCACGCCAATTACCTGATCAACACCGGCAACGCCAGCGCCCAGGAGATGGTCAGGC
TCGCCGAACTGGTGAAGGACGAGGTGCGGGCGTCGCTGGGGGTGCAGCTGGAGGAGGAGGTGAGCTGCGTCGGCTTCATT
CCGGCTGGGCCGCTTCCCTCCTGA

Upstream 100 bases:

>100_bases
CTTGTCAACACCTCAGCTCTTATCGCCACCCGCCGGCGCTACTTGAGCTGAAAATGCCCCTTCGTTGGCTTGAGCGTAAA
CTGTTGCTATTATAGGGCCT

Downstream 100 bases:

>100_bases
ACTCGGCGAACGCCTCCTCGAGATCCTGGTAAAGCCCCGTCATCCCCTCAAGCTCTTCCTGCTGCGCTGTCTTTTTCTCC
ATCTCGAACGCAATTATCCG

Product: UDP-N-acetylenolpyruvylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MYTDQRKDNQPLELSRDIPLAPFTSFKIGGPARFLTKARTLEQLKQALSFAKAEGIPFLIVGGGSNLLVSDRGFDGIAIR
LQMKGIKVQGNRVEAQAGVDLMALVEHAAHWGLAGIERLAGIPGLFGGAVRGNAGAYGSCIGDVIERVHALRADTLELVT
LARDACQFQYRNSRFKKDHGLVVVAASLLLEPGAPQEILSRAEATVRKRQARQLQCDLSAGSFFMNPVVRDPELIQRFET
EQGTHCRDGRIPAGWLIDRARLRSLSVGAAMVSPRHANYLINTGNASAQEMVRLAELVKDEVRASLGVQLEEEVSCVGFI
PAGPLPS

Sequences:

>Translated_327_residues
MYTDQRKDNQPLELSRDIPLAPFTSFKIGGPARFLTKARTLEQLKQALSFAKAEGIPFLIVGGGSNLLVSDRGFDGIAIR
LQMKGIKVQGNRVEAQAGVDLMALVEHAAHWGLAGIERLAGIPGLFGGAVRGNAGAYGSCIGDVIERVHALRADTLELVT
LARDACQFQYRNSRFKKDHGLVVVAASLLLEPGAPQEILSRAEATVRKRQARQLQCDLSAGSFFMNPVVRDPELIQRFET
EQGTHCRDGRIPAGWLIDRARLRSLSVGAAMVSPRHANYLINTGNASAQEMVRLAELVKDEVRASLGVQLEEEVSCVGFI
PAGPLPS
>Mature_327_residues
MYTDQRKDNQPLELSRDIPLAPFTSFKIGGPARFLTKARTLEQLKQALSFAKAEGIPFLIVGGGSNLLVSDRGFDGIAIR
LQMKGIKVQGNRVEAQAGVDLMALVEHAAHWGLAGIERLAGIPGLFGGAVRGNAGAYGSCIGDVIERVHALRADTLELVT
LARDACQFQYRNSRFKKDHGLVVVAASLLLEPGAPQEILSRAEATVRKRQARQLQCDLSAGSFFMNPVVRDPELIQRFET
EQGTHCRDGRIPAGWLIDRARLRSLSVGAAMVSPRHANYLINTGNASAQEMVRLAELVKDEVRASLGVQLEEEVSCVGFI
PAGPLPS

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=328, Percent_Identity=32.9268292682927, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35431; Mature: 35431

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTDQRKDNQPLELSRDIPLAPFTSFKIGGPARFLTKARTLEQLKQALSFAKAEGIPFLI
CCCCCCCCCCCCEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VGGGSNLLVSDRGFDGIAIRLQMKGIKVQGNRVEAQAGVDLMALVEHAAHWGLAGIERLA
EECCCEEEEECCCCCCEEEEEEEECEEEECCEEEHHHCCHHHHHHHHHHHCCHHHHHHHC
GIPGLFGGAVRGNAGAYGSCIGDVIERVHALRADTLELVTLARDACQFQYRNSRFKKDHG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LVVVAASLLLEPGAPQEILSRAEATVRKRQARQLQCDLSAGSFFMNPVVRDPELIQRFET
EEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCHHHHHHHHC
EQGTHCRDGRIPAGWLIDRARLRSLSVGAAMVSPRHANYLINTGNASAQEMVRLAELVKD
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
EVRASLGVQLEEEVSCVGFIPAGPLPS
HHHHHHCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MYTDQRKDNQPLELSRDIPLAPFTSFKIGGPARFLTKARTLEQLKQALSFAKAEGIPFLI
CCCCCCCCCCCCEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VGGGSNLLVSDRGFDGIAIRLQMKGIKVQGNRVEAQAGVDLMALVEHAAHWGLAGIERLA
EECCCEEEEECCCCCCEEEEEEEECEEEECCEEEHHHCCHHHHHHHHHHHCCHHHHHHHC
GIPGLFGGAVRGNAGAYGSCIGDVIERVHALRADTLELVTLARDACQFQYRNSRFKKDHG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LVVVAASLLLEPGAPQEILSRAEATVRKRQARQLQCDLSAGSFFMNPVVRDPELIQRFET
EEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCHHHHHHHHC
EQGTHCRDGRIPAGWLIDRARLRSLSVGAAMVSPRHANYLINTGNASAQEMVRLAELVKD
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
EVRASLGVQLEEEVSCVGFIPAGPLPS
HHHHHHCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA