Click here to switch to the map view.

The map label for this gene is 197116734

Identifier: 197116734

GI number: 197116734

Start: 409936

End: 411441

Strand: Direct

Name: 197116734

Synonym: Gbem_0334

Alternate gene names: NA

Gene position: 409936-411441 (Clockwise)

Preceding gene: 197116733

Following gene: 197116735

Centisome position: 8.88

GC content: 63.01

Gene sequence:

>1506_bases
ATGGACCGCATTATCGACATAACCGAACTGGCTCTGCGCGACGCGCACCAGAGCCTTATCGCTACGAGGCTCGGGATAGA
CGACATGGTTCCGGTGTGCGAGGACCTGGACCAGGCGGGCTACTGGTCCATCGAGTGCTGGGGCGGGGCCACCTATGACG
CCTGCATCCGCTTTCTCAACGAAGATCCGTGGGTGAGGCTTAGGACCTTCAAGGAGCTGATGCCGAAAACCCCGCTGCAG
ATGCTTTTGCGGGGGCAGAACCTTTTGGGATACCGGCATTACCAGGACGAGGTGGTGGACCGGTTCGTCCAGAAGAGCGC
CGAGAACGGCATCGACGTGTTCCGGATCTTCGATGCGCTGAACGATCTGAGGAACCTGGAGCGGTCGGTCCAGGCGGTGA
AGCAGTGCGGAAAGCACGCGCAGGTCGCCATCTCCTATACCATCAGCCCCATTCACACCACGGCGAAATTCGTGGAGCAG
GCGAAGCGCCTGGTCGACATGGGGTGCGACTCCATCTGCATCAAGGACATGGCGGCGCTGATCAAGCCGCACGCGACATA
CGACCTGGTGAGAGGGATCAAAGAGGCCTGCGGCGACCGGATCCGGATACAGCTGCATGCGCACGCCACCAGCGGCGTGA
CCATGGTGAGTTACATGAAGGCGGTGGAGGCGGGCGTGGACGGCGTGGACACGGCGGTGAGTTCCATGAGCCTCGGGCCC
GGACACAACCCGACGGAGAGCTTTGCGGAGATGCTGGAAAATACGGGCTACACCACGCGCATCGACCTCGGCCGGGTGAA
CAAGGTGAAGGAGCATTTCGCCAAGGTGCTCCCCAGGTACTCAGAATTCCTCTCCACCATCACCGGCGCGGAGACGGAGA
TCTTCAGGAGCCAGATTCCAGGCGGGATGCTTTCCAACATGGAGAGCCAGTTGAAGCAGCAGGGGGCTGGGGACCGGATG
CGCGACGTGCTGGAAGAGATACCGCTGGTGAGAAAGGACACGGGATACGTCCCGCTGGTAACCCCGACCAGCCAGATCGT
CGGGACCCAGGCGGTGCTGAACGTATTGATGGGGCGCTACAAGGTGCTGACCGGCGAGTTCGCCGACCTGATGCTCGGCT
ACTACGGCCTCACGCCGGGAGAACGGAACCCGGAGGTGGTGGAGCAGGCGCGCCGCCACGCGAATAAGGAGCCGATAGAG
TGCCGCCCCGCAGATCTATTGGAGCCGGAATGGGGCAAGCTGCGGGCGGCGGCGCTCCCCTTGGAGGGTTGCGACGGCAG
CGACGAGGACGTGCTCACCTACGCCCTCTTTCCGCAGGTGGCGCCGAAGTTCTTCGCCACGAGGAGTGAAGGACCCCGAA
ACCTGGGGCGCGATCCCGTCACCGGAGCTTCGGAAACCAGCATTCCCGAAGGGCACCCCGGGAAGATCACCGGCCCCGTC
ACCTACACGGTCACCTTGAGCGGGCAGCCGCACAAGGTGACGGTTGCACCCTACGGCCAGGAATAG

Upstream 100 bases:

>100_bases
GCGAAAGATGGTGCCAATCCATTTTTAAAAAAAAGAGTATTAGCTCTTGTCAATGAGCTTGCAGTCCGTAGAATATCCCT
TCGTGACTAAGGAGGGAGAC

Downstream 100 bases:

>100_bases
GCGCCGCACCGACCAAGGAGCGAGCTCATGTCCATAGAAGAGAAGATAAAAGCGCTGAACGACAAGAAGAGCAAGCTGAA
GCTGGGCGGCGGGCGCTCGA

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: Transcarboxylase 5S subunit [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MDRIIDITELALRDAHQSLIATRLGIDDMVPVCEDLDQAGYWSIECWGGATYDACIRFLNEDPWVRLRTFKELMPKTPLQ
MLLRGQNLLGYRHYQDEVVDRFVQKSAENGIDVFRIFDALNDLRNLERSVQAVKQCGKHAQVAISYTISPIHTTAKFVEQ
AKRLVDMGCDSICIKDMAALIKPHATYDLVRGIKEACGDRIRIQLHAHATSGVTMVSYMKAVEAGVDGVDTAVSSMSLGP
GHNPTESFAEMLENTGYTTRIDLGRVNKVKEHFAKVLPRYSEFLSTITGAETEIFRSQIPGGMLSNMESQLKQQGAGDRM
RDVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRYKVLTGEFADLMLGYYGLTPGERNPEVVEQARRHANKEPIE
CRPADLLEPEWGKLRAAALPLEGCDGSDEDVLTYALFPQVAPKFFATRSEGPRNLGRDPVTGASETSIPEGHPGKITGPV
TYTVTLSGQPHKVTVAPYGQE

Sequences:

>Translated_501_residues
MDRIIDITELALRDAHQSLIATRLGIDDMVPVCEDLDQAGYWSIECWGGATYDACIRFLNEDPWVRLRTFKELMPKTPLQ
MLLRGQNLLGYRHYQDEVVDRFVQKSAENGIDVFRIFDALNDLRNLERSVQAVKQCGKHAQVAISYTISPIHTTAKFVEQ
AKRLVDMGCDSICIKDMAALIKPHATYDLVRGIKEACGDRIRIQLHAHATSGVTMVSYMKAVEAGVDGVDTAVSSMSLGP
GHNPTESFAEMLENTGYTTRIDLGRVNKVKEHFAKVLPRYSEFLSTITGAETEIFRSQIPGGMLSNMESQLKQQGAGDRM
RDVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRYKVLTGEFADLMLGYYGLTPGERNPEVVEQARRHANKEPIE
CRPADLLEPEWGKLRAAALPLEGCDGSDEDVLTYALFPQVAPKFFATRSEGPRNLGRDPVTGASETSIPEGHPGKITGPV
TYTVTLSGQPHKVTVAPYGQE
>Mature_501_residues
MDRIIDITELALRDAHQSLIATRLGIDDMVPVCEDLDQAGYWSIECWGGATYDACIRFLNEDPWVRLRTFKELMPKTPLQ
MLLRGQNLLGYRHYQDEVVDRFVQKSAENGIDVFRIFDALNDLRNLERSVQAVKQCGKHAQVAISYTISPIHTTAKFVEQ
AKRLVDMGCDSICIKDMAALIKPHATYDLVRGIKEACGDRIRIQLHAHATSGVTMVSYMKAVEAGVDGVDTAVSSMSLGP
GHNPTESFAEMLENTGYTTRIDLGRVNKVKEHFAKVLPRYSEFLSTITGAETEIFRSQIPGGMLSNMESQLKQQGAGDRM
RDVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRYKVLTGEFADLMLGYYGLTPGERNPEVVEQARRHANKEPIE
CRPADLLEPEWGKLRAAALPLEGCDGSDEDVLTYALFPQVAPKFFATRSEGPRNLGRDPVTGASETSIPEGHPGKITGPV
TYTVTLSGQPHKVTVAPYGQE

Specific function: The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=459, Percent_Identity=32.0261437908497, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI106049295, Length=459, Percent_Identity=32.0261437908497, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI106049292, Length=459, Percent_Identity=32.0261437908497, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17562816, Length=474, Percent_Identity=33.7552742616034, Blast_Score=230, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6319695, Length=458, Percent_Identity=33.4061135371179, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6321376, Length=458, Percent_Identity=33.4061135371179, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24652212, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652210, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652214, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI19921944, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652216, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI281363050, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652224, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652222, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652220, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652218, Length=468, Percent_Identity=32.9059829059829, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003379
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 55427; Mature: 55427

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIIDITELALRDAHQSLIATRLGIDDMVPVCEDLDQAGYWSIECWGGATYDACIRFLN
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHC
EDPWVRLRTFKELMPKTPLQMLLRGQNLLGYRHYQDEVVDRFVQKSAENGIDVFRIFDAL
CCCCCHHHHHHHHCCCCHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NDLRNLERSVQAVKQCGKHAQVAISYTISPIHTTAKFVEQAKRLVDMGCDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKPHATYDLVRGIKEACGDRIRIQLHAHATSGVTMVSYMKAVEAGVDGVDTAVSSMSLGP
HCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
GHNPTESFAEMLENTGYTTRIDLGRVNKVKEHFAKVLPRYSEFLSTITGAETEIFRSQIP
CCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGMLSNMESQLKQQGAGDRMRDVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRY
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHH
KVLTGEFADLMLGYYGLTPGERNPEVVEQARRHANKEPIECRPADLLEPEWGKLRAAALP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCC
LEGCDGSDEDVLTYALFPQVAPKFFATRSEGPRNLGRDPVTGASETSIPEGHPGKITGPV
CCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCE
TYTVTLSGQPHKVTVAPYGQE
EEEEEECCCCCEEEECCCCCC
>Mature Secondary Structure
MDRIIDITELALRDAHQSLIATRLGIDDMVPVCEDLDQAGYWSIECWGGATYDACIRFLN
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHC
EDPWVRLRTFKELMPKTPLQMLLRGQNLLGYRHYQDEVVDRFVQKSAENGIDVFRIFDAL
CCCCCHHHHHHHHCCCCHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NDLRNLERSVQAVKQCGKHAQVAISYTISPIHTTAKFVEQAKRLVDMGCDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKPHATYDLVRGIKEACGDRIRIQLHAHATSGVTMVSYMKAVEAGVDGVDTAVSSMSLGP
HCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCC
GHNPTESFAEMLENTGYTTRIDLGRVNKVKEHFAKVLPRYSEFLSTITGAETEIFRSQIP
CCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGMLSNMESQLKQQGAGDRMRDVLEEIPLVRKDTGYVPLVTPTSQIVGTQAVLNVLMGRY
CHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHH
KVLTGEFADLMLGYYGLTPGERNPEVVEQARRHANKEPIECRPADLLEPEWGKLRAAALP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCC
LEGCDGSDEDVLTYALFPQVAPKFFATRSEGPRNLGRDPVTGASETSIPEGHPGKITGPV
CCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCE
TYTVTLSGQPHKVTVAPYGQE
EEEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365490 [H]