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The map label for this gene is ybaL [H]

Identifier: 197116903

GI number: 197116903

Start: 612249

End: 614003

Strand: Direct

Name: ybaL [H]

Synonym: Gbem_0505

Alternate gene names: 197116903

Gene position: 612249-614003 (Clockwise)

Preceding gene: 197116902

Following gene: 197116904

Centisome position: 13.27

GC content: 57.55

Gene sequence:

>1755_bases
ATGCACAACCTCGATCTCATCATGACAATAACCGGCGGCTTTACGGCAGCACTGCTATTTGGGTATCTTACCCATCGCCT
GGGCATGTCGACGATTGTCGGCTACCTTTTGGCCGGCATTGCCGTCGGATCGCATACCCCTGGTTTTGTCGCGGACCGAG
CCATGGCTGAACAGTTTGCCGAAATCGGTGTCATCCTGCTCATGTTCGGCGTAGGCCTTCAGTTTCACCTGAAGGAGTTA
CTTGAGGTGCGGCGCGTAGCCATACCCGGAGCCCTTTGTCAGAGCGCCGTAGCAACCCTCCTTAGTTGCCTTGTGGCGAG
GTGGCTGGGGTGGGGGTGGTCGGCAGGGATAGTGTTTGGCTTTGCAGTTTCGGTGGCCAGCACGGTGGTTCTACTTCGCG
TCCTGGTTGACAACAACGAGATGCACACTCCGACCGGCCACATCGCAGTGGGGTGGCTGGTCGTCGAGGATATACTGACC
GTGTTTCTGCTGGTAATTCTGCCGATACTGTTCGGCGCTGGTACGGCGGACTCGGCGAGTCTCCCCGCGGCCATCGGCAT
CTCTTTGGCTAAGATAGCACTTCTCGTTGGGCTGACCTTCTGGGTAGGCGGGCGCACCATCCCATGGCTCCTGGAGCGTG
TGGCCGCTACCCATTCGCGCGAACTCTTCACCCTCACCGTCCTGGTTCTTGCCCTTGGGATTGCCGTTGCATCGACAAAG
GTCTTCGGCGTCTCCATGGCGCTAGGCGCATTCCTGGCGGGGATGGTGGTGAAGCAGTCCGACTTCAGCTTCCGCGCAGC
CTCGGAGGCGCTTCCCATGAGGGACGCCTTCGCGGTGCTCTTCTTCGTCTCGGTGGGAATGCTTTTTAACCCCGGGCATC
TGATGCAGGAACCGGGTCTCGTGCTCATTACCTTGGTGATAATCCTGCTGGGGAAGCCGTTGGCCGCGCTGACGATTGTG
CTTGTCCTGAGGTATGCCCCTCGTGTGGCACTCTCAGTTGCCGTCGCCCTGGCTCAGATCGGCGAGTTTTCGTTCATCCT
GGCCACGGCAGGTAAGGACATGGGGGTGTTGGGAGAGAGTGGAGCAAATACTATAGTTGCCGCTGCGATTATCTCGATCA
GCCTCAACCCGCTTTTGTACCGGCTTATTGGTCCCCTGGAGCGGCGGGCAAGGCACACCCGTCTGTGGCAAATACTTGAA
GCAAGGTCAAAACCACATGCACTAGGCGGCGAAGCGGTCCCAGGCCTGCATTCGGTATCCCGCGACCGTGCAATCGTGGT
GGGGTACGGCCCGACAGGAAAAACTCTGGTGCGCCTGCTAGTCGACAACGGAGTTGATCCGTTTGTGGTGGAGATGAACA
TACATATGGTTCGGCAATTACAGGCCGATGGGATTGGAGTAATTTATGGTGACGCAACCAACCGCGATACGCTCTGCGCT
GCCGGGATACAGGATGCCGTTGCCCTCATCCTCACCTCTTCCGGAATGCAAGGGAGTGAGGAGACTATCCAGTTGGCCCG
GGAGATAAACCCGAGACTGCGGATCATCGCCCGCACCACCTATTTGCGGAATATACAAACGCTTCGCGAGGCAGGAGCTG
AAGCGGTTTTTTCAGGTGAGGGTGAGATTGCGCTCAACATGACTGAACACATGTTGCGTAAACTCGGAGCCACTGATGAA
CAGATAAGCCGAGAACGAGACCGAGTCAGAGACGAATTGCTCGGTGGCTCAATGACCGGGCTTAAAGTGACATGA

Upstream 100 bases:

>100_bases
AGCAAGCCCAATCGTTGCGGTGCTTGAGGCAAGGCGGGGCGGATGGGAGTTGGCGGACGGGGACGGCTTAAGTGGAACCA
GTGAGGAGGAACTGTAAAAA

Downstream 100 bases:

>100_bases
CGTTGTAAATTCTTTACCTCGAAGAACAAGGGGATGCCCGTAAATATAATGGGCGTCCCCTTGTTTCATTGTTCCGTGGT
CGTGGTGGGATGGACGGGTG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MHNLDLIMTITGGFTAALLFGYLTHRLGMSTIVGYLLAGIAVGSHTPGFVADRAMAEQFAEIGVILLMFGVGLQFHLKEL
LEVRRVAIPGALCQSAVATLLSCLVARWLGWGWSAGIVFGFAVSVASTVVLLRVLVDNNEMHTPTGHIAVGWLVVEDILT
VFLLVILPILFGAGTADSASLPAAIGISLAKIALLVGLTFWVGGRTIPWLLERVAATHSRELFTLTVLVLALGIAVASTK
VFGVSMALGAFLAGMVVKQSDFSFRAASEALPMRDAFAVLFFVSVGMLFNPGHLMQEPGLVLITLVIILLGKPLAALTIV
LVLRYAPRVALSVAVALAQIGEFSFILATAGKDMGVLGESGANTIVAAAIISISLNPLLYRLIGPLERRARHTRLWQILE
ARSKPHALGGEAVPGLHSVSRDRAIVVGYGPTGKTLVRLLVDNGVDPFVVEMNIHMVRQLQADGIGVIYGDATNRDTLCA
AGIQDAVALILTSSGMQGSEETIQLAREINPRLRIIARTTYLRNIQTLREAGAEAVFSGEGEIALNMTEHMLRKLGATDE
QISRERDRVRDELLGGSMTGLKVT

Sequences:

>Translated_584_residues
MHNLDLIMTITGGFTAALLFGYLTHRLGMSTIVGYLLAGIAVGSHTPGFVADRAMAEQFAEIGVILLMFGVGLQFHLKEL
LEVRRVAIPGALCQSAVATLLSCLVARWLGWGWSAGIVFGFAVSVASTVVLLRVLVDNNEMHTPTGHIAVGWLVVEDILT
VFLLVILPILFGAGTADSASLPAAIGISLAKIALLVGLTFWVGGRTIPWLLERVAATHSRELFTLTVLVLALGIAVASTK
VFGVSMALGAFLAGMVVKQSDFSFRAASEALPMRDAFAVLFFVSVGMLFNPGHLMQEPGLVLITLVIILLGKPLAALTIV
LVLRYAPRVALSVAVALAQIGEFSFILATAGKDMGVLGESGANTIVAAAIISISLNPLLYRLIGPLERRARHTRLWQILE
ARSKPHALGGEAVPGLHSVSRDRAIVVGYGPTGKTLVRLLVDNGVDPFVVEMNIHMVRQLQADGIGVIYGDATNRDTLCA
AGIQDAVALILTSSGMQGSEETIQLAREINPRLRIIARTTYLRNIQTLREAGAEAVFSGEGEIALNMTEHMLRKLGATDE
QISRERDRVRDELLGGSMTGLKVT
>Mature_584_residues
MHNLDLIMTITGGFTAALLFGYLTHRLGMSTIVGYLLAGIAVGSHTPGFVADRAMAEQFAEIGVILLMFGVGLQFHLKEL
LEVRRVAIPGALCQSAVATLLSCLVARWLGWGWSAGIVFGFAVSVASTVVLLRVLVDNNEMHTPTGHIAVGWLVVEDILT
VFLLVILPILFGAGTADSASLPAAIGISLAKIALLVGLTFWVGGRTIPWLLERVAATHSRELFTLTVLVLALGIAVASTK
VFGVSMALGAFLAGMVVKQSDFSFRAASEALPMRDAFAVLFFVSVGMLFNPGHLMQEPGLVLITLVIILLGKPLAALTIV
LVLRYAPRVALSVAVALAQIGEFSFILATAGKDMGVLGESGANTIVAAAIISISLNPLLYRLIGPLERRARHTRLWQILE
ARSKPHALGGEAVPGLHSVSRDRAIVVGYGPTGKTLVRLLVDNGVDPFVVEMNIHMVRQLQADGIGVIYGDATNRDTLCA
AGIQDAVALILTSSGMQGSEETIQLAREINPRLRIIARTTYLRNIQTLREAGAEAVFSGEGEIALNMTEHMLRKLGATDE
QISRERDRVRDELLGGSMTGLKVT

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=388, Percent_Identity=27.0618556701031, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1786685, Length=551, Percent_Identity=44.6460980036298, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1786232, Length=544, Percent_Identity=29.2279411764706, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1789749, Length=550, Percent_Identity=27.8181818181818, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 62270; Mature: 62270

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLDLIMTITGGFTAALLFGYLTHRLGMSTIVGYLLAGIAVGSHTPGFVADRAMAEQFA
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EIGVILLMFGVGLQFHLKELLEVRRVAIPGALCQSAVATLLSCLVARWLGWGWSAGIVFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FAVSVASTVVLLRVLVDNNEMHTPTGHIAVGWLVVEDILTVFLLVILPILFGAGTADSAS
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPAAIGISLAKIALLVGLTFWVGGRTIPWLLERVAATHSRELFTLTVLVLALGIAVASTK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFGVSMALGAFLAGMVVKQSDFSFRAASEALPMRDAFAVLFFVSVGMLFNPGHLMQEPGL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCH
VLITLVIILLGKPLAALTIVLVLRYAPRVALSVAVALAQIGEFSFILATAGKDMGVLGES
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
GANTIVAAAIISISLNPLLYRLIGPLERRARHTRLWQILEARSKPHALGGEAVPGLHSVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCC
RDRAIVVGYGPTGKTLVRLLVDNGVDPFVVEMNIHMVRQLQADGIGVIYGDATNRDTLCA
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCEEEECCCCCCCCHHH
AGIQDAVALILTSSGMQGSEETIQLAREINPRLRIIARTTYLRNIQTLREAGAEAVFSGE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEECCC
GEIALNMTEHMLRKLGATDEQISRERDRVRDELLGGSMTGLKVT
CCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEC
>Mature Secondary Structure
MHNLDLIMTITGGFTAALLFGYLTHRLGMSTIVGYLLAGIAVGSHTPGFVADRAMAEQFA
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EIGVILLMFGVGLQFHLKELLEVRRVAIPGALCQSAVATLLSCLVARWLGWGWSAGIVFG
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FAVSVASTVVLLRVLVDNNEMHTPTGHIAVGWLVVEDILTVFLLVILPILFGAGTADSAS
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LPAAIGISLAKIALLVGLTFWVGGRTIPWLLERVAATHSRELFTLTVLVLALGIAVASTK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VFGVSMALGAFLAGMVVKQSDFSFRAASEALPMRDAFAVLFFVSVGMLFNPGHLMQEPGL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCH
VLITLVIILLGKPLAALTIVLVLRYAPRVALSVAVALAQIGEFSFILATAGKDMGVLGES
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
GANTIVAAAIISISLNPLLYRLIGPLERRARHTRLWQILEARSKPHALGGEAVPGLHSVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCC
RDRAIVVGYGPTGKTLVRLLVDNGVDPFVVEMNIHMVRQLQADGIGVIYGDATNRDTLCA
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCEEEECCCCCCCCHHH
AGIQDAVALILTSSGMQGSEETIQLAREINPRLRIIARTTYLRNIQTLREAGAEAVFSGE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEECCC
GEIALNMTEHMLRKLGATDEQISRERDRVRDELLGGSMTGLKVT
CCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]