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The map label for this gene is cheA-3 [H]

Identifier: 197117019

GI number: 197117019

Start: 742520

End: 744151

Strand: Reverse

Name: cheA-3 [H]

Synonym: Gbem_0622

Alternate gene names: 197117019

Gene position: 744151-742520 (Counterclockwise)

Preceding gene: 197117020

Following gene: 197117018

Centisome position: 16.12

GC content: 66.42

Gene sequence:

>1632_bases
ATGGACATGTCGCAGTACAAAAGCCTCTTCCTCTCCGAGAGCAGGGAGTACCTGAAGACCATCTCCGACCAGGTGGTCGC
CTTGGAGCAGGCTCCTGCCGAGAGAAGCGCCGTCGACGCCCTCTTCAGGGGAGCCCATTCGCTCAAGGGGATGGCCGCCT
CTATGGAGTACGGCGACGTCGTGGTGGTGGCGCACAGCATGGAAGACCTGATGGCGCGGGTCCGGGACGGTGCCCTTTGC
TTCGAGGCCGGGGTGGCCGATCTGCTCCTGGAGGGTGTGGACCTGATCGACGTCATGCTGGCCGACGTGGAGGCGGACCG
GGAATGCACCCGCCCTCCCGACGACTTCGCGGAGAGGCTCCGGGGTTACACGCCGGCTCTCCCGAAAAAGCAAGCGCCCG
CGGGGGAGCCCCCGGCGGAGCACCCAGCGCCCCAGGCGGCGCAGCCGGGAGGCGAACCCGAGAAGGCCAAGGAGCCGGCC
GGCGAGGCGAGCGGCACGGTGCGGGTGAAGACGGAGCTTCTGGATCACCTGATCAACCTGACCGGCGAGCTGGTCACCAA
CAAGCACCGGCTGTTGAACGTGGCGCAGGAGGTGGCAAGCCCCGCCTTGAACGACGCGGTCTCCGAGACCGGGAAGCTTC
TGCGCGCCCTGCACGACGAGGTCATGAAGGTGCGCCTGATGCCCTTCGAGGCGATCTGCGACCGCTTCCAGCGCTCGGTC
CGAAGCCTCGCCAAGAAAAGCGGCAAGGAAATCAACTTCGAGCTGTCCGGCCGCGAGATCGGCATGGACCGCGGCATGCT
GGAGCAGTTGGTCGATCCGCTGAACCACATCCTGAGAAACGCCGTGGACCACGGCATGGAGGAAAGCGCAGAGCGGGCGG
CGCAGGGCAAGCCCCCCCGCGGGACGGTGAAGCTCTCCGTTTCCCGCGACCGTGACCGCATATCGATCCAGGTAAGCGAC
GACGGCCGGGGGATGGAACCGCAGAAGATGATTGAAGCGGCCGTCGCCAAGGGGGTGATCACCCCGGAAGAAGGGGCGCT
CCTGTCGCCGCGCCAGGCGCTGATGCTCTCCTGCATCCCGGGCTTCTCGACCGCCAAGGTCGTCACCGACATCTCGGGGC
GCGGCGTCGGCATGGACGCGGTGAACGCGGCCATCCAGAAGCTTGGGGGAACCCTGGTGATAGAGAGCGAGCCCGGACAG
GGAAGCACCTTCACGCTCAGGCTCCCCATGACCATCGCCATCATCCACGCGCTGGTGGTGCAGTGCGGCAACGTGAAAGG
GGCGGTCCCGGTGACGGGGGTGCTGCGCACCGTCGAGCTGGCGCGCCACCAGATCGAAACCATGGGAAAGCGGCAGATGT
TCCAGCTGGACGGCGAGGCCATCCCGCTTTTGAGCCTGAACCGGATACTGGGCCTGCCGCTGGGGCGTTTCCCCAACGGG
ATCCTGCCGCTCTTCGTCACCGAGGCGAAGGGGAGGCGGGTCGGCATCGTGGTGGACCGCTTTCTAGGGCAGCACGAACT
CTTCGTAAAACCTTTCGGCAGGCCTTTATGCAAGATGGCCGGACTCGCCGGCGGGGCGACGCTCGGGGACGGAGAAATCG
TCACCATCCTCGACCTGGCCGGCCTGTTGTGA

Upstream 100 bases:

>100_bases
CGAGGCGGCCGCGAAGGCGGGGGCCAAGGCTTTCATCCTGAAGCCGTTCAATCCGGAGCTTGTGGCGCGCACCCTTAGGG
AAGTGGCCGAGGGATAGCGG

Downstream 100 bases:

>100_bases
GTTAAGCGGCAAAACAGTTTCCCGGGCTTTTACCGGGGCAACGTCTAACGGAGGCTTACATGCCCAATCCCGTCCTGCAA
CAGGCCGACCTGGCCGCACT

Product: chemotaxis sensor histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MDMSQYKSLFLSESREYLKTISDQVVALEQAPAERSAVDALFRGAHSLKGMAASMEYGDVVVVAHSMEDLMARVRDGALC
FEAGVADLLLEGVDLIDVMLADVEADRECTRPPDDFAERLRGYTPALPKKQAPAGEPPAEHPAPQAAQPGGEPEKAKEPA
GEASGTVRVKTELLDHLINLTGELVTNKHRLLNVAQEVASPALNDAVSETGKLLRALHDEVMKVRLMPFEAICDRFQRSV
RSLAKKSGKEINFELSGREIGMDRGMLEQLVDPLNHILRNAVDHGMEESAERAAQGKPPRGTVKLSVSRDRDRISIQVSD
DGRGMEPQKMIEAAVAKGVITPEEGALLSPRQALMLSCIPGFSTAKVVTDISGRGVGMDAVNAAIQKLGGTLVIESEPGQ
GSTFTLRLPMTIAIIHALVVQCGNVKGAVPVTGVLRTVELARHQIETMGKRQMFQLDGEAIPLLSLNRILGLPLGRFPNG
ILPLFVTEAKGRRVGIVVDRFLGQHELFVKPFGRPLCKMAGLAGGATLGDGEIVTILDLAGLL

Sequences:

>Translated_543_residues
MDMSQYKSLFLSESREYLKTISDQVVALEQAPAERSAVDALFRGAHSLKGMAASMEYGDVVVVAHSMEDLMARVRDGALC
FEAGVADLLLEGVDLIDVMLADVEADRECTRPPDDFAERLRGYTPALPKKQAPAGEPPAEHPAPQAAQPGGEPEKAKEPA
GEASGTVRVKTELLDHLINLTGELVTNKHRLLNVAQEVASPALNDAVSETGKLLRALHDEVMKVRLMPFEAICDRFQRSV
RSLAKKSGKEINFELSGREIGMDRGMLEQLVDPLNHILRNAVDHGMEESAERAAQGKPPRGTVKLSVSRDRDRISIQVSD
DGRGMEPQKMIEAAVAKGVITPEEGALLSPRQALMLSCIPGFSTAKVVTDISGRGVGMDAVNAAIQKLGGTLVIESEPGQ
GSTFTLRLPMTIAIIHALVVQCGNVKGAVPVTGVLRTVELARHQIETMGKRQMFQLDGEAIPLLSLNRILGLPLGRFPNG
ILPLFVTEAKGRRVGIVVDRFLGQHELFVKPFGRPLCKMAGLAGGATLGDGEIVTILDLAGLL
>Mature_543_residues
MDMSQYKSLFLSESREYLKTISDQVVALEQAPAERSAVDALFRGAHSLKGMAASMEYGDVVVVAHSMEDLMARVRDGALC
FEAGVADLLLEGVDLIDVMLADVEADRECTRPPDDFAERLRGYTPALPKKQAPAGEPPAEHPAPQAAQPGGEPEKAKEPA
GEASGTVRVKTELLDHLINLTGELVTNKHRLLNVAQEVASPALNDAVSETGKLLRALHDEVMKVRLMPFEAICDRFQRSV
RSLAKKSGKEINFELSGREIGMDRGMLEQLVDPLNHILRNAVDHGMEESAERAAQGKPPRGTVKLSVSRDRDRISIQVSD
DGRGMEPQKMIEAAVAKGVITPEEGALLSPRQALMLSCIPGFSTAKVVTDISGRGVGMDAVNAAIQKLGGTLVIESEPGQ
GSTFTLRLPMTIAIIHALVVQCGNVKGAVPVTGVLRTVELARHQIETMGKRQMFQLDGEAIPLLSLNRILGLPLGRFPNG
ILPLFVTEAKGRRVGIVVDRFLGQHELFVKPFGRPLCKMAGLAGGATLGDGEIVTILDLAGLL

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=410, Percent_Identity=33.4146341463415, Blast_Score=244, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58388; Mature: 58388

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMSQYKSLFLSESREYLKTISDQVVALEQAPAERSAVDALFRGAHSLKGMAASMEYGDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVAHSMEDLMARVRDGALCFEAGVADLLLEGVDLIDVMLADVEADRECTRPPDDFAERL
EEEECCHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RGYTPALPKKQAPAGEPPAEHPAPQAAQPGGEPEKAKEPAGEASGTVRVKTELLDHLINL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHH
TGELVTNKHRLLNVAQEVASPALNDAVSETGKLLRALHDEVMKVRLMPFEAICDRFQRSV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RSLAKKSGKEINFELSGREIGMDRGMLEQLVDPLNHILRNAVDHGMEESAERAAQGKPPR
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
GTVKLSVSRDRDRISIQVSDDGRGMEPQKMIEAAVAKGVITPEEGALLSPRQALMLSCIP
CEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
GFSTAKVVTDISGRGVGMDAVNAAIQKLGGTLVIESEPGQGSTFTLRLPMTIAIIHALVV
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEEEECHHHHHHHHHHHH
QCGNVKGAVPVTGVLRTVELARHQIETMGKRQMFQLDGEAIPLLSLNRILGLPLGRFPNG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCCCC
ILPLFVTEAKGRRVGIVVDRFLGQHELFVKPFGRPLCKMAGLAGGATLGDGEIVTILDLA
CEEEEEECCCCCEEEEEHHHHCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCEEEHHHHH
GLL
CCC
>Mature Secondary Structure
MDMSQYKSLFLSESREYLKTISDQVVALEQAPAERSAVDALFRGAHSLKGMAASMEYGDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVVAHSMEDLMARVRDGALCFEAGVADLLLEGVDLIDVMLADVEADRECTRPPDDFAERL
EEEECCHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RGYTPALPKKQAPAGEPPAEHPAPQAAQPGGEPEKAKEPAGEASGTVRVKTELLDHLINL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHH
TGELVTNKHRLLNVAQEVASPALNDAVSETGKLLRALHDEVMKVRLMPFEAICDRFQRSV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RSLAKKSGKEINFELSGREIGMDRGMLEQLVDPLNHILRNAVDHGMEESAERAAQGKPPR
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
GTVKLSVSRDRDRISIQVSDDGRGMEPQKMIEAAVAKGVITPEEGALLSPRQALMLSCIP
CEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCC
GFSTAKVVTDISGRGVGMDAVNAAIQKLGGTLVIESEPGQGSTFTLRLPMTIAIIHALVV
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEEEEECHHHHHHHHHHHH
QCGNVKGAVPVTGVLRTVELARHQIETMGKRQMFQLDGEAIPLLSLNRILGLPLGRFPNG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCCCC
ILPLFVTEAKGRRVGIVVDRFLGQHELFVKPFGRPLCKMAGLAGGATLGDGEIVTILDLA
CEEEEEECCCCCEEEEEHHHHCCCCCEEECCCCCHHHHHHCCCCCCCCCCCCEEEHHHHH
GLL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]