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The map label for this gene is qor [H]

Identifier: 197116904

GI number: 197116904

Start: 614908

End: 615861

Strand: Direct

Name: qor [H]

Synonym: Gbem_0506

Alternate gene names: 197116904

Gene position: 614908-615861 (Clockwise)

Preceding gene: 197116903

Following gene: 308535168

Centisome position: 13.32

GC content: 53.67

Gene sequence:

>954_bases
ATGAAAGCTGTGACAATAAGCAGGTATGGTGGCAACGAAGTTGTCGAAGTTGCGGATGTGCCGGTGCCTACTCCAGGGGA
AGATGACGTACTCATCAAGGTCCATGCTGCTTCAGTGAATCCTGTGGACTGGAAGATTCGCAACGGCATGCTGAAGCTCT
TTACCGGACGCTCTTTTCCTAAGATTCTCGGCAGTGAATGCGCTGGTGAGGTCGTTGAAACCGGAGCCAACGTGCGGCAG
TTCAAAAAAGGGGATTTTGTCATTGGCTACCCGGGAATAAAAAGGTTGGCTGCCTTTGCTGAGTATGTTTGCGCTGACAA
GGGAAGCACCTTTGTAAAGCCCGGCAATGTCAGCTCCGAGGAAGCATCCACGCTCCCCATTGCCGGGCTGACCGCATTGC
GGGCGCTGCGGGACTTGGGCAAAGTTGCCGAGGGTGGGCACGTCTTGATCAATGGCGCGTCGGGAGGTGTAGGGACATTT
GCCGTACAGATTGCAAAGATCCTTGGCGCGCGTGTCACCGCCGTATGCAGCGCCAGCAATGCAGCCCTGGTGCAAGATCT
CGGTGCCGACCGGGTGTTGGATTATGCGCACGAGGACTTCACCAAAGGTGGCGAGAGGTTCGACGTCGTCTTCGACGCCA
TTGCCAAGCGCTCGTTTGCCGAGTGCAAAAGGGCGATGACGGCAAAGGGAGTCTACGTAAGCACGCTTCCGTCACCTTCC
GTGCTGCTGAACCAGTACCTCACCCGATTTTTCACCCGGAAAACTGCAAAGGCCGTGATGGTTAAGCCCAATGCCGCGGA
TATGGAATGGATGAAGAAATATATCGAAGCAGGCAAACTCAGGGTTGTCGTTGATAAGGTTTTTTCTCTGGAGCAGATAA
AGGAAGCCTTCATCTATAGTGAATCGGGAAAGGCTAAGGGAAAGATTGTTGTCAGGACGGGCGAAAGTGAATAA

Upstream 100 bases:

>100_bases
GAATTGTCTGCACCAATTGCGGTTCCAGCATCCGAGGGCACAAGCCGCAATGACATGAGTCGCAATGACCATGACAGAGA
GGATGGTTTGGGAGACAACG

Downstream 100 bases:

>100_bases
AGCACCTGTAGCCCGAAGAGGTAATAAGAGAGATCCGATGGAGAAAAATGATCAAACAATAGGAACCTTGAGTGAGATCG
TCCGCGCGAGGAGAACGATA

Product: zinc-dependent oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKAVTISRYGGNEVVEVADVPVPTPGEDDVLIKVHAASVNPVDWKIRNGMLKLFTGRSFPKILGSECAGEVVETGANVRQ
FKKGDFVIGYPGIKRLAAFAEYVCADKGSTFVKPGNVSSEEASTLPIAGLTALRALRDLGKVAEGGHVLINGASGGVGTF
AVQIAKILGARVTAVCSASNAALVQDLGADRVLDYAHEDFTKGGERFDVVFDAIAKRSFAECKRAMTAKGVYVSTLPSPS
VLLNQYLTRFFTRKTAKAVMVKPNAADMEWMKKYIEAGKLRVVVDKVFSLEQIKEAFIYSESGKAKGKIVVRTGESE

Sequences:

>Translated_317_residues
MKAVTISRYGGNEVVEVADVPVPTPGEDDVLIKVHAASVNPVDWKIRNGMLKLFTGRSFPKILGSECAGEVVETGANVRQ
FKKGDFVIGYPGIKRLAAFAEYVCADKGSTFVKPGNVSSEEASTLPIAGLTALRALRDLGKVAEGGHVLINGASGGVGTF
AVQIAKILGARVTAVCSASNAALVQDLGADRVLDYAHEDFTKGGERFDVVFDAIAKRSFAECKRAMTAKGVYVSTLPSPS
VLLNQYLTRFFTRKTAKAVMVKPNAADMEWMKKYIEAGKLRVVVDKVFSLEQIKEAFIYSESGKAKGKIVVRTGESE
>Mature_317_residues
MKAVTISRYGGNEVVEVADVPVPTPGEDDVLIKVHAASVNPVDWKIRNGMLKLFTGRSFPKILGSECAGEVVETGANVRQ
FKKGDFVIGYPGIKRLAAFAEYVCADKGSTFVKPGNVSSEEASTLPIAGLTALRALRDLGKVAEGGHVLINGASGGVGTF
AVQIAKILGARVTAVCSASNAALVQDLGADRVLDYAHEDFTKGGERFDVVFDAIAKRSFAECKRAMTAKGVYVSTLPSPS
VLLNQYLTRFFTRKTAKAVMVKPNAADMEWMKKYIEAGKLRVVVDKVFSLEQIKEAFIYSESGKAKGKIVVRTGESE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=354, Percent_Identity=32.2033898305085, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=28.955223880597, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=28.955223880597, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=29.0909090909091, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=29.0909090909091, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=35.4679802955665, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI28557745, Length=368, Percent_Identity=28.2608695652174, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI24308257, Length=345, Percent_Identity=24.6376811594203, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI67078404, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=23.3226837060703, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI41872631, Length=220, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=271, Percent_Identity=27.6752767527675, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=26.0115606936416, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789651, Length=293, Percent_Identity=27.9863481228669, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI226510941, Length=323, Percent_Identity=24.4582043343653, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71987554, Length=354, Percent_Identity=26.8361581920904, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17507255, Length=337, Percent_Identity=28.486646884273, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17536829, Length=186, Percent_Identity=31.1827956989247, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=220, Percent_Identity=26.3636363636364, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=335, Percent_Identity=28.955223880597, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=215, Percent_Identity=31.1627906976744, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24581341, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24581339, Length=363, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550423, Length=244, Percent_Identity=27.4590163934426, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33974; Mature: 33974

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVTISRYGGNEVVEVADVPVPTPGEDDVLIKVHAASVNPVDWKIRNGMLKLFTGRSFP
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCH
KILGSECAGEVVETGANVRQFKKGDFVIGYPGIKRLAAFAEYVCADKGSTFVKPGNVSSE
HHHHHHHHHHHHHCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCCC
EASTLPIAGLTALRALRDLGKVAEGGHVLINGASGGVGTFAVQIAKILGARVTAVCSASN
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
AALVQDLGADRVLDYAHEDFTKGGERFDVVFDAIAKRSFAECKRAMTAKGVYVSTLPSPS
CHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
VLLNQYLTRFFTRKTAKAVMVKPNAADMEWMKKYIEAGKLRVVVDKVFSLEQIKEAFIYS
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCC
ESGKAKGKIVVRTGESE
CCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKAVTISRYGGNEVVEVADVPVPTPGEDDVLIKVHAASVNPVDWKIRNGMLKLFTGRSFP
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCH
KILGSECAGEVVETGANVRQFKKGDFVIGYPGIKRLAAFAEYVCADKGSTFVKPGNVSSE
HHHHHHHHHHHHHCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCCC
EASTLPIAGLTALRALRDLGKVAEGGHVLINGASGGVGTFAVQIAKILGARVTAVCSASN
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
AALVQDLGADRVLDYAHEDFTKGGERFDVVFDAIAKRSFAECKRAMTAKGVYVSTLPSPS
CHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
VLLNQYLTRFFTRKTAKAVMVKPNAADMEWMKKYIEAGKLRVVVDKVFSLEQIKEAFIYS
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCC
ESGKAKGKIVVRTGESE
CCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]