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The map label for this gene is luxQ [H]

Identifier: 197116777

GI number: 197116777

Start: 454465

End: 456408

Strand: Reverse

Name: luxQ [H]

Synonym: Gbem_0379

Alternate gene names: 197116777

Gene position: 456408-454465 (Counterclockwise)

Preceding gene: 197116778

Following gene: 197116776

Centisome position: 9.89

GC content: 60.29

Gene sequence:

>1944_bases
ATGGACGAAAGCCGCGACAACCATAGCTTCGCCTTTTTGGAGCAGAAGGTCGAGGAGCGAACCCGCGAGTTGAAACAGGA
GATCCAGGAGCGCCTGCGCGCCGAAGGGCAACTGGCCGAGGCGCGGGACCACTACCTGAACATCCTGGCCGAGGCCCCCG
CTCTGATCTGGCGTGCCGACACGCAGGCCAAGTGCGACTGGTTCAACCACACCTGGCTTTCTTTCACCGGCCGCACCATG
GAAGAGGAATACGGCGACGGCTGGGCACAGGGGGTCCACCCCGACGACCTGGAGCGCTGCGTTGCCATCTGGCTTGGGGC
GTTTCACCAGAAGGCCCCGTTCGAAATGGAGTACCGGCTGCGACGCCACGACGGCGTATTCCGCTGGATCCTGGACATCG
GCCGGCCCTTCTCCGGGCTCGACGGCAGCTTCGCCGGGTATATCGGTTACTGCTTCGACATCACCGACCGCAAGGGTGCG
GAGATGGAGCTGGTATTGGCAAGAGAAGCCGCCGAGGCTGCCAGTAAAGCGAAGACCGAGTTCCTGGCCAACATGAGCCA
CGAGATCCGCACCCCGATGAACAGCATCATCGGGATGACGCAGCTTCTGGCCTACACTGAGCTTTCAGCCGAGCAGAAGG
AGTACGTCGAGGGAATCCTCACCTCTTCGGAGGGTCTCCTTGCTATCATCAACGACATCCTCGATCTTTCGAAAGTGGAG
GCGGGGAAGATCGAACTGGAGTCGCGGAATTTCAGCCTCAGGCAGAGCATCAACGAAATCATCAGGACCCAGACGGCGGC
GGCCCACGAAAAGGGGCTCCAGCTGAAAGTCAGTATCCCTGAAGAGATCCCCGATGCGGTGGTCGGCGACCGGCTAAGGC
TAAAGCAGGTGCTACTCAACATCATCGGCAACGCGATCAAGTTCACCGCAAGCGGGAGCATTGCGGTAACGGTAGCGCTG
GCGGAAAAAAAAGAGGAAGCGGCCCGCATCACATTCAGCGTCACCGATACCGGCATCGGGATAGCGCCGGAGTCCCTGGA
CCGCATCTTCGCCCCGTTCGCGCAGGAAGACACCTCCACCACCCGGAGGTACGGCGGCACCGGTCTTGGGCTTTCCATCA
GCACGAAGCTGGTCCGGCTCATGGGGGGACGGATCTGGGCGGAAAGCCGCAAGAACGCCGGCAGCACCTTCCACTTTGAG
ATCCCCTTCCGGCTCTGCGCCAAAAAGGCCCGCCCCAAGGCGTCCCTCAATACCGCCAAGAAAGCCGTCTGGGACGGGGC
CAAGCTCCGCATCCTGCTGGCCGACGACCAGGAGATGAACCGCAACATTATGGAGAAACTCCTGGGGCGACTGGGGCACG
ATCTGGAAAGTGCGGCGGATGGCGGCGAGGCGCTAGGAAAATGGGAAAAGGGGAACTTCGACCTCATCCTCATGGATGTC
GAGATGCCCGGTATCGACGGCACGGAAGCGACCCGCGTGATCCGAGAGACCGAGACCCCGCTGGGAAAGCGGACCCCCAT
CATCGCCCTCACCGCCCATGCGCTTAAGAGCCACCAGGAGATGCTTCTCGGACTAGGCTACGACGGGTACGTACCCAAGC
CTGTGGAGATTCCCACGCTGTTGCAGGAGATGAAGCGCTGTCTGCACCTGCCCGACCTTGACACAGCAGGCAACGGCGAC
GCCGCCGACGGAGTTCCCATGACTCCCGCGGCAAACCAGCTTGGCACAGTGGACAGGCAGCAGCTTGCGGATATACTCAC
TGCAGTCAGCTCACTGTTGCGTCAAAGAAACATGAAGGTCATAGACAAGGTAAATGACCTCTCCGCACTGATTCCCGGTT
CACCTCTTCTAGAACAGCTGAACCAGCAGATACGGCAATTCGATTGCCAAAGCGCTCTTAATACAGTCGGACAAATCCTC
CTGAATTACGACATCCACTCCTGA

Upstream 100 bases:

>100_bases
ATGGCAATTTGCTTATAATGTCGCCCAGCTAAGCAACTCCTGCAACACCTATGTTTTTTAGCAACCATAGCGTACGCCGT
TTTCCAGGAGAGCAGCGAGT

Downstream 100 bases:

>100_bases
TGCAGTTTCTGTGCATTGCCACAGAGAAATGAGGATACCGTGGTCAAGAAAAAGCTGCTGGTTGTCGACGACACGCCGGA
AAACCTGATCATTCTCTACA

Product: PAS/PAC domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MDESRDNHSFAFLEQKVEERTRELKQEIQERLRAEGQLAEARDHYLNILAEAPALIWRADTQAKCDWFNHTWLSFTGRTM
EEEYGDGWAQGVHPDDLERCVAIWLGAFHQKAPFEMEYRLRRHDGVFRWILDIGRPFSGLDGSFAGYIGYCFDITDRKGA
EMELVLAREAAEAASKAKTEFLANMSHEIRTPMNSIIGMTQLLAYTELSAEQKEYVEGILTSSEGLLAIINDILDLSKVE
AGKIELESRNFSLRQSINEIIRTQTAAAHEKGLQLKVSIPEEIPDAVVGDRLRLKQVLLNIIGNAIKFTASGSIAVTVAL
AEKKEEAARITFSVTDTGIGIAPESLDRIFAPFAQEDTSTTRRYGGTGLGLSISTKLVRLMGGRIWAESRKNAGSTFHFE
IPFRLCAKKARPKASLNTAKKAVWDGAKLRILLADDQEMNRNIMEKLLGRLGHDLESAADGGEALGKWEKGNFDLILMDV
EMPGIDGTEATRVIRETETPLGKRTPIIALTAHALKSHQEMLLGLGYDGYVPKPVEIPTLLQEMKRCLHLPDLDTAGNGD
AADGVPMTPAANQLGTVDRQQLADILTAVSSLLRQRNMKVIDKVNDLSALIPGSPLLEQLNQQIRQFDCQSALNTVGQIL
LNYDIHS

Sequences:

>Translated_647_residues
MDESRDNHSFAFLEQKVEERTRELKQEIQERLRAEGQLAEARDHYLNILAEAPALIWRADTQAKCDWFNHTWLSFTGRTM
EEEYGDGWAQGVHPDDLERCVAIWLGAFHQKAPFEMEYRLRRHDGVFRWILDIGRPFSGLDGSFAGYIGYCFDITDRKGA
EMELVLAREAAEAASKAKTEFLANMSHEIRTPMNSIIGMTQLLAYTELSAEQKEYVEGILTSSEGLLAIINDILDLSKVE
AGKIELESRNFSLRQSINEIIRTQTAAAHEKGLQLKVSIPEEIPDAVVGDRLRLKQVLLNIIGNAIKFTASGSIAVTVAL
AEKKEEAARITFSVTDTGIGIAPESLDRIFAPFAQEDTSTTRRYGGTGLGLSISTKLVRLMGGRIWAESRKNAGSTFHFE
IPFRLCAKKARPKASLNTAKKAVWDGAKLRILLADDQEMNRNIMEKLLGRLGHDLESAADGGEALGKWEKGNFDLILMDV
EMPGIDGTEATRVIRETETPLGKRTPIIALTAHALKSHQEMLLGLGYDGYVPKPVEIPTLLQEMKRCLHLPDLDTAGNGD
AADGVPMTPAANQLGTVDRQQLADILTAVSSLLRQRNMKVIDKVNDLSALIPGSPLLEQLNQQIRQFDCQSALNTVGQIL
LNYDIHS
>Mature_647_residues
MDESRDNHSFAFLEQKVEERTRELKQEIQERLRAEGQLAEARDHYLNILAEAPALIWRADTQAKCDWFNHTWLSFTGRTM
EEEYGDGWAQGVHPDDLERCVAIWLGAFHQKAPFEMEYRLRRHDGVFRWILDIGRPFSGLDGSFAGYIGYCFDITDRKGA
EMELVLAREAAEAASKAKTEFLANMSHEIRTPMNSIIGMTQLLAYTELSAEQKEYVEGILTSSEGLLAIINDILDLSKVE
AGKIELESRNFSLRQSINEIIRTQTAAAHEKGLQLKVSIPEEIPDAVVGDRLRLKQVLLNIIGNAIKFTASGSIAVTVAL
AEKKEEAARITFSVTDTGIGIAPESLDRIFAPFAQEDTSTTRRYGGTGLGLSISTKLVRLMGGRIWAESRKNAGSTFHFE
IPFRLCAKKARPKASLNTAKKAVWDGAKLRILLADDQEMNRNIMEKLLGRLGHDLESAADGGEALGKWEKGNFDLILMDV
EMPGIDGTEATRVIRETETPLGKRTPIIALTAHALKSHQEMLLGLGYDGYVPKPVEIPTLLQEMKRCLHLPDLDTAGNGD
AADGVPMTPAANQLGTVDRQQLADILTAVSSLLRQRNMKVIDKVNDLSALIPGSPLLEQLNQQIRQFDCQSALNTVGQIL
LNYDIHS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=543, Percent_Identity=30.2025782688766, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=47.9508196721311, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI1788713, Length=431, Percent_Identity=33.6426914153132, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87081816, Length=414, Percent_Identity=32.6086956521739, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=39.453125, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=31.140350877193, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=29.6442687747036, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=31.1965811965812, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=28.2786885245902, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=27.4436090225564, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=25.6, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=26.8722466960352, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788545, Length=152, Percent_Identity=30.2631578947368, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=25.8928571428571, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789808, Length=202, Percent_Identity=30.6930693069307, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=158, Percent_Identity=32.2784810126582, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71849; Mature: 71849

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESRDNHSFAFLEQKVEERTRELKQEIQERLRAEGQLAEARDHYLNILAEAPALIWRAD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECC
TQAKCDWFNHTWLSFTGRTMEEEYGDGWAQGVHPDDLERCVAIWLGAFHQKAPFEMEYRL
CCCCCCCCCCCEEEECCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
RRHDGVFRWILDIGRPFSGLDGSFAGYIGYCFDITDRKGAEMELVLAREAAEAASKAKTE
HHHCCHHHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHH
FLANMSHEIRTPMNSIIGMTQLLAYTELSAEQKEYVEGILTSSEGLLAIINDILDLSKVE
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
AGKIELESRNFSLRQSINEIIRTQTAAAHEKGLQLKVSIPEEIPDAVVGDRLRLKQVLLN
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCHHHHCCHHHHHHHHHH
IIGNAIKFTASGSIAVTVALAEKKEEAARITFSVTDTGIGIAPESLDRIFAPFAQEDTST
HHCCCEEEEECCCEEEEEEEHHCCCCCEEEEEEEECCCCCCCHHHHHHHHCCHHCCCCHH
TRRYGGTGLGLSISTKLVRLMGGRIWAESRKNAGSTFHFEIPFRLCAKKARPKASLNTAK
HHHCCCCCCCHHHHHHHHHHHCCHHEECCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHH
KAVWDGAKLRILLADDQEMNRNIMEKLLGRLGHDLESAADGGEALGKWEKGNFDLILMDV
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCCEEEEEEEE
EMPGIDGTEATRVIRETETPLGKRTPIIALTAHALKSHQEMLLGLGYDGYVPKPVEIPTL
ECCCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LQEMKRCLHLPDLDTAGNGDAADGVPMTPAANQLGTVDRQQLADILTAVSSLLRQRNMKV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IDKVNDLSALIPGSPLLEQLNQQIRQFDCQSALNTVGQILLNYDIHS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDESRDNHSFAFLEQKVEERTRELKQEIQERLRAEGQLAEARDHYLNILAEAPALIWRAD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECC
TQAKCDWFNHTWLSFTGRTMEEEYGDGWAQGVHPDDLERCVAIWLGAFHQKAPFEMEYRL
CCCCCCCCCCCEEEECCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
RRHDGVFRWILDIGRPFSGLDGSFAGYIGYCFDITDRKGAEMELVLAREAAEAASKAKTE
HHHCCHHHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHH
FLANMSHEIRTPMNSIIGMTQLLAYTELSAEQKEYVEGILTSSEGLLAIINDILDLSKVE
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
AGKIELESRNFSLRQSINEIIRTQTAAAHEKGLQLKVSIPEEIPDAVVGDRLRLKQVLLN
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCHHHHCCHHHHHHHHHH
IIGNAIKFTASGSIAVTVALAEKKEEAARITFSVTDTGIGIAPESLDRIFAPFAQEDTST
HHCCCEEEEECCCEEEEEEEHHCCCCCEEEEEEEECCCCCCCHHHHHHHHCCHHCCCCHH
TRRYGGTGLGLSISTKLVRLMGGRIWAESRKNAGSTFHFEIPFRLCAKKARPKASLNTAK
HHHCCCCCCCHHHHHHHHHHHCCHHEECCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHH
KAVWDGAKLRILLADDQEMNRNIMEKLLGRLGHDLESAADGGEALGKWEKGNFDLILMDV
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCCEEEEEEEE
EMPGIDGTEATRVIRETETPLGKRTPIIALTAHALKSHQEMLLGLGYDGYVPKPVEIPTL
ECCCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LQEMKRCLHLPDLDTAGNGDAADGVPMTPAANQLGTVDRQQLADILTAVSSLLRQRNMKV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
IDKVNDLSALIPGSPLLEQLNQQIRQFDCQSALNTVGQILLNYDIHS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA