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The map label for this gene is mcp042 [C]

Identifier: 197117123

GI number: 197117123

Start: 859695

End: 861308

Strand: Direct

Name: mcp042 [C]

Synonym: Gbem_0728

Alternate gene names: 197117123

Gene position: 859695-861308 (Clockwise)

Preceding gene: 197117122

Following gene: 197117126

Centisome position: 18.63

GC content: 62.83

Gene sequence:

>1614_bases
ATGAAGATTGGAGTTCGCCTCGGAGCGTGTTTTGGGATCATCATAGTGATCATGTTTTCGGTCACGGCCTTTACCGGCAA
CAGGCTTTCCTACATCAACAGCAGGGTCAAGGTCATCGTAGAGGATAAGTATCCCAAGACCGTTCTTCTGAACCAGGTGA
ACGAGAACATCAACGTCATCGCCCGCACCTTGCGCAACGCCGTAATCGTCGAAGATCCGGTCCTTGCGAAAAAGGAGCTG
GAGCGCATTCCGGAGATCAGCAAGAGCACGGTGCAGTGCTTCGAAAAGCTGAAGAAGACGGCGACGAACCCTGCGGAACT
TGCCGCCTTCAAGGAAATCGATGCGGTGAGGGGACCGTACAAGGCTACCCAGAAGGAGCTGGTCGCGCTGATAGAGGCAA
ACTCCAAAGCAGAGGCGGGGGCGCTGCTCTTGGGAAGGTACCGGGATGTACAGAGGGAGTACATAGCGGCGGTGAAGAAG
ATGATCGACGTGCAGTCGAACCATCTGGTCGATCTCGGGCGCAACGTCGAGGATGCCTATAAGCTCGCCAGGAACCTCAG
CATACTGTTCTCCGCCATCGCCATGGTGCTCGGCGGGATCTTCGCCTACCTGGTCACCAGGAGCATCACGAAGCCGGTCG
AGAACCTGGTGTCGGTCAATGCGAGGCTGGCCGAAGGCGACCTGACCGCCGTCCCCGAACTGCACGGATGCGATGAACTT
GGCCTTCTTGCCGACTCCACCCGCAAGGTGGTGGCCAACATGCGCGAGGTTCTGGGGCAGGTGGCGCAAGCCTCGACCTC
GGTCGCCTCTGCCTCCCAGAGGCTGCAGCAGACGGCTTCGGCCATCGCCACCGGCGCCGAGGACATGGTGGGGCAGATCA
GTACAGTAGCGGTGGCGAGCGAAGAGATGGCCGCCACCAGCAACGATATCGCCTGCAACTGCGGCATGGCGGCGGAAAGT
TCCCAGGCTACCAGCAGCGCGGCCGTCAAGGGTAGCGGCGTCGTCGACGAGACCATACAGGGGATGGGAAGGATCGCCGA
GCAGGTAAAGGAGTCCTCGCGGACGGTGGAGAGCCTCGGGGTGCGCTCGGAGCAGATCGGCGAGATCGTGGGTACCATCG
AAGACATCGCCGACCAGACCAACCTCCTTGCCTTGAACGCCGCCATAGAGGCCGCCCGTGCGGGAGAGCAGGGTAGGGGG
TTCGCGGTCGTGGCAGACGAGGTGCGCGCGCTGGCGGAGCGGACCACCAGGGCGACCAGGGAGATCTCGGGGATGATCCA
GAACATCCAGGGCGAGACCAGGGCCGCCGTAAAGGCGATGGAAGAAGGCGTAGCCCAAGTGGTCAAGGGTGCGGCCAGCT
CCGAACAGTCGGGGGAGGCCCTGCAGGAGATCCTGCAGCAGGTGAACGAGCTCTCCATGCAGATCAACCAGGTGGCGACT
GCGGCGGCGGAGCAGACGGCGACCACCAACGAGATCACGGCCAACGTGCAGCGGGTGAGCGGCGTGATCCAGGACACGGC
ACGCGGCGCCGGCGATACTGCGGCAGCGGCGGCCCAACTCGCGGCCCACGCCGATCAGCTGCAGGGGCTGGTGCGCAGGT
TCCGGCTGGCCTAG

Upstream 100 bases:

>100_bases
ACATTTTTCCCCCTCAAGTAAACAACATGAATGACGATATGGACCGGACGGTAAGTAAGCTGTCGGGTGCCATCGAAGTG
GGATCAAAAGGAGATCGTGA

Downstream 100 bases:

>100_bases
CCATCATTTATGATTCAAGGGACCCATAGCAATCAGCGGGTCCTTTTCCAGGCGCAAAACGAGAGAGCCGCATCCATGAC
ACGGCTCTCTCGTTTTGCAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MKIGVRLGACFGIIIVIMFSVTAFTGNRLSYINSRVKVIVEDKYPKTVLLNQVNENINVIARTLRNAVIVEDPVLAKKEL
ERIPEISKSTVQCFEKLKKTATNPAELAAFKEIDAVRGPYKATQKELVALIEANSKAEAGALLLGRYRDVQREYIAAVKK
MIDVQSNHLVDLGRNVEDAYKLARNLSILFSAIAMVLGGIFAYLVTRSITKPVENLVSVNARLAEGDLTAVPELHGCDEL
GLLADSTRKVVANMREVLGQVAQASTSVASASQRLQQTASAIATGAEDMVGQISTVAVASEEMAATSNDIACNCGMAAES
SQATSSAAVKGSGVVDETIQGMGRIAEQVKESSRTVESLGVRSEQIGEIVGTIEDIADQTNLLALNAAIEAARAGEQGRG
FAVVADEVRALAERTTRATREISGMIQNIQGETRAAVKAMEEGVAQVVKGAASSEQSGEALQEILQQVNELSMQINQVAT
AAAEQTATTNEITANVQRVSGVIQDTARGAGDTAAAAAQLAAHADQLQGLVRRFRLA

Sequences:

>Translated_537_residues
MKIGVRLGACFGIIIVIMFSVTAFTGNRLSYINSRVKVIVEDKYPKTVLLNQVNENINVIARTLRNAVIVEDPVLAKKEL
ERIPEISKSTVQCFEKLKKTATNPAELAAFKEIDAVRGPYKATQKELVALIEANSKAEAGALLLGRYRDVQREYIAAVKK
MIDVQSNHLVDLGRNVEDAYKLARNLSILFSAIAMVLGGIFAYLVTRSITKPVENLVSVNARLAEGDLTAVPELHGCDEL
GLLADSTRKVVANMREVLGQVAQASTSVASASQRLQQTASAIATGAEDMVGQISTVAVASEEMAATSNDIACNCGMAAES
SQATSSAAVKGSGVVDETIQGMGRIAEQVKESSRTVESLGVRSEQIGEIVGTIEDIADQTNLLALNAAIEAARAGEQGRG
FAVVADEVRALAERTTRATREISGMIQNIQGETRAAVKAMEEGVAQVVKGAASSEQSGEALQEILQQVNELSMQINQVAT
AAAEQTATTNEITANVQRVSGVIQDTARGAGDTAAAAAQLAAHADQLQGLVRRFRLA
>Mature_537_residues
MKIGVRLGACFGIIIVIMFSVTAFTGNRLSYINSRVKVIVEDKYPKTVLLNQVNENINVIARTLRNAVIVEDPVLAKKEL
ERIPEISKSTVQCFEKLKKTATNPAELAAFKEIDAVRGPYKATQKELVALIEANSKAEAGALLLGRYRDVQREYIAAVKK
MIDVQSNHLVDLGRNVEDAYKLARNLSILFSAIAMVLGGIFAYLVTRSITKPVENLVSVNARLAEGDLTAVPELHGCDEL
GLLADSTRKVVANMREVLGQVAQASTSVASASQRLQQTASAIATGAEDMVGQISTVAVASEEMAATSNDIACNCGMAAES
SQATSSAAVKGSGVVDETIQGMGRIAEQVKESSRTVESLGVRSEQIGEIVGTIEDIADQTNLLALNAAIEAARAGEQGRG
FAVVADEVRALAERTTRATREISGMIQNIQGETRAAVKAMEEGVAQVVKGAASSEQSGEALQEILQQVNELSMQINQVAT
AAAEQTATTNEITANVQRVSGVIQDTARGAGDTAAAAAQLAAHADQLQGLVRRFRLA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=400, Percent_Identity=31.25, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788195, Length=444, Percent_Identity=27.7027027027027, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=389, Percent_Identity=27.7634961439589, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789453, Length=344, Percent_Identity=28.4883720930233, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1788194, Length=334, Percent_Identity=29.940119760479, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56950; Mature: 56950

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVRLGACFGIIIVIMFSVTAFTGNRLSYINSRVKVIVEDKYPKTVLLNQVNENINVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEECCCCCHHHHHHHCCHHHHH
ARTLRNAVIVEDPVLAKKELERIPEISKSTVQCFEKLKKTATNPAELAAFKEIDAVRGPY
HHHHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
KATQKELVALIEANSKAEAGALLLGRYRDVQREYIAAVKKMIDVQSNHLVDLGRNVEDAY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
KLARNLSILFSAIAMVLGGIFAYLVTRSITKPVENLVSVNARLAEGDLTAVPELHGCDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCHH
GLLADSTRKVVANMREVLGQVAQASTSVASASQRLQQTASAIATGAEDMVGQISTVAVAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEMAATSNDIACNCGMAAESSQATSSAAVKGSGVVDETIQGMGRIAEQVKESSRTVESLG
HHHHCCCCCCEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VRSEQIGEIVGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTTRATR
CCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
EISGMIQNIQGETRAAVKAMEEGVAQVVKGAASSEQSGEALQEILQQVNELSMQINQVAT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAEQTATTNEITANVQRVSGVIQDTARGAGDTAAAAAQLAAHADQLQGLVRRFRLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGVRLGACFGIIIVIMFSVTAFTGNRLSYINSRVKVIVEDKYPKTVLLNQVNENINVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEECCCCCHHHHHHHCCHHHHH
ARTLRNAVIVEDPVLAKKELERIPEISKSTVQCFEKLKKTATNPAELAAFKEIDAVRGPY
HHHHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
KATQKELVALIEANSKAEAGALLLGRYRDVQREYIAAVKKMIDVQSNHLVDLGRNVEDAY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
KLARNLSILFSAIAMVLGGIFAYLVTRSITKPVENLVSVNARLAEGDLTAVPELHGCDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCHH
GLLADSTRKVVANMREVLGQVAQASTSVASASQRLQQTASAIATGAEDMVGQISTVAVAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEMAATSNDIACNCGMAAESSQATSSAAVKGSGVVDETIQGMGRIAEQVKESSRTVESLG
HHHHCCCCCCEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
VRSEQIGEIVGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTTRATR
CCHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHH
EISGMIQNIQGETRAAVKAMEEGVAQVVKGAASSEQSGEALQEILQQVNELSMQINQVAT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAAEQTATTNEITANVQRVSGVIQDTARGAGDTAAAAAQLAAHADQLQGLVRRFRLA
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA