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The map label for this gene is xerC [H]

Identifier: 197116868

GI number: 197116868

Start: 567960

End: 568841

Strand: Reverse

Name: xerC [H]

Synonym: Gbem_0470

Alternate gene names: 197116868

Gene position: 568841-567960 (Counterclockwise)

Preceding gene: 197116874

Following gene: 197116864

Centisome position: 12.33

GC content: 66.33

Gene sequence:

>882_bases
ATGAAAGCCGAACTGGAGCAATTCTATAGCTACCTGGAGACCGAGCGCAACGTCTCCCCCCACACGCTCGCCGCCTACCG
AAGCGACCTGGAGCAGTTCCTCTCGTTCCTGGCCAGGGAGCGGGAGGCGCCGCGCGCAGAAGAGGTGGACCACTTGGCCA
TCAGACGCTACCTGGCGCAGCTGCACAAGGGATGCGCCAAGAGCTCCATCGGCCGCAAGCTTTCCGCCATCAGGGCGCTT
TTTCGGTACCTTATGCGCGAGGGGAAGCTGGAGAAAAATCCGGCCGAGCTGGTGAGCACCCCGAAAAAGGAGAAACGGCT
CCCGTTCCATCTCAACATCGACCAGGTCAGCGCGCTGGTGACAGCGCCCGCCGGCAGCTCCGGGCTGCCGCTTCGGGACC
GCGCCGTCCTGGAGACGCTCTACTCCTGCGGCATCAGGGTGAGCGAGCTGACCGGCATGAACGTGGGCGACATGGATCTC
GCAGCGGGCCTTGCGCGGGTCATGGGCAAAGGGGGGAAAGAGCGGCTGGTCCCGGTGGGATCCTGCGCCAGAAGCGCCCT
TGCCGCCTATCTCGCCGAGCGCGCGGACCCGGGGCCTGCCGAGCCGCTGATCCTGAACGCCCGGGGGGGGCGGCTCACCC
GGCGCAGCGTGGCGCGCATCGTCGACGCTCACATGCTCCTGATCGCCGCCATGCGCAAGGTCTCCCCGCACACCCTGCGC
CACACCTTTGCCACCCATCTGCTGGAAGGAGGCGCCGACCTGCGCGCCATCCAGGAGCTACTGGGGCACGCCTCGCTCTC
TACCACCCAGAAATACACCCACGTCAGCATCGACAAGCTGATGGAGGTCTACGACAAGGCCCACCCCAAGGCGCGCGAGT
AA

Upstream 100 bases:

>100_bases
CTCCCGCCGGTAATCACCCACCTTCTCTACGGCAACCTGGTACATGCCCCCTCCGGAAATTCGTTGTCAAGCGGCGCCTT
CATGAGTAAGATTCCATACC

Downstream 100 bases:

>100_bases
TCCCACACCACTTGTGCGGTTAATCCACTTTAATTCTATATATTTAAGTAAACAGAGCCTTGCACAGCGGCGCAATACGT
TGTAAGTTGGACGGCGCACG

Product: site-specific recombinase, XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKAELEQFYSYLETERNVSPHTLAAYRSDLEQFLSFLAREREAPRAEEVDHLAIRRYLAQLHKGCAKSSIGRKLSAIRAL
FRYLMREGKLEKNPAELVSTPKKEKRLPFHLNIDQVSALVTAPAGSSGLPLRDRAVLETLYSCGIRVSELTGMNVGDMDL
AAGLARVMGKGGKERLVPVGSCARSALAAYLAERADPGPAEPLILNARGGRLTRRSVARIVDAHMLLIAAMRKVSPHTLR
HTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVSIDKLMEVYDKAHPKARE

Sequences:

>Translated_293_residues
MKAELEQFYSYLETERNVSPHTLAAYRSDLEQFLSFLAREREAPRAEEVDHLAIRRYLAQLHKGCAKSSIGRKLSAIRAL
FRYLMREGKLEKNPAELVSTPKKEKRLPFHLNIDQVSALVTAPAGSSGLPLRDRAVLETLYSCGIRVSELTGMNVGDMDL
AAGLARVMGKGGKERLVPVGSCARSALAAYLAERADPGPAEPLILNARGGRLTRRSVARIVDAHMLLIAAMRKVSPHTLR
HTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVSIDKLMEVYDKAHPKARE
>Mature_293_residues
MKAELEQFYSYLETERNVSPHTLAAYRSDLEQFLSFLAREREAPRAEEVDHLAIRRYLAQLHKGCAKSSIGRKLSAIRAL
FRYLMREGKLEKNPAELVSTPKKEKRLPFHLNIDQVSALVTAPAGSSGLPLRDRAVLETLYSCGIRVSELTGMNVGDMDL
AAGLARVMGKGGKERLVPVGSCARSALAAYLAERADPGPAEPLILNARGGRLTRRSVARIVDAHMLLIAAMRKVSPHTLR
HTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVSIDKLMEVYDKAHPKARE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=38.4353741496599, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=42.0875420875421, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1790768, Length=182, Percent_Identity=29.1208791208791, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32384; Mature: 32384

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAELEQFYSYLETERNVSPHTLAAYRSDLEQFLSFLAREREAPRAEEVDHLAIRRYLAQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHKGCAKSSIGRKLSAIRALFRYLMREGKLEKNPAELVSTPKKEKRLPFHLNIDQVSALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCEEECHHHHHHHH
TAPAGSSGLPLRDRAVLETLYSCGIRVSELTGMNVGDMDLAAGLARVMGKGGKERLVPVG
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
SCARSALAAYLAERADPGPAEPLILNARGGRLTRRSVARIVDAHMLLIAAMRKVSPHTLR
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVSIDKLMEVYDKAHPKARE
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKAELEQFYSYLETERNVSPHTLAAYRSDLEQFLSFLAREREAPRAEEVDHLAIRRYLAQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHKGCAKSSIGRKLSAIRALFRYLMREGKLEKNPAELVSTPKKEKRLPFHLNIDQVSALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCEEECHHHHHHHH
TAPAGSSGLPLRDRAVLETLYSCGIRVSELTGMNVGDMDLAAGLARVMGKGGKERLVPVG
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHH
SCARSALAAYLAERADPGPAEPLILNARGGRLTRRSVARIVDAHMLLIAAMRKVSPHTLR
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
HTFATHLLEGGADLRAIQELLGHASLSTTQKYTHVSIDKLMEVYDKAHPKARE
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA