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The map label for this gene is yicO [C]

Identifier: 197116938

GI number: 197116938

Start: 652511

End: 653821

Strand: Reverse

Name: yicO [C]

Synonym: Gbem_0540

Alternate gene names: 197116938

Gene position: 653821-652511 (Counterclockwise)

Preceding gene: 197116939

Following gene: 197116937

Centisome position: 14.17

GC content: 62.78

Gene sequence:

>1311_bases
ATGACCTCCCGCATAGCAGCATACTTCCAGTTCCAGCGCTACGGCACCGACATGAAGCGTGAGGTCATCGCAGGACTCAC
CACCTTCCTCACCATGGCGTACATCATCATAGTCAACCCGGCGATCCTGGAAAATGCCGGCATCCCGCGCGGCCCCTCCA
CAACCGCCACCATCATCGCCGCCGTCTTCGGCACCGTACTCATGGCCTTCTTCGCCAACCGTCCCTTCGCCATCGCACCG
TACATGAGCGAAAACGCCTTCATCGCCTTCGTGGTGGTGAAGGTGATGGGCTATTCCTGGCAGACTGCGCTGACCGCCGT
CTTCTTCGCCGGGATCCTCTTCACCCTGCTCACCCTGTTCAAGGTGAGGAGCTGGCTCGCCGAATCGATACCGCTGTCGC
TCAAGTGCGCCTTCGCTACCGGCATCGGCCTCTTCCTCACCTTTATAGGCCTTAACGAGACCGGCATCGTGGTGCTCGGT
GTTCCCGGGGCACCGGTCAAGCTTGGCGACCTCTCCCAACCCTCGGTGCTCCTGGCCGTCTGCGGCCTCCTCCTGACCGT
GGTGCTGATCTCCCGCAAGGTGCTGGGGGCCATGATGATCGGCATCGTCGCCACCACGCTCGCCTCGATCGCGCTCAAGG
TGACCCCGCTGCCGCACTCTTTCGTCAGCCTGCCGCCGGACATCTCCCCGATCCTGTTCCAGCTCGATTTCGCGGGGGCG
CTCTCCCCCGGGTTCTTCCCGATCATCCTGACCATCTTCATCATGGCTTTCCTCGACACCGTCGGGACCTTGCTGGGCCT
TTCCATGCGGGCCGACCTCCTGGACGAGAAGGGGAACCTTCCCGAGATAGAGAAGCCGATGCTCGCCGACGCGCTGGCGA
CGGTCGCGGCGCCGCTTCTGGGGACCACCACCACCGGCGCCTACATCGAGAGCGCGGCAGGGATCGAGGAGGGGGGGCGC
ACCGGCTTCACCGCCCTGGTCACCGCCTTCTTCTTCCTTCTGGCCCTCTTCTTCGCGCCCCTTTTCACCGTGGTCCCGGC
GCACGCCTTCGGCATAGCCCTGATCGTGATCGGTTCCTTCATGATCAGCCCGCTGGCGAAGATCGACTTCGACGACTTCA
CCGAACAGATCCCCGCCTTTCTGACCGTGGTGCTGATGATCTTCACCTACAACATCGGGGTCGGCATGACCGCCGGATTC
ATCGCCTATCCGCTCATGAAGGGCGCCACCGGGCGCATCAAGGAGATGAAAGGGGGGATGTGGGTGCTTGCCCTGCTCTC
CCTCTCCTACTTCATCTTCGGGGCAAAATAG

Upstream 100 bases:

>100_bases
TAGAGGTAGAGGACCGCTTCCTCTTCGGTTGCGGCATGGACATCGCAGGCTACTGGCGCAATCTCCCCGCGCTCTACGCA
ATGAAGGAGCAGAACTAGAA

Downstream 100 bases:

>100_bases
ACAGGCCTCGAAAGAGACACGTCCCCCTCCCGCCACCGGAGGGGGACGCCTCCCCTCCCCCAGAAATCTTTCTAATCTAA
TGAACAACCCGACGCCAAGT

Product: hypoxanthine/guanine transport membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTSRIAAYFQFQRYGTDMKREVIAGLTTFLTMAYIIIVNPAILENAGIPRGPSTTATIIAAVFGTVLMAFFANRPFAIAP
YMSENAFIAFVVVKVMGYSWQTALTAVFFAGILFTLLTLFKVRSWLAESIPLSLKCAFATGIGLFLTFIGLNETGIVVLG
VPGAPVKLGDLSQPSVLLAVCGLLLTVVLISRKVLGAMMIGIVATTLASIALKVTPLPHSFVSLPPDISPILFQLDFAGA
LSPGFFPIILTIFIMAFLDTVGTLLGLSMRADLLDEKGNLPEIEKPMLADALATVAAPLLGTTTTGAYIESAAGIEEGGR
TGFTALVTAFFFLLALFFAPLFTVVPAHAFGIALIVIGSFMISPLAKIDFDDFTEQIPAFLTVVLMIFTYNIGVGMTAGF
IAYPLMKGATGRIKEMKGGMWVLALLSLSYFIFGAK

Sequences:

>Translated_436_residues
MTSRIAAYFQFQRYGTDMKREVIAGLTTFLTMAYIIIVNPAILENAGIPRGPSTTATIIAAVFGTVLMAFFANRPFAIAP
YMSENAFIAFVVVKVMGYSWQTALTAVFFAGILFTLLTLFKVRSWLAESIPLSLKCAFATGIGLFLTFIGLNETGIVVLG
VPGAPVKLGDLSQPSVLLAVCGLLLTVVLISRKVLGAMMIGIVATTLASIALKVTPLPHSFVSLPPDISPILFQLDFAGA
LSPGFFPIILTIFIMAFLDTVGTLLGLSMRADLLDEKGNLPEIEKPMLADALATVAAPLLGTTTTGAYIESAAGIEEGGR
TGFTALVTAFFFLLALFFAPLFTVVPAHAFGIALIVIGSFMISPLAKIDFDDFTEQIPAFLTVVLMIFTYNIGVGMTAGF
IAYPLMKGATGRIKEMKGGMWVLALLSLSYFIFGAK
>Mature_435_residues
TSRIAAYFQFQRYGTDMKREVIAGLTTFLTMAYIIIVNPAILENAGIPRGPSTTATIIAAVFGTVLMAFFANRPFAIAPY
MSENAFIAFVVVKVMGYSWQTALTAVFFAGILFTLLTLFKVRSWLAESIPLSLKCAFATGIGLFLTFIGLNETGIVVLGV
PGAPVKLGDLSQPSVLLAVCGLLLTVVLISRKVLGAMMIGIVATTLASIALKVTPLPHSFVSLPPDISPILFQLDFAGAL
SPGFFPIILTIFIMAFLDTVGTLLGLSMRADLLDEKGNLPEIEKPMLADALATVAAPLLGTTTTGAYIESAAGIEEGGRT
GFTALVTAFFFLLALFFAPLFTVVPAHAFGIALIVIGSFMISPLAKIDFDDFTEQIPAFLTVVLMIFTYNIGVGMTAGFI
AYPLMKGATGRIKEMKGGMWVLALLSLSYFIFGAK

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=417, Percent_Identity=41.4868105515587, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1790150, Length=425, Percent_Identity=40.2352941176471, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790499, Length=435, Percent_Identity=34.9425287356322, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI48994909, Length=399, Percent_Identity=35.0877192982456, Blast_Score=225, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46462; Mature: 46331

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRIAAYFQFQRYGTDMKREVIAGLTTFLTMAYIIIVNPAILENAGIPRGPSTTATIIA
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHH
AVFGTVLMAFFANRPFAIAPYMSENAFIAFVVVKVMGYSWQTALTAVFFAGILFTLLTLF
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVRSWLAESIPLSLKCAFATGIGLFLTFIGLNETGIVVLGVPGAPVKLGDLSQPSVLLAV
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCHHHHHH
CGLLLTVVLISRKVLGAMMIGIVATTLASIALKVTPLPHSFVSLPPDISPILFQLDFAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCCCHHHEEEECCCC
LSPGFFPIILTIFIMAFLDTVGTLLGLSMRADLLDEKGNLPEIEKPMLADALATVAAPLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GTTTTGAYIESAAGIEEGGRTGFTALVTAFFFLLALFFAPLFTVVPAHAFGIALIVIGSF
CCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MISPLAKIDFDDFTEQIPAFLTVVLMIFTYNIGVGMTAGFIAYPLMKGATGRIKEMKGGM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCH
WVLALLSLSYFIFGAK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSRIAAYFQFQRYGTDMKREVIAGLTTFLTMAYIIIVNPAILENAGIPRGPSTTATIIA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHH
AVFGTVLMAFFANRPFAIAPYMSENAFIAFVVVKVMGYSWQTALTAVFFAGILFTLLTLF
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVRSWLAESIPLSLKCAFATGIGLFLTFIGLNETGIVVLGVPGAPVKLGDLSQPSVLLAV
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCHHHHHH
CGLLLTVVLISRKVLGAMMIGIVATTLASIALKVTPLPHSFVSLPPDISPILFQLDFAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCCCHHHEEEECCCC
LSPGFFPIILTIFIMAFLDTVGTLLGLSMRADLLDEKGNLPEIEKPMLADALATVAAPLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GTTTTGAYIESAAGIEEGGRTGFTALVTAFFFLLALFFAPLFTVVPAHAFGIALIVIGSF
CCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MISPLAKIDFDDFTEQIPAFLTVVLMIFTYNIGVGMTAGFIAYPLMKGATGRIKEMKGGM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHCCCH
WVLALLSLSYFIFGAK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]