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The map label for this gene is crp [C]

Identifier: 197104177

GI number: 197104177

Start: 780012

End: 780707

Strand: Direct

Name: crp [C]

Synonym: PHZ_c0711

Alternate gene names: 197104177

Gene position: 780012-780707 (Clockwise)

Preceding gene: 197104170

Following gene: 197104179

Centisome position: 19.52

GC content: 76.72

Gene sequence:

>696_bases
ATGGCCATTGGAGAGGGTGAGCCGCTGGAGCGGATCGCCGCGGCGCTGGCGCGCGGCGAGGTGTTGGGCCTGCTCCCGGA
AGAGGCCCGGCGGCGGCTGGCCCGGACCGGCGCGCCCGTCGATCTCATCCCCGGCGAGTTGCTCTGCCAAGCCGGCGATC
CCGGCGATGCGGTCTATGTGATCCTCGACGGCGAACTGGAGGTCCGGCGCCTTTCGGCCGCCGGCCGCGAGCTGCGGCTC
GTGGCCCTTGGCCCCGGCGCGCTGGCGGGCGAGATGGCGGTGCTGGACGGGGGCGCGCGCTCGGCGGACATCGTCGCCAG
CCGGCGCGCGCATCTGTGGCGCGTGCCCCGCCAGGCCCTGCTGGAGGCGCTGGAGGCCGAGCCCCGCGCGCTGCTCGCGC
TGGTGGCCGAGCTCAGCCGCCGGCTCCGCGCCGTCAACGCCGCCCTCGAGGCGCGCAGCACCCTCGATCTCGGCGGCCGC
CTGGCCGGACTCCTGATGGCCGAACAGACCGGCCGGGGCCTCGTGCCGCTCAGCCAGGGCGAGCTGGCGCGCCGCCTGGG
CGCCTCGCGCGAGAAGGTGAACCGCAAGCTCAGGGAATGGAGCGCCTCCGGCTGGGTGGAGACGACGCCGGCCGGCCTGC
GCATCCTGGGCGAGACGCGGCTGCGCGCGCTCTCGGCGGGTCCGTGGTCGGCCTGA

Upstream 100 bases:

>100_bases
TCCTGCTGGCCCGCCGCGGCCGCTGATCGCCACTCCGCCGGCTCCCGGGCCGTGCTATGATGGCCCGGGAGCTGGGGCCT
TGCCGTTCGTGGAGGCGGGC

Downstream 100 bases:

>100_bases
TCGCGTCCCGAGCACCCAATGTTAAGCGGGGTCGGCGGCAAGCGGCGCCATGATGGACCAGTGCATCCAGGAGCCCGCCC
ATGCCCATGTACGAGGCCTA

Product: transcriptional regulator, Crp/Fnr family

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Catabolite Gene Activator; Cyclic AMP Receptor Protein; CRP Family Transcriptional Regulator; Transcriptional Regulatory Protein Crp Family; Transcriptional Regulator Crp; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAIGEGEPLERIAAALARGEVLGLLPEEARRRLARTGAPVDLIPGELLCQAGDPGDAVYVILDGELEVRRLSAAGRELRL
VALGPGALAGEMAVLDGGARSADIVASRRAHLWRVPRQALLEALEAEPRALLALVAELSRRLRAVNAALEARSTLDLGGR
LAGLLMAEQTGRGLVPLSQGELARRLGASREKVNRKLREWSASGWVETTPAGLRILGETRLRALSAGPWSA

Sequences:

>Translated_231_residues
MAIGEGEPLERIAAALARGEVLGLLPEEARRRLARTGAPVDLIPGELLCQAGDPGDAVYVILDGELEVRRLSAAGRELRL
VALGPGALAGEMAVLDGGARSADIVASRRAHLWRVPRQALLEALEAEPRALLALVAELSRRLRAVNAALEARSTLDLGGR
LAGLLMAEQTGRGLVPLSQGELARRLGASREKVNRKLREWSASGWVETTPAGLRILGETRLRALSAGPWSA
>Mature_230_residues
AIGEGEPLERIAAALARGEVLGLLPEEARRRLARTGAPVDLIPGELLCQAGDPGDAVYVILDGELEVRRLSAAGRELRLV
ALGPGALAGEMAVLDGGARSADIVASRRAHLWRVPRQALLEALEAEPRALLALVAELSRRLRAVNAALEARSTLDLGGRL
AGLLMAEQTGRGLVPLSQGELARRLGASREKVNRKLREWSASGWVETTPAGLRILGETRLRALSAGPWSA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24484; Mature: 24352

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00888 CNMP_BINDING_1 ; PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGEGEPLERIAAALARGEVLGLLPEEARRRLARTGAPVDLIPGELLCQAGDPGDAVYV
CCCCCCCCHHHHHHHHHCCHHEECCCHHHHHHHHHCCCCCEECCHHHEECCCCCCCEEEE
ILDGELEVRRLSAAGRELRLVALGPGALAGEMAVLDGGARSADIVASRRAHLWRVPRQAL
EECCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHH
LEALEAEPRALLALVAELSRRLRAVNAALEARSTLDLGGRLAGLLMAEQTGRGLVPLSQG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ELARRLGASREKVNRKLREWSASGWVETTPAGLRILGETRLRALSAGPWSA
HHHHHHCCCHHHHHHHHHHHCCCCCEEECCCHHEEECHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIGEGEPLERIAAALARGEVLGLLPEEARRRLARTGAPVDLIPGELLCQAGDPGDAVYV
CCCCCCCHHHHHHHHHCCHHEECCCHHHHHHHHHCCCCCEECCHHHEECCCCCCCEEEE
ILDGELEVRRLSAAGRELRLVALGPGALAGEMAVLDGGARSADIVASRRAHLWRVPRQAL
EECCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHH
LEALEAEPRALLALVAELSRRLRAVNAALEARSTLDLGGRLAGLLMAEQTGRGLVPLSQG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ELARRLGASREKVNRKLREWSASGWVETTPAGLRILGETRLRALSAGPWSA
HHHHHHCCCHHHHHHHHHHHCCCCCEEECCCHHEEECHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA