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The map label for this gene is dinB [H]

Identifier: 197116898

GI number: 197116898

Start: 606708

End: 607961

Strand: Reverse

Name: dinB [H]

Synonym: Gbem_0500

Alternate gene names: 197116898

Gene position: 607961-606708 (Counterclockwise)

Preceding gene: 197116899

Following gene: 197116897

Centisome position: 13.17

GC content: 65.95

Gene sequence:

>1254_bases
GTGGACCGGGAAATCCTCCACATAACTGTTCCCGCTTTTCCCATCGCGCTGGCCCGGGTCGTCGACTCGAACCTGCGCGG
ACGGCCGGTGGCGGTGGCTCCGCTCAACTCGGAACGGGCGCTGCTGCAGTGCATCTCTGCGGAGGCTGCGGCGGAGGGGG
TGCACGCGGGGACTCCCATCTACCACGCTCGCAAGTCCTGCCCCGCGCTCATCGTGATCGCTCCGGACCCTCACCTGATG
GCGAAGGGAAGCCAAGCGCTACAGGATCTCTCGGCCGAATTCACCCCTATCGTGGAACCGGGGGCCGGGCGGGCGTTCCT
GGATCTCACCGCTTCGCGCAGGCTCTTCGGGCCGGCGCGGGATGTCGCGGCCAGGCTGGAGAAGGCGATAGCGAACAGGA
TGGGGCTGGAGGCGATGGCCGGGGCGGGGGTGAACAAGCTGGTCTCGCGGGTGGCTGCGGATGTGATGCAGGAGGCGGGG
GTCTACGACGTGTTCCATGGGGCGGAGCGGAGCTTTCTGGCGCCCTTTCCTGTTTCGGTGCTGCCCGGGGTGGGGGAATC
GCGGCAGGCTCTGCTCTTTCGGGATCTGAACCTGCAGCGGGTGGAGCAGGTGGCGTCGCTGTCGATGCCGCAACTCCGCC
TTGCTGTCGGCCCTTTTGCGCCTCTTTTGCATGACCGCTCCTGCGGCATCGACAGGTCTCCGGTTCAACCTCCCAGGCTC
TCCACGGAGATCGTGGAGGAGGGGCTGCTGGACCAGGAGGAGAACGACGACGCGATCCTGCTGTCGGAGCTGCTGCGGTT
GGTGGAGGCATGCGGGCTTCGGTTGCGGCGGCTTAGGAAGGGAGCACGCAAGCTGACGCTTTCGGTGATGTACGCGGACG
GGGTGAGCCAGCAGGGAAAGAAGGTGCTGCCGGTGCCGACTTCGCTGGACCTGCAGTTGCTGGCGGCGGTGGAGGATCTC
TTCTTCACTACCTGCAAACGGCGGCAGAGGGTGAAGGGTTTGCGGCTTAGTTGCGACCAGGTGGCGGAGGACGCGGGACA
GATGGACCTGTTCGCGCCGGCGACGGCCCAGGTGTCGCAGAAGCAGGCCGATTTGCAGGAGACGCTGGACCTCTTGCGGG
AAAAGCATGGGCGCGACGCGGTGCGCTGGGGCAAGGGGCTGGCGGCACGCCGTGAGGCGACTATGGCCAGCGAGCCGCCG
CCGGAGTGGGATCCGGAGCAGAATAAATATATGACTTTGACCAGTAGAAGCTAA

Upstream 100 bases:

>100_bases
TGCAGCCGGCGAACTCGGCGATGAGCCCCATCATGGTGACGGAAGACGACGAGTTTCATATCAGGGGCGTGCTGGTGGGC
TCTATGAGGTTTTATAAGAA

Downstream 100 bases:

>100_bases
AAGCACTCACCACAGAGGAAACTTTGAAAGGCGGAACACAGAGGTCGCTGAGGATCACGGAGGTCACAGAGGAAACCGAA
AGACTTTGGGTTAACCCCAA

Product: DNA polymerase IV kappa

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDREILHITVPAFPIALARVVDSNLRGRPVAVAPLNSERALLQCISAEAAAEGVHAGTPIYHARKSCPALIVIAPDPHLM
AKGSQALQDLSAEFTPIVEPGAGRAFLDLTASRRLFGPARDVAARLEKAIANRMGLEAMAGAGVNKLVSRVAADVMQEAG
VYDVFHGAERSFLAPFPVSVLPGVGESRQALLFRDLNLQRVEQVASLSMPQLRLAVGPFAPLLHDRSCGIDRSPVQPPRL
STEIVEEGLLDQEENDDAILLSELLRLVEACGLRLRRLRKGARKLTLSVMYADGVSQQGKKVLPVPTSLDLQLLAAVEDL
FFTTCKRRQRVKGLRLSCDQVAEDAGQMDLFAPATAQVSQKQADLQETLDLLREKHGRDAVRWGKGLAARREATMASEPP
PEWDPEQNKYMTLTSRS

Sequences:

>Translated_417_residues
MDREILHITVPAFPIALARVVDSNLRGRPVAVAPLNSERALLQCISAEAAAEGVHAGTPIYHARKSCPALIVIAPDPHLM
AKGSQALQDLSAEFTPIVEPGAGRAFLDLTASRRLFGPARDVAARLEKAIANRMGLEAMAGAGVNKLVSRVAADVMQEAG
VYDVFHGAERSFLAPFPVSVLPGVGESRQALLFRDLNLQRVEQVASLSMPQLRLAVGPFAPLLHDRSCGIDRSPVQPPRL
STEIVEEGLLDQEENDDAILLSELLRLVEACGLRLRRLRKGARKLTLSVMYADGVSQQGKKVLPVPTSLDLQLLAAVEDL
FFTTCKRRQRVKGLRLSCDQVAEDAGQMDLFAPATAQVSQKQADLQETLDLLREKHGRDAVRWGKGLAARREATMASEPP
PEWDPEQNKYMTLTSRS
>Mature_417_residues
MDREILHITVPAFPIALARVVDSNLRGRPVAVAPLNSERALLQCISAEAAAEGVHAGTPIYHARKSCPALIVIAPDPHLM
AKGSQALQDLSAEFTPIVEPGAGRAFLDLTASRRLFGPARDVAARLEKAIANRMGLEAMAGAGVNKLVSRVAADVMQEAG
VYDVFHGAERSFLAPFPVSVLPGVGESRQALLFRDLNLQRVEQVASLSMPQLRLAVGPFAPLLHDRSCGIDRSPVQPPRL
STEIVEEGLLDQEENDDAILLSELLRLVEACGLRLRRLRKGARKLTLSVMYADGVSQQGKKVLPVPTSLDLQLLAAVEDL
FFTTCKRRQRVKGLRLSCDQVAEDAGQMDLFAPATAQVSQKQADLQETLDLLREKHGRDAVRWGKGLAARREATMASEPP
PEWDPEQNKYMTLTSRS

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=252, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI84043967, Length=252, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786425, Length=243, Percent_Identity=26.3374485596708, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45401; Mature: 45401

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREILHITVPAFPIALARVVDSNLRGRPVAVAPLNSERALLQCISAEAAAEGVHAGTPI
CCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCH
YHARKSCPALIVIAPDPHLMAKGSQALQDLSAEFTPIVEPGAGRAFLDLTASRRLFGPAR
HHHHCCCCEEEEECCCCCHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCHHH
DVAARLEKAIANRMGLEAMAGAGVNKLVSRVAADVMQEAGVYDVFHGAERSFLAPFPVSV
HHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHH
LPGVGESRQALLFRDLNLQRVEQVASLSMPQLRLAVGPFAPLLHDRSCGIDRSPVQPPRL
CCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCC
STEIVEEGLLDQEENDDAILLSELLRLVEACGLRLRRLRKGARKLTLSVMYADGVSQQGK
CHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
KVLPVPTSLDLQLLAAVEDLFFTTCKRRQRVKGLRLSCDQVAEDAGQMDLFAPATAQVSQ
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCHHHHHH
KQADLQETLDLLREKHGRDAVRWGKGLAARREATMASEPPPEWDPEQNKYMTLTSRS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MDREILHITVPAFPIALARVVDSNLRGRPVAVAPLNSERALLQCISAEAAAEGVHAGTPI
CCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCH
YHARKSCPALIVIAPDPHLMAKGSQALQDLSAEFTPIVEPGAGRAFLDLTASRRLFGPAR
HHHHCCCCEEEEECCCCCHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCHHH
DVAARLEKAIANRMGLEAMAGAGVNKLVSRVAADVMQEAGVYDVFHGAERSFLAPFPVSV
HHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHH
LPGVGESRQALLFRDLNLQRVEQVASLSMPQLRLAVGPFAPLLHDRSCGIDRSPVQPPRL
CCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCC
STEIVEEGLLDQEENDDAILLSELLRLVEACGLRLRRLRKGARKLTLSVMYADGVSQQGK
CHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
KVLPVPTSLDLQLLAAVEDLFFTTCKRRQRVKGLRLSCDQVAEDAGQMDLFAPATAQVSQ
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCHHHHHH
KQADLQETLDLLREKHGRDAVRWGKGLAARREATMASEPPPEWDPEQNKYMTLTSRS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA