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The map label for this gene is atoS [C]

Identifier: 197116896

GI number: 197116896

Start: 601353

End: 603422

Strand: Direct

Name: atoS [C]

Synonym: Gbem_0498

Alternate gene names: 197116896

Gene position: 601353-603422 (Clockwise)

Preceding gene: 197116895

Following gene: 197116900

Centisome position: 13.03

GC content: 60.19

Gene sequence:

>2070_bases
ATGTCCGATCGACCACTTTACAACAGCAAGATAATCAACAACTTCGTCGCGCTGCTGAAGAAAAAGCATGCGGACGTGGA
CGTGCGCGAGCTTTTGAACTATGCGGAGATAAGCCCGTACGAGCTGAGCGACGAAGGGCACTGGCTCACCCAGCGGCAGG
TCGACCGTTTCCACGACAAGATGTCCTATCTCCTGGGGGGCAAAGAACTAGCCCGGGAAGGAGGGCGTTACGCCGCCTCC
GAAGAGGCATTGGGCGTGATGGCCAAGTACACCTTCGGCTTCATCGGGCCGGCCAACACCCTGGTCGCCATAGGCAAATG
CGCCTCCAACTTCACCCGTTCCGCCGTCTATCAATCCCGCAAGCTCGCCGACAACAAGGTGGAGATCACGGTAACCCCCC
ATTCCGACGTGGAGGAAAAGCCTTTCCAGTGCGAAAACCGCATCGGCTTTTTCGAGGCGATCGTCCAGATGTTCGACCAC
GACATCCCCTCCGTCGAACACCCCGAGTGCATCTTCAAGGGGGGCTCCTGCTGCAGGTACATCGTCTCCTGGAAGAAGAC
CTGGGCCGGCAAGATCCGGTTGGTCAGAAACCTCCAGGTGCCGGTCGTGCTCGTACTCTACGGGGTGCTCCACCACTTCT
ACCGAATCGGGCACCTGGGCGAGATGCTGGTAGCGCTCGCCTTCATGCAACTGGGCGCGTCCTACCTCGCCGAGCGGCTG
GAGAAGAAAGAGATACTCGCCACCCTGGCCGGCGTGCAGGAGTCGACGGAGCAGATGGTCGACCAGATCGGCGTCAACTA
CAACAACGCCCGGATGGTAAACGAGGTGGGGCAGGCCCTGAGCACGCAAAGCGGCATAGACGAGGTGCTGCAGAATGTGA
TCGGCGCCCTCGAGAAGCGGCTGGGGTATGACCGGTGCCTTATCATGCTGGCGGACAAGAACAAATCGTGCCTTAAGTTC
CGCACCGGGGTCGGCATCAACGACAAGCAACTGAAAGCGCTGAAAAAGGCCTCCTTCGATCTCACCAACCCTGGCGCCAA
AGGGGCCTTCGTAACCTGCTTCCGGGAACAAAGGACGATGTTCGTCGACTTTTCCGAGGTGACGCACATTCACTCCGAGC
AGAGCATCAACCTCTCCGAGGTGCTGGAGGCGCAATCCTTCATCTGTTGCGCCATTGTCTTCGAGGGAGAGTCGCTGGGT
ATCCTGGCGGTGGACAACATGAAGACCCAGCGGCCGCTGACCCAAAGCGACATGAGCCTTTTGACCGGTCTCGCGCCGGT
CATCGGCATGAGCCTTCGCAACGCCATGCACCTGGAGCGCGAAAGGAGGATGGCGGAGCAGATCAGGCAGTCGCAGAAGA
TGGAAGCCGTCGGGGTGCTGGCAGGAGGAATCGCGCACGATTTCAACAACCTGCTGACCGGTATGATCGGGTACGTCAGC
CTGGCGCTGATGACCATTAAGGAGGAGGACCCCGCCACGAAGTACCTGGACCAGGTCGTCTCCGCCGCCGACCGGGCCGC
CGACCTCACCCAGAGGCTCCTCGCCTTCAGCAGAAAGCAGATCAACCACCCGGAACCGGTGGACCTGAACCAGATCGTGA
ACAACGTGAGAAAGCTCCTGAGCAGACTGGTTACGGCGAAAATCGAGCTGAAGGTCGAACCGAGCGAGGGGATGTTGCCG
GTGGTCGCGGATTCGAGCCAGATCGACCAGATGGTGATGAACCTGGTCACCAACGCGCGGGACGCCATGCCCACCGGGGG
GACGCTGACCATAACCACCGAAGCGATGGAGCTGACCGAGGAGTGGGTGGAGTCGCACGGATACGGCAGTATCGGCTCTT
ACGCCGTTTTATCCGTCACCGACACGGGGACCGGCATGGACGAGGCGACCAGGGCCCACGTTCTCGAGCCGTTTTTTACC
ACGAAGGAAGTGGGGAAGGGGAGCGGGTTAGGTCTGGCCATCGTGTACGGGATCGTGAAGCAGCACGAAGGGCACCTGGA
GATCTACAGCAAGCCTGGCGCAGGGACCACCTTGAACGTCTATCTCCCGCTCATTGCACCTGCGCCCTAG

Upstream 100 bases:

>100_bases
TCGCCCCTAAAGAAAACGCGTAGTTTACCGATACGGGACAGTGGTCCTCATTAAACCAAAAGGACCACCGCCGGAAGCTT
ACGGCCAGGAACCTTGCCCG

Downstream 100 bases:

>100_bases
CTTCCCTCACCCGTCCAGAAAACCGACCCACTTCACCCTGAGCGTCGCCACTCCGAACTCCTCTTCCACTATCCCTTTGA
GCAGGTAGGGGCGCCGCTGC

Product: GAF domain-containing sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MSDRPLYNSKIINNFVALLKKKHADVDVRELLNYAEISPYELSDEGHWLTQRQVDRFHDKMSYLLGGKELAREGGRYAAS
EEALGVMAKYTFGFIGPANTLVAIGKCASNFTRSAVYQSRKLADNKVEITVTPHSDVEEKPFQCENRIGFFEAIVQMFDH
DIPSVEHPECIFKGGSCCRYIVSWKKTWAGKIRLVRNLQVPVVLVLYGVLHHFYRIGHLGEMLVALAFMQLGASYLAERL
EKKEILATLAGVQESTEQMVDQIGVNYNNARMVNEVGQALSTQSGIDEVLQNVIGALEKRLGYDRCLIMLADKNKSCLKF
RTGVGINDKQLKALKKASFDLTNPGAKGAFVTCFREQRTMFVDFSEVTHIHSEQSINLSEVLEAQSFICCAIVFEGESLG
ILAVDNMKTQRPLTQSDMSLLTGLAPVIGMSLRNAMHLERERRMAEQIRQSQKMEAVGVLAGGIAHDFNNLLTGMIGYVS
LALMTIKEEDPATKYLDQVVSAADRAADLTQRLLAFSRKQINHPEPVDLNQIVNNVRKLLSRLVTAKIELKVEPSEGMLP
VVADSSQIDQMVMNLVTNARDAMPTGGTLTITTEAMELTEEWVESHGYGSIGSYAVLSVTDTGTGMDEATRAHVLEPFFT
TKEVGKGSGLGLAIVYGIVKQHEGHLEIYSKPGAGTTLNVYLPLIAPAP

Sequences:

>Translated_689_residues
MSDRPLYNSKIINNFVALLKKKHADVDVRELLNYAEISPYELSDEGHWLTQRQVDRFHDKMSYLLGGKELAREGGRYAAS
EEALGVMAKYTFGFIGPANTLVAIGKCASNFTRSAVYQSRKLADNKVEITVTPHSDVEEKPFQCENRIGFFEAIVQMFDH
DIPSVEHPECIFKGGSCCRYIVSWKKTWAGKIRLVRNLQVPVVLVLYGVLHHFYRIGHLGEMLVALAFMQLGASYLAERL
EKKEILATLAGVQESTEQMVDQIGVNYNNARMVNEVGQALSTQSGIDEVLQNVIGALEKRLGYDRCLIMLADKNKSCLKF
RTGVGINDKQLKALKKASFDLTNPGAKGAFVTCFREQRTMFVDFSEVTHIHSEQSINLSEVLEAQSFICCAIVFEGESLG
ILAVDNMKTQRPLTQSDMSLLTGLAPVIGMSLRNAMHLERERRMAEQIRQSQKMEAVGVLAGGIAHDFNNLLTGMIGYVS
LALMTIKEEDPATKYLDQVVSAADRAADLTQRLLAFSRKQINHPEPVDLNQIVNNVRKLLSRLVTAKIELKVEPSEGMLP
VVADSSQIDQMVMNLVTNARDAMPTGGTLTITTEAMELTEEWVESHGYGSIGSYAVLSVTDTGTGMDEATRAHVLEPFFT
TKEVGKGSGLGLAIVYGIVKQHEGHLEIYSKPGAGTTLNVYLPLIAPAP
>Mature_688_residues
SDRPLYNSKIINNFVALLKKKHADVDVRELLNYAEISPYELSDEGHWLTQRQVDRFHDKMSYLLGGKELAREGGRYAASE
EALGVMAKYTFGFIGPANTLVAIGKCASNFTRSAVYQSRKLADNKVEITVTPHSDVEEKPFQCENRIGFFEAIVQMFDHD
IPSVEHPECIFKGGSCCRYIVSWKKTWAGKIRLVRNLQVPVVLVLYGVLHHFYRIGHLGEMLVALAFMQLGASYLAERLE
KKEILATLAGVQESTEQMVDQIGVNYNNARMVNEVGQALSTQSGIDEVLQNVIGALEKRLGYDRCLIMLADKNKSCLKFR
TGVGINDKQLKALKKASFDLTNPGAKGAFVTCFREQRTMFVDFSEVTHIHSEQSINLSEVLEAQSFICCAIVFEGESLGI
LAVDNMKTQRPLTQSDMSLLTGLAPVIGMSLRNAMHLERERRMAEQIRQSQKMEAVGVLAGGIAHDFNNLLTGMIGYVSL
ALMTIKEEDPATKYLDQVVSAADRAADLTQRLLAFSRKQINHPEPVDLNQIVNNVRKLLSRLVTAKIELKVEPSEGMLPV
VADSSQIDQMVMNLVTNARDAMPTGGTLTITTEAMELTEEWVESHGYGSIGSYAVLSVTDTGTGMDEATRAHVLEPFFTT
KEVGKGSGLGLAIVYGIVKQHEGHLEIYSKPGAGTTLNVYLPLIAPAP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790436, Length=295, Percent_Identity=28.4745762711864, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790300, Length=266, Percent_Identity=29.6992481203008, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76161; Mature: 76029

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRPLYNSKIINNFVALLKKKHADVDVRELLNYAEISPYELSDEGHWLTQRQVDRFHDK
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHH
MSYLLGGKELAREGGRYAASEEALGVMAKYTFGFIGPANTLVAIGKCASNFTRSAVYQSR
HHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLADNKVEITVTPHSDVEEKPFQCENRIGFFEAIVQMFDHDIPSVEHPECIFKGGSCCRY
HCCCCEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHH
IVSWKKTWAGKIRLVRNLQVPVVLVLYGVLHHFYRIGHLGEMLVALAFMQLGASYLAERL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKKEILATLAGVQESTEQMVDQIGVNYNNARMVNEVGQALSTQSGIDEVLQNVIGALEKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LGYDRCLIMLADKNKSCLKFRTGVGINDKQLKALKKASFDLTNPGAKGAFVTCFREQRTM
CCCCEEEEEEECCCCCHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEE
FVDFSEVTHIHSEQSINLSEVLEAQSFICCAIVFEGESLGILAVDNMKTQRPLTQSDMSL
EEEHHHHHHHCCCCCCCHHHHHHHHCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHH
LTGLAPVIGMSLRNAMHLERERRMAEQIRQSQKMEAVGVLAGGIAHDFNNLLTGMIGYVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALMTIKEEDPATKYLDQVVSAADRAADLTQRLLAFSRKQINHPEPVDLNQIVNNVRKLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SRLVTAKIELKVEPSEGMLPVVADSSQIDQMVMNLVTNARDAMPTGGTLTITTEAMELTE
HHHHCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
EWVESHGYGSIGSYAVLSVTDTGTGMDEATRAHVLEPFFTTKEVGKGSGLGLAIVYGIVK
HHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHH
QHEGHLEIYSKPGAGTTLNVYLPLIAPAP
CCCCCEEEEECCCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
SDRPLYNSKIINNFVALLKKKHADVDVRELLNYAEISPYELSDEGHWLTQRQVDRFHDK
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHH
MSYLLGGKELAREGGRYAASEEALGVMAKYTFGFIGPANTLVAIGKCASNFTRSAVYQSR
HHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KLADNKVEITVTPHSDVEEKPFQCENRIGFFEAIVQMFDHDIPSVEHPECIFKGGSCCRY
HCCCCEEEEEECCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHH
IVSWKKTWAGKIRLVRNLQVPVVLVLYGVLHHFYRIGHLGEMLVALAFMQLGASYLAERL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKKEILATLAGVQESTEQMVDQIGVNYNNARMVNEVGQALSTQSGIDEVLQNVIGALEKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LGYDRCLIMLADKNKSCLKFRTGVGINDKQLKALKKASFDLTNPGAKGAFVTCFREQRTM
CCCCEEEEEEECCCCCHHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEE
FVDFSEVTHIHSEQSINLSEVLEAQSFICCAIVFEGESLGILAVDNMKTQRPLTQSDMSL
EEEHHHHHHHCCCCCCCHHHHHHHHCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHH
LTGLAPVIGMSLRNAMHLERERRMAEQIRQSQKMEAVGVLAGGIAHDFNNLLTGMIGYVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALMTIKEEDPATKYLDQVVSAADRAADLTQRLLAFSRKQINHPEPVDLNQIVNNVRKLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SRLVTAKIELKVEPSEGMLPVVADSSQIDQMVMNLVTNARDAMPTGGTLTITTEAMELTE
HHHHCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
EWVESHGYGSIGSYAVLSVTDTGTGMDEATRAHVLEPFFTTKEVGKGSGLGLAIVYGIVK
HHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHH
QHEGHLEIYSKPGAGTTLNVYLPLIAPAP
CCCCCEEEEECCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA