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The map label for this gene is yccK [H]

Identifier: 197116800

GI number: 197116800

Start: 478285

End: 479292

Strand: Reverse

Name: yccK [H]

Synonym: Gbem_0402

Alternate gene names: 197116800

Gene position: 479292-478285 (Counterclockwise)

Preceding gene: 197116801

Following gene: 197116799

Centisome position: 10.39

GC content: 63.0

Gene sequence:

>1008_bases
ATGCAAAAGCGAATACTGGGGAAAAGCGGCCTGGAGGTTTCAGCTCTTGGCCTGGGATGCATGGGAATGAGTTTTTCTTA
CGGGCCGCCCAAGGACAAGCAGGAGATGATCGCGCTGCTCCATGCGGCGGTGGAGCGGGGGATAACCTTCTTCGACACGG
CGGAGGTGTACGGGCCGTACATCAACGAGGAGCTGGTCGGCGAGGCGCTCTCGCCCCTGCGCGACAAGGTGGTGATCGCC
ACCAAGTTCGGCTTCGATATCAATCCCGATAAGGACCCAAGGGGGATGAAGGGGGCACCGGCCTTGAACAGCCGGCCGCA
ACACATCAAGGAGGTCGCCGAAGCGTCGCTCAAGCGCCTCAGAATCGATGCCATAGACCTCTTCTACCAGCACCGCGTCG
ACCCTGATGTGCCGATCGAAGAGGTGGCGGGAGCGGTGAAGGAGCTGATCCAGGAAGGAAAGGTGAAGCATTTCGGCCTC
TCCGAAGCCGGGGTCCAGACCATACGCCGCGCTCACGCCGTTCAGCCGGTCGCCGCCTTGCAGAGCGAGTATTCGCTTTG
GTGGAGGCGCCCTGAGGAGGAGGTGCTGCCGACCCTCGAAGAGCTGGGGATCGGGTTCGTCCCCTACAGCCCGCTCGGCA
AGGGGTTCCTTACCGGAAAGATCGATGCGTCCACCACCTTCGACAGCACCGACTTCCGCACCACCCTACCCCGCTTCACG
CCTGAGGCGAGGCAGGCAAACCAGGCCCTGGTCGACCTCATCGGGCAGATCGCGGCGCGCAAGCAGGCGACTCCGGCGCA
GATTGCCTTAGCCTGGCTCCTGGCGCAGAAGCCGTGGATCGTCCCCATCCCGGGAACGACGAAACTGGAGCGCCTGGAGG
AGAACATCGGCGCAGTGAAACTGGAACTGAGCCCCGGCGACCTCGCCGAAATCGGCAGCGCCGCCTCCAAGATCCAGGTG
GAGGGTGCCCGTTACCCGGAAAGGCTGGAAGAATTGACCGGCCGTTAA

Upstream 100 bases:

>100_bases
TCGTACTGTACAATTGGCGGATGCAAATTTTGCAGATGCAGGCAGAACGATCTCAAGGTGTGGACGATTCGACATTCAGC
GAACCCAAAAGGAGAATAGA

Downstream 100 bases:

>100_bases
CACGCAGGAAACAACACTAAAGGAGGAATATCAAATGCCCAACGCCAAAGCCTACTCCGCTGCCAGCGCCACTTCGCCGC
TGGCTTCCACCACCATATCC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQKRILGKSGLEVSALGLGCMGMSFSYGPPKDKQEMIALLHAAVERGITFFDTAEVYGPYINEELVGEALSPLRDKVVIA
TKFGFDINPDKDPRGMKGAPALNSRPQHIKEVAEASLKRLRIDAIDLFYQHRVDPDVPIEEVAGAVKELIQEGKVKHFGL
SEAGVQTIRRAHAVQPVAALQSEYSLWWRRPEEEVLPTLEELGIGFVPYSPLGKGFLTGKIDASTTFDSTDFRTTLPRFT
PEARQANQALVDLIGQIAARKQATPAQIALAWLLAQKPWIVPIPGTTKLERLEENIGAVKLELSPGDLAEIGSAASKIQV
EGARYPERLEELTGR

Sequences:

>Translated_335_residues
MQKRILGKSGLEVSALGLGCMGMSFSYGPPKDKQEMIALLHAAVERGITFFDTAEVYGPYINEELVGEALSPLRDKVVIA
TKFGFDINPDKDPRGMKGAPALNSRPQHIKEVAEASLKRLRIDAIDLFYQHRVDPDVPIEEVAGAVKELIQEGKVKHFGL
SEAGVQTIRRAHAVQPVAALQSEYSLWWRRPEEEVLPTLEELGIGFVPYSPLGKGFLTGKIDASTTFDSTDFRTTLPRFT
PEARQANQALVDLIGQIAARKQATPAQIALAWLLAQKPWIVPIPGTTKLERLEENIGAVKLELSPGDLAEIGSAASKIQV
EGARYPERLEELTGR
>Mature_335_residues
MQKRILGKSGLEVSALGLGCMGMSFSYGPPKDKQEMIALLHAAVERGITFFDTAEVYGPYINEELVGEALSPLRDKVVIA
TKFGFDINPDKDPRGMKGAPALNSRPQHIKEVAEASLKRLRIDAIDLFYQHRVDPDVPIEEVAGAVKELIQEGKVKHFGL
SEAGVQTIRRAHAVQPVAALQSEYSLWWRRPEEEVLPTLEELGIGFVPYSPLGKGFLTGKIDASTTFDSTDFRTTLPRFT
PEARQANQALVDLIGQIAARKQATPAQIALAWLLAQKPWIVPIPGTTKLERLEENIGAVKLELSPGDLAEIGSAASKIQV
EGARYPERLEELTGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=31.0030395136778, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI4504825, Length=326, Percent_Identity=30.9815950920245, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=30.5810397553517, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436964, Length=319, Percent_Identity=31.3479623824451, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI27436966, Length=319, Percent_Identity=31.3479623824451, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI27436962, Length=315, Percent_Identity=30.4761904761905, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI223718702, Length=312, Percent_Identity=29.8076923076923, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=30.6049822064057, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI41152114, Length=312, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=32.1212121212121, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789375, Length=332, Percent_Identity=32.2289156626506, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787674, Length=301, Percent_Identity=29.5681063122924, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=32.4159021406728, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788081, Length=318, Percent_Identity=27.3584905660377, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994888, Length=293, Percent_Identity=26.962457337884, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=317, Percent_Identity=24.2902208201893, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=27.4096385542169, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=316, Percent_Identity=28.1645569620253, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=351, Percent_Identity=27.9202279202279, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=287, Percent_Identity=27.5261324041812, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=25.776397515528, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=241, Percent_Identity=26.5560165975104, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=157, Percent_Identity=34.3949044585987, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640980, Length=332, Percent_Identity=27.4096385542169, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI45549126, Length=332, Percent_Identity=27.4096385542169, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646155, Length=175, Percent_Identity=32, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646159, Length=228, Percent_Identity=28.5087719298246, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36758; Mature: 36758

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRILGKSGLEVSALGLGCMGMSFSYGPPKDKQEMIALLHAAVERGITFFDTAEVYGPY
CCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALSPLRDKVVIATKFGFDINPDKDPRGMKGAPALNSRPQHIKEVAEASLKRL
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RIDAIDLFYQHRVDPDVPIEEVAGAVKELIQEGKVKHFGLSEAGVQTIRRAHAVQPVAAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QSEYSLWWRRPEEEVLPTLEELGIGFVPYSPLGKGFLTGKIDASTTFDSTDFRTTLPRFT
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCC
PEARQANQALVDLIGQIAARKQATPAQIALAWLLAQKPWIVPIPGTTKLERLEENIGAVK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEE
LELSPGDLAEIGSAASKIQVEGARYPERLEELTGR
EEECCCCHHHHCCHHHEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MQKRILGKSGLEVSALGLGCMGMSFSYGPPKDKQEMIALLHAAVERGITFFDTAEVYGPY
CCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALSPLRDKVVIATKFGFDINPDKDPRGMKGAPALNSRPQHIKEVAEASLKRL
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RIDAIDLFYQHRVDPDVPIEEVAGAVKELIQEGKVKHFGLSEAGVQTIRRAHAVQPVAAL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QSEYSLWWRRPEEEVLPTLEELGIGFVPYSPLGKGFLTGKIDASTTFDSTDFRTTLPRFT
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCC
PEARQANQALVDLIGQIAARKQATPAQIALAWLLAQKPWIVPIPGTTKLERLEENIGAVK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEE
LELSPGDLAEIGSAASKIQVEGARYPERLEELTGR
EEECCCCHHHHCCHHHEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]