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The map label for this gene is accD5 [H]

Identifier: 197116959

GI number: 197116959

Start: 677732

End: 679456

Strand: Reverse

Name: accD5 [H]

Synonym: Gbem_0562

Alternate gene names: 197116959

Gene position: 679456-677732 (Counterclockwise)

Preceding gene: 197116960

Following gene: 197116958

Centisome position: 14.72

GC content: 63.13

Gene sequence:

>1725_bases
ATGTCTAATACCTTTATTCAGCCCTCATTGAAAAATCCGTTCGACGCCGGCGAGAAGGTCGAGTTCAACATCCCGGGCGA
GATCTCCCGCGCCACTGGCGGCTATGAAGAGGCCATGCAGGCAGGTTACGACCTGATCCAGCGCCCGATCAAGTCGGTGA
GCATCGACCAGATCGAGAAACAGCATTTCAAGAAACGCATGACCGTGTGGGAAAGGATTCGCGTCCTGACCGAGGCGGAG
CCCAACATCCTGTTCCAGAACTGGGGCAAGAACCTGGACGGCGCCTCGCTGGTAACCGGCATCCTCAACATCCACGGCCG
CGACGTCGCCGTGTACGGCCACGACTTCACGGTCCGCGCCGGTTCCATGGACGCCACCAACGGCAACAAGCTGGCCCGCC
TCTTCTACATGGCAGGCGAGAAGGGGATCCCGGTCATCGGCATGAACGACTCCGCCGGCGCCTACGTCCCGGCCGGCGTG
GGCGGCCTCGACGGTTACGCTGAGGCGTTCACGGCGCTGAGAAAGATCAGCGGCGTGGTCCCCTCCATCATGTGCATGTT
CGGCTTCAACGCGGGGGGCGGCTCCTACCTGCCGCGCCAGGGAAGCTTCGTGATCCAGCCGAAAGACACCTTCTTCGGCC
TCACCGGCCCGGGCGTTGTCAAGAGCGTCCTCGGCGAGGACGTGACCCCGGAGGATCTGGGCGGACCGAAGGTGCACGGC
CAGTCCGGCGTTGCCGACCTCACCGTCGAGGACGAAGTCGGGGCGCTCAGGACCGCGCTGCAGCTTCTCAACTACATCCC
CGACAACAACTCGGTGATGGCGCGCCACCAGGAGACGAGCGACCCGCTGGACAGGAAGACCTGGGAGATCAACACGCTGC
TCAAGAAGGCGTTCAACTCCCCGACCGGCTTCAACACCCCGTTCGACGTTTCCATCATCATCCAGCAGATCTGCGACCAC
GGCGATTATTTCGAAATGCAGCGCGACCGCGCCCGCAACGTCGTCACCGCCTTCGGCCGCCTGGGTGGCAACGTGATCGG
CTTCGTCGCCAACAACTCGGCCGTCGACTCCGGCCAGATCGACTGCGACGCCGCCTACAAGATCGCGCGCTTCAACCGCT
TCTGCAACATCTACAACATCCCGATCATCTTCATGGAAGACACCACCGGCTTCCTCCCCGGTCGCGAGCAGGAAGCCCGC
GGTATCGTCCAGGCCGGCCGCGCCATGCTCGACTCCATCGTCGACATCAGGACTCCGCGCATCCTCTTGATCCTGAGAAA
CGCCTACGGCGGCGCCTACGCCTCCTACAACAACTACCCGACCGGGGCCGACCTGGTCCTGGCGCTCCCCACCACCAGGC
TCGCCGTCATGGGTCCGGCCGGTAAGGAATTCGTCTACAAGGACGAGCTCAGGAAGATCAGGAACGCGGTCATCGAGCGC
GTCAAGCGCGGCACCCAGGAGCGGGTGGAGGCCGGCGTGAAGCCGGATCTCGCGAAACTCGACGCCGAGAAGGAAGCCGC
CGACTGGCTCAGGGCCGAGGAGGCGCTCCTCAACACCCGTTACGAGAAGGAACTGATGAACCCGAAAGAGGCCCTCTCGC
TCGGCTCCATCTCCTCTCTTGTCATGCCGACCGATCTCAGGAAAGTGCTCGGGGAGAACATGAACTTCTTCCTGCGCCAC
TACAAGCCGGGCCCCATGCAGTCCGTGCAGAGGGAGTTCCACTAA

Upstream 100 bases:

>100_bases
TACAACGCTTTTTTAATATCAATCAACAGGAGGACGTCGATGAGTTCCGCAGTGACCCCGCAGGAGATGCAAAATCCCAA
CGACCAGAAGGATGCCCGCA

Downstream 100 bases:

>100_bases
TGGCGACTACAGACATGGGACTGGGAACAACGGAAGCAGGGGGCATCGCTCCCGAGTTGCTGGCAGGATTGGGCGGGGCG
AAAGCCGAGCCCTGCTGCGG

Product: biotin-dependent acyl-CoA carboxyltransferase subunit

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSNTFIQPSLKNPFDAGEKVEFNIPGEISRATGGYEEAMQAGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIRVLTEAE
PNILFQNWGKNLDGASLVTGILNIHGRDVAVYGHDFTVRAGSMDATNGNKLARLFYMAGEKGIPVIGMNDSAGAYVPAGV
GGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPKDTFFGLTGPGVVKSVLGEDVTPEDLGGPKVHG
QSGVADLTVEDEVGALRTALQLLNYIPDNNSVMARHQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDH
GDYFEMQRDRARNVVTAFGRLGGNVIGFVANNSAVDSGQIDCDAAYKIARFNRFCNIYNIPIIFMEDTTGFLPGREQEAR
GIVQAGRAMLDSIVDIRTPRILLILRNAYGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRNAVIER
VKRGTQERVEAGVKPDLAKLDAEKEAADWLRAEEALLNTRYEKELMNPKEALSLGSISSLVMPTDLRKVLGENMNFFLRH
YKPGPMQSVQREFH

Sequences:

>Translated_574_residues
MSNTFIQPSLKNPFDAGEKVEFNIPGEISRATGGYEEAMQAGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIRVLTEAE
PNILFQNWGKNLDGASLVTGILNIHGRDVAVYGHDFTVRAGSMDATNGNKLARLFYMAGEKGIPVIGMNDSAGAYVPAGV
GGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPKDTFFGLTGPGVVKSVLGEDVTPEDLGGPKVHG
QSGVADLTVEDEVGALRTALQLLNYIPDNNSVMARHQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDH
GDYFEMQRDRARNVVTAFGRLGGNVIGFVANNSAVDSGQIDCDAAYKIARFNRFCNIYNIPIIFMEDTTGFLPGREQEAR
GIVQAGRAMLDSIVDIRTPRILLILRNAYGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRNAVIER
VKRGTQERVEAGVKPDLAKLDAEKEAADWLRAEEALLNTRYEKELMNPKEALSLGSISSLVMPTDLRKVLGENMNFFLRH
YKPGPMQSVQREFH
>Mature_573_residues
SNTFIQPSLKNPFDAGEKVEFNIPGEISRATGGYEEAMQAGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIRVLTEAEP
NILFQNWGKNLDGASLVTGILNIHGRDVAVYGHDFTVRAGSMDATNGNKLARLFYMAGEKGIPVIGMNDSAGAYVPAGVG
GLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPKDTFFGLTGPGVVKSVLGEDVTPEDLGGPKVHGQ
SGVADLTVEDEVGALRTALQLLNYIPDNNSVMARHQETSDPLDRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHG
DYFEMQRDRARNVVTAFGRLGGNVIGFVANNSAVDSGQIDCDAAYKIARFNRFCNIYNIPIIFMEDTTGFLPGREQEARG
IVQAGRAMLDSIVDIRTPRILLILRNAYGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRNAVIERV
KRGTQERVEAGVKPDLAKLDAEKEAADWLRAEEALLNTRYEKELMNPKEALSLGSISSLVMPTDLRKVLGENMNFFLRHY
KPGPMQSVQREFH

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=427, Percent_Identity=37.2365339578454, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI295821216, Length=447, Percent_Identity=35.5704697986577, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI11545863, Length=369, Percent_Identity=28.7262872628726, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI134142062, Length=416, Percent_Identity=26.4423076923077, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679960, Length=365, Percent_Identity=24.1095890410959, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679974, Length=365, Percent_Identity=24.1095890410959, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679977, Length=365, Percent_Identity=24.1095890410959, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679967, Length=365, Percent_Identity=24.1095890410959, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679971, Length=365, Percent_Identity=24.1095890410959, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=545, Percent_Identity=32.1100917431193, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI25147359, Length=545, Percent_Identity=32.1100917431193, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17552936, Length=524, Percent_Identity=25.5725190839695, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71997163, Length=295, Percent_Identity=23.0508474576271, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323863, Length=318, Percent_Identity=23.5849056603774, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324343, Length=318, Percent_Identity=23.8993710691824, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24586065, Length=466, Percent_Identity=26.3948497854077, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 63193; Mature: 63062

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTFIQPSLKNPFDAGEKVEFNIPGEISRATGGYEEAMQAGYDLIQRPIKSVSIDQIEK
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHFKKRMTVWERIRVLTEAEPNILFQNWGKNLDGASLVTGILNIHGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSMDATNGNKLARLFYMAGEKGIPVIGMNDSAGAYVPAGVGGLDGYAEAFTALRKISGVV
CCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPKDTFFGLTGPGVVKSVLGEDVTPEDLGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCC
QSGVADLTVEDEVGALRTALQLLNYIPDNNSVMARHQETSDPLDRKTWEINTLLKKAFNS
CCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
PTGFNTPFDVSIIIQQICDHGDYFEMQRDRARNVVTAFGRLGGNVIGFVANNSAVDSGQI
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
DCDAAYKIARFNRFCNIYNIPIIFMEDTTGFLPGREQEARGIVQAGRAMLDSIVDIRTPR
CHHHHHHHHHHHHHCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
ILLILRNAYGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRNAVIER
EEEEEECCCCCEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VKRGTQERVEAGVKPDLAKLDAEKEAADWLRAEEALLNTRYEKELMNPKEALSLGSISSL
HHCCCHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHH
VMPTDLRKVLGENMNFFLRHYKPGPMQSVQREFH
HCCHHHHHHHCCCCEEEHEECCCCCHHHHHHHCC
>Mature Secondary Structure 
SNTFIQPSLKNPFDAGEKVEFNIPGEISRATGGYEEAMQAGYDLIQRPIKSVSIDQIEK
CCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
QHFKKRMTVWERIRVLTEAEPNILFQNWGKNLDGASLVTGILNIHGRDVAVYGHDFTVRA
HHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEE
GSMDATNGNKLARLFYMAGEKGIPVIGMNDSAGAYVPAGVGGLDGYAEAFTALRKISGVV
CCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PSIMCMFGFNAGGGSYLPRQGSFVIQPKDTFFGLTGPGVVKSVLGEDVTPEDLGGPKVHG
HHHHHHHCCCCCCCCCCCCCCCEEECCCCCEECCCCHHHHHHHHCCCCCCCCCCCCCCCC
QSGVADLTVEDEVGALRTALQLLNYIPDNNSVMARHQETSDPLDRKTWEINTLLKKAFNS
CCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
PTGFNTPFDVSIIIQQICDHGDYFEMQRDRARNVVTAFGRLGGNVIGFVANNSAVDSGQI
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
DCDAAYKIARFNRFCNIYNIPIIFMEDTTGFLPGREQEARGIVQAGRAMLDSIVDIRTPR
CHHHHHHHHHHHHHCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
ILLILRNAYGGAYASYNNYPTGADLVLALPTTRLAVMGPAGKEFVYKDELRKIRNAVIER
EEEEEECCCCCEECCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VKRGTQERVEAGVKPDLAKLDAEKEAADWLRAEEALLNTRYEKELMNPKEALSLGSISSL
HHCCCHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHH
VMPTDLRKVLGENMNFFLRHYKPGPMQSVQREFH
HCCHHHHHHHCCCCEEEHEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]