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The map label for this gene is pbpA [H]

Identifier: 197116977

GI number: 197116977

Start: 700473

End: 701810

Strand: Reverse

Name: pbpA [H]

Synonym: Gbem_0580

Alternate gene names: 197116977

Gene position: 701810-700473 (Counterclockwise)

Preceding gene: 197116978

Following gene: 197116976

Centisome position: 15.21

GC content: 64.13

Gene sequence:

>1338_bases
ATGCAAGATTTCAAAGACATAGACAAACAAAACCGAAGCAAGAGATCAATCAGGGCCAAGAGACTTGAAGGGCGCAACGC
CTTCAAGACGATCCAGGAGGATGACGAGAAGCCGCGCAAGACGCGGTACGGCATCGTCTTGGGGGTCATCGCGGCACTGC
TAGCCTCCTACCCGATCATCTCCGTGTTGAATTCCTCACCCGCAAAAACGGCCATGCCGACAGCTGCGGCGGAAACGGTC
TCCTTGAAGAATCTGGACCAGGGGAGCGCCTTCCGCCTGGCGGCGGAGGCCTACCCGAAGGCGCAGCCGCAAGGGGGATC
CCTCGTGGCCCCCCTGCCGCAGGGGGGGCAGGTGGTGTACGCCATCAACGAGGACGTGCAGAAGCGGGTCGAAAAGGTGC
TGTCCGACTACAAGGTCCCTTATGGGCTGTTCGTCGCCATGGAACCGAGAACCGGGCGCATCCTCGCCATGGTCTCCCAT
TCCTCGGTCGAGCCTGCGTGGGAAAAGGACGGTAGCTACCACCTCTACCCGCTCGCCTCGCTCTTCAAGATCGTCACCGC
GACCGCCGCGCTGGAAAGCAAGAAGGTGACCCCGGAAACCCCCTTTGCCTTCAACGGCCGCCTCACCTCGGAAAGCCCCA
AGTACTGGCGGGTGCACCCCGGGCGCGGCAACCAGCAGATGCCGCTTGCGGTCGCCATGGGTAAATCGGTGAATCCCGTG
TACGGCAGGCTGGCCGGAGAGGTGGTGGGACGAGACCCGCTCTTGTTGTACGCCGGACGCTACGGCTTCAACCAGGCGCT
GCTCCCAGGCGCCCCGATAATGTCGAGCACCGCCCCCGCGCCTTCCACCGACAACGAGCTGATGCGGATGGGAGCGGGAC
TGAACCGCGAAGTGAAGGCGTCTCCCTTCCATGCAGCCGCCATGATGGCCGCGGTCGCCAACGGCGGCGTCATGATGGCC
CCGGGCTTCGCCAAGGAGATACGCGACGCCAAGGGGAACCTGGTGTTTACGCACAAGCCGCAGGCGCTGAGGACCGTGAT
GACGCCGGAGACGGCTGCGTCGATGGCGCGCATGCTCTCCACCACGGTGCAAACCGGCACCTCGCGCCGGGCCTTCCACG
ACAGGAGGGGTAGGCGGATGCTCGCCTCGGTCAGCATCGCGGCCAAGACCGGATCCATCGACGGGACCGATCCCGCCGGC
CATTACAGCTGGTTTGCAGCCTATGCGCCGATGGAGGACCCGCAGATAGCGCTCGCGGCGCTAGTGGTGAACGGGAACAA
GTGGCGCATAAAGGCGACCTCGGTCGGCGAGCAAGCGCTGGAGGCGTTCTTCAGGTAG

Upstream 100 bases:

>100_bases
GATGGATCTGGCGGCTCCAGAAAAGAGTCCGGCCGGCGTTGACAAAGAGGGAGCAGTTGACATATAGTGGCCCGATTAAA
CTCCAGACGTGAAGCGGGTT

Downstream 100 bases:

>100_bases
GGGACGGCAATGGAATGTTCAGGATGCGGCACCTGCTGCGTTGCGCCGGACATCAGCACGCTGGGGAAAAAGGCGGGGGA
GAGATGCCCGCACCTCATGG

Product: transpeptidase

Products: NA

Alternate protein names: PBPA [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQDFKDIDKQNRSKRSIRAKRLEGRNAFKTIQEDDEKPRKTRYGIVLGVIAALLASYPIISVLNSSPAKTAMPTAAAETV
SLKNLDQGSAFRLAAEAYPKAQPQGGSLVAPLPQGGQVVYAINEDVQKRVEKVLSDYKVPYGLFVAMEPRTGRILAMVSH
SSVEPAWEKDGSYHLYPLASLFKIVTATAALESKKVTPETPFAFNGRLTSESPKYWRVHPGRGNQQMPLAVAMGKSVNPV
YGRLAGEVVGRDPLLLYAGRYGFNQALLPGAPIMSSTAPAPSTDNELMRMGAGLNREVKASPFHAAAMMAAVANGGVMMA
PGFAKEIRDAKGNLVFTHKPQALRTVMTPETAASMARMLSTTVQTGTSRRAFHDRRGRRMLASVSIAAKTGSIDGTDPAG
HYSWFAAYAPMEDPQIALAALVVNGNKWRIKATSVGEQALEAFFR

Sequences:

>Translated_445_residues
MQDFKDIDKQNRSKRSIRAKRLEGRNAFKTIQEDDEKPRKTRYGIVLGVIAALLASYPIISVLNSSPAKTAMPTAAAETV
SLKNLDQGSAFRLAAEAYPKAQPQGGSLVAPLPQGGQVVYAINEDVQKRVEKVLSDYKVPYGLFVAMEPRTGRILAMVSH
SSVEPAWEKDGSYHLYPLASLFKIVTATAALESKKVTPETPFAFNGRLTSESPKYWRVHPGRGNQQMPLAVAMGKSVNPV
YGRLAGEVVGRDPLLLYAGRYGFNQALLPGAPIMSSTAPAPSTDNELMRMGAGLNREVKASPFHAAAMMAAVANGGVMMA
PGFAKEIRDAKGNLVFTHKPQALRTVMTPETAASMARMLSTTVQTGTSRRAFHDRRGRRMLASVSIAAKTGSIDGTDPAG
HYSWFAAYAPMEDPQIALAALVVNGNKWRIKATSVGEQALEAFFR
>Mature_445_residues
MQDFKDIDKQNRSKRSIRAKRLEGRNAFKTIQEDDEKPRKTRYGIVLGVIAALLASYPIISVLNSSPAKTAMPTAAAETV
SLKNLDQGSAFRLAAEAYPKAQPQGGSLVAPLPQGGQVVYAINEDVQKRVEKVLSDYKVPYGLFVAMEPRTGRILAMVSH
SSVEPAWEKDGSYHLYPLASLFKIVTATAALESKKVTPETPFAFNGRLTSESPKYWRVHPGRGNQQMPLAVAMGKSVNPV
YGRLAGEVVGRDPLLLYAGRYGFNQALLPGAPIMSSTAPAPSTDNELMRMGAGLNREVKASPFHAAAMMAAVANGGVMMA
PGFAKEIRDAKGNLVFTHKPQALRTVMTPETAASMARMLSTTVQTGTSRRAFHDRRGRRMLASVSIAAKTGSIDGTDPAG
HYSWFAAYAPMEDPQIALAALVVNGNKWRIKATSVGEQALEAFFR

Specific function: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Probable). Note=Localized to the division site (septum) along with newly synthesized peptidoglycan, between segregated nucleoids (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 48126; Mature: 48126

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFKDIDKQNRSKRSIRAKRLEGRNAFKTIQEDDEKPRKTRYGIVLGVIAALLASYPII
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
SVLNSSPAKTAMPTAAAETVSLKNLDQGSAFRLAAEAYPKAQPQGGSLVAPLPQGGQVVY
HHHCCCCCCCCCCCHHHHHEECCCCCCCCCEEEEHHHCCCCCCCCCCEEEECCCCCEEEE
AINEDVQKRVEKVLSDYKVPYGLFVAMEPRTGRILAMVSHSSVEPAWEKDGSYHLYPLAS
EECHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHCCCCEEEEHHHH
LFKIVTATAALESKKVTPETPFAFNGRLTSESPKYWRVHPGRGNQQMPLAVAMGKSVNPV
HHHHHHHHHHHHCCCCCCCCCCEECCEECCCCCCEEEEECCCCCCCCCEEEECCCCCCHH
YGRLAGEVVGRDPLLLYAGRYGFNQALLPGAPIMSSTAPAPSTDNELMRMGAGLNREVKA
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
SPFHAAAMMAAVANGGVMMAPGFAKEIRDAKGNLVFTHKPQALRTVMTPETAASMARMLS
CCHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHHHHHHHH
TTVQTGTSRRAFHDRRGRRMLASVSIAAKTGSIDGTDPAGHYSWFAAYAPMEDPQIALAA
HHHHCCCCHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEE
LVVNGNKWRIKATSVGEQALEAFFR
EEEECCEEEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MQDFKDIDKQNRSKRSIRAKRLEGRNAFKTIQEDDEKPRKTRYGIVLGVIAALLASYPII
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
SVLNSSPAKTAMPTAAAETVSLKNLDQGSAFRLAAEAYPKAQPQGGSLVAPLPQGGQVVY
HHHCCCCCCCCCCCHHHHHEECCCCCCCCCEEEEHHHCCCCCCCCCCEEEECCCCCEEEE
AINEDVQKRVEKVLSDYKVPYGLFVAMEPRTGRILAMVSHSSVEPAWEKDGSYHLYPLAS
EECHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHCCCCEEEEHHHH
LFKIVTATAALESKKVTPETPFAFNGRLTSESPKYWRVHPGRGNQQMPLAVAMGKSVNPV
HHHHHHHHHHHHCCCCCCCCCCEECCEECCCCCCEEEEECCCCCCCCCEEEECCCCCCHH
YGRLAGEVVGRDPLLLYAGRYGFNQALLPGAPIMSSTAPAPSTDNELMRMGAGLNREVKA
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
SPFHAAAMMAAVANGGVMMAPGFAKEIRDAKGNLVFTHKPQALRTVMTPETAASMARMLS
CCHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHHHHHHHH
TTVQTGTSRRAFHDRRGRRMLASVSIAAKTGSIDGTDPAGHYSWFAAYAPMEDPQIALAA
HHHHCCCCHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEE
LVVNGNKWRIKATSVGEQALEAFFR
EEEECCEEEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA