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The map label for this gene is murB-1 [H]

Identifier: 197116891

GI number: 197116891

Start: 595559

End: 596461

Strand: Direct

Name: murB-1 [H]

Synonym: Gbem_0493

Alternate gene names: 197116891

Gene position: 595559-596461 (Clockwise)

Preceding gene: 197116890

Following gene: 197116892

Centisome position: 12.9

GC content: 65.23

Gene sequence:

>903_bases
TTGACACGGGGCGAGCTCGAACAAGCGGTCCAGGGGGTGCGCGGCACGGTCAAGTGGGACGAGCCGATGTGGCAGCACAC
CTCCCTTAAAGTCGGGGGTCCGGCGGATCTTTACTTCGAGCCCGCCGATCTGCCCGACCTTCACGAGACCGTGGAGAAGC
TCCTCGCCGCGAAGATCCCTTACCTGGTGCTGGGAGGGGGGTACAACCTGCTGGTGCGCGACGGCGGCATCAGAGGGTGC
GTCATCTCGCTCAAGAAACTGGACACCCTGGAGATGCAGCCGGGCGCGAGACTCGAAGTGGGCGCGGGGGTAACCAACTC
CACCCTCTGCCGCTTCGCCGCCGAGCATTGCCTTGGGGGGATGGAATTTCTCAGCGGCATTCCCGGAAGCTTCGGCGGAG
CGCTCACCATGAACGCCGGCGCCCAGGGTGGCGAGACGCTGCAGCGGGTCGAGACGCTCATCACTTTGCGTGAGGGAAAG
CTCTTGGTGCGCAAAGCCGCTGAGCTGGAATTCGGTTACCGCTACTTGAGGCTTTTGCCGGGAGAGATCGTCCTGGGGGC
GAAGCTCAGGCTCGAACCTGCCGAACGCCGCATCATCGAGGAGCGGATGCAGGCCAACATCGCCAGAAGAAGCGGGACGC
AGCGGGTCACCTATCCCAATGCCGGGTCCTTCTTCAAGAACCCGTCGGGGCGGCACGCCTGGGAGCTGATCGACCGGGCC
GGCATGCGCGGCGTCACCGTCGGCGGTGCTCAGGTCTCAGAGGCGCACACCAACTTCCTGGTCAATCGCGGCGGCGCGTG
TGCCGCGGACTTCACTTCGCTCGCGGCGCTGGTGAAGCTGAGGGTGAAGGAGACCAGCGGCGTCGACCTCGAGGAAGAGG
TCCGCCTGGTAGGCGAAGAGTAG

Upstream 100 bases:

>100_bases
TTGCTCCCGGCGACATCCTGCTGACCCTTGGGGCCGGCAACGTCTGGCAGGTGGGAGAGACCATGCTGCTGCGGTTGAAG
GCCGCGAAGGAGAGCTGAGG

Downstream 100 bases:

>100_bases
AAAATTAAGGTGAACTCTCCCCTCCCTTGACGGGAGGGGCAGGGGGTGGGTGAAGCCGCACGGTATGGGAATGATGGCAC
CTTCCCCCACCCCCTAACCC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTRGELEQAVQGVRGTVKWDEPMWQHTSLKVGGPADLYFEPADLPDLHETVEKLLAAKIPYLVLGGGYNLLVRDGGIRGC
VISLKKLDTLEMQPGARLEVGAGVTNSTLCRFAAEHCLGGMEFLSGIPGSFGGALTMNAGAQGGETLQRVETLITLREGK
LLVRKAAELEFGYRYLRLLPGEIVLGAKLRLEPAERRIIEERMQANIARRSGTQRVTYPNAGSFFKNPSGRHAWELIDRA
GMRGVTVGGAQVSEAHTNFLVNRGGACAADFTSLAALVKLRVKETSGVDLEEEVRLVGEE

Sequences:

>Translated_300_residues
MTRGELEQAVQGVRGTVKWDEPMWQHTSLKVGGPADLYFEPADLPDLHETVEKLLAAKIPYLVLGGGYNLLVRDGGIRGC
VISLKKLDTLEMQPGARLEVGAGVTNSTLCRFAAEHCLGGMEFLSGIPGSFGGALTMNAGAQGGETLQRVETLITLREGK
LLVRKAAELEFGYRYLRLLPGEIVLGAKLRLEPAERRIIEERMQANIARRSGTQRVTYPNAGSFFKNPSGRHAWELIDRA
GMRGVTVGGAQVSEAHTNFLVNRGGACAADFTSLAALVKLRVKETSGVDLEEEVRLVGEE
>Mature_299_residues
TRGELEQAVQGVRGTVKWDEPMWQHTSLKVGGPADLYFEPADLPDLHETVEKLLAAKIPYLVLGGGYNLLVRDGGIRGCV
ISLKKLDTLEMQPGARLEVGAGVTNSTLCRFAAEHCLGGMEFLSGIPGSFGGALTMNAGAQGGETLQRVETLITLREGKL
LVRKAAELEFGYRYLRLLPGEIVLGAKLRLEPAERRIIEERMQANIARRSGTQRVTYPNAGSFFKNPSGRHAWELIDRAG
MRGVTVGGAQVSEAHTNFLVNRGGACAADFTSLAALVKLRVKETSGVDLEEEVRLVGEE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32516; Mature: 32385

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGELEQAVQGVRGTVKWDEPMWQHTSLKVGGPADLYFEPADLPDLHETVEKLLAAKIP
CCHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHCCC
YLVLGGGYNLLVRDGGIRGCVISLKKLDTLEMQPGARLEVGAGVTNSTLCRFAAEHCLGG
EEEECCCEEEEEECCCCCEEEEEEHHCCEEECCCCCEEEECCCCCHHHHHHHHHHHHCCH
MEFLSGIPGSFGGALTMNAGAQGGETLQRVETLITLREGKLLVRKAAELEFGYRYLRLLP
HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCC
GEIVLGAKLRLEPAERRIIEERMQANIARRSGTQRVTYPNAGSFFKNPSGRHAWELIDRA
CCEEECCEEEECHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHC
GMRGVTVGGAQVSEAHTNFLVNRGGACAADFTSLAALVKLRVKETSGVDLEEEVRLVGEE
CCCEEEECCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
TRGELEQAVQGVRGTVKWDEPMWQHTSLKVGGPADLYFEPADLPDLHETVEKLLAAKIP
CHHHHHHHHHHHCCCEECCCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHHCCC
YLVLGGGYNLLVRDGGIRGCVISLKKLDTLEMQPGARLEVGAGVTNSTLCRFAAEHCLGG
EEEECCCEEEEEECCCCCEEEEEEHHCCEEECCCCCEEEECCCCCHHHHHHHHHHHHCCH
MEFLSGIPGSFGGALTMNAGAQGGETLQRVETLITLREGKLLVRKAAELEFGYRYLRLLP
HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCC
GEIVLGAKLRLEPAERRIIEERMQANIARRSGTQRVTYPNAGSFFKNPSGRHAWELIDRA
CCEEECCEEEECHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHC
GMRGVTVGGAQVSEAHTNFLVNRGGACAADFTSLAALVKLRVKETSGVDLEEEVRLVGEE
CCCEEEECCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA