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The map label for this gene is cheA [H]

Identifier: 197104160

GI number: 197104160

Start: 757501

End: 759645

Strand: Direct

Name: cheA [H]

Synonym: PHZ_c0694

Alternate gene names: 197104160

Gene position: 757501-759645 (Clockwise)

Preceding gene: 197104159

Following gene: 197104161

Centisome position: 18.96

GC content: 74.45

Gene sequence:

>2145_bases
TTGGCCGACATCCGCGCCCAGCTGCTGGCCGCCTTCGAGGTCGAGCACCGCGAGCACCTCGAAGCGATCCGTCGCGCCCT
GACCGCGCCGGAGCAGGCCGACCTGCGCGAGGTGTTCCGGCGCGCGCACAGCCTGAAGGGCGCGGCCCGGGCCGTGGACC
TGCCGCGCATCGAGGAGCTGGCGCACGGGCTGGAGGACCTGATCGCGGGGGTGGGCGAGGGAGCCGGCGCGCTCGACCGT
CCGACCCTGGACGCCATCCACCTGCTCCTGGACCGCATCGAGGCCGAGGCCGAGGCGGCGCGTACGGGCGTCCCCCCCGA
CGGTCCGGACCAGGCGCCTTCGGAGGGCGAGCCGCCCGCCGAGGCGGCGGCTTCGGCGGTCGAGGGTGAGGCGGGGCTCG
AGTATGTGCGCATCGACGCCCAGGCGCTCCGCGAGCTGGCCCAGGCCGCGCACCAGCTGGCCAACGACGTGCGGGCCGAA
CAGTCGGCGCCGCAGCAGCTTCGCCGCCTCCACCGCGAGAGCCGCCGGCTCGAGCAGCTGTGGAGCGAGCTGCGCCTGCG
GCTGGGCGAAGGCCGGGACGGGGCGCGGGCGCGCGATTTCGAGCACGCCCTCAAGACGCTGACGCGCGACCTGGCGGACC
TGGGACAGACGCAGCATCGCACGAGCTGGAGCCTGCAGACCGACCTGGGAGTGCTGCGCGAGCAGGTGGACCGCATCGCC
CTGACGCCGGCCGCCACGGTGTTCGGGGACCTGGGCCGGATGGTCCGCGAGCTCGCCCGCGCGGAGGGGGTCGAAGTGGA
CGTCCGCGTCGAGGGCCTGGACGTGCGCGCCGAACGGCGGGTGCTGCAGGCGCTGCGCGATCCCGTCATCCACCTGCTGC
GCAATGCGCTCAGCCACGGCGCGGAGCCTGCCGAGGCGCGCCGGCGGGCCGGCAAGCCCGAGGCGCTGGCGGTGGGCCTG
CAAATCTCGGCGCGGGGCGATCGCCTGCAGGCCAGAGTCTACGACGACGGCGCTGGTCCCGACCTGGCGCGCATCGAGCA
GGCGGCGATCGACCGGGGTTTGCTTCCGAAGCGCAGCCCGGCGACCCCGCCGCCGAGCCCGGAGGAGGTCCTCGCCCTGG
CGTTCGAACCGGGCGTCTCGTCGGCCGAGGCGGTGGACCGCCTGGCGGGACGCGGCATGGGCCTGTCGATCGTGCTGCAG
TCGGTGCGCGGCCTCGGTGGCGGCGCGAGGCTCGGCGCGCGCCGGCCCTACGGCGCCGAAGTGGTCGTCTCGGCGCCGCT
GTCGCTGGCGCGCCAGACCGTGATCCTGATCGAGACGGGCGGCGGGACGTTCGGCCTGCCGAGCTTCGGCGTCGTGCGGC
TGCTGCGCCTGGCGCAGGATCGGCTGGAAACCGTCGAAGGGGCGCTGACGGCCCGGATAGGAATCGGCGAGGCGGACGTT
GTCGTCCCGGTGGTGTCGATGGCGGCGGTCCTGGGAAATGCCGAGTCCGAGATCCCCGCCTCGGGCGGGACGGTGAGCGC
CGTGCTGCTGTCGCGCGGCGAGCGGCACGTGGCCTTCGCGGTCGACGCCTTCTCGGACGTGCGGGAGATGGCGGTGGAGG
CCGCGCCGGGCGAGGGGCTCGATGCGCCGCTGGCCCTCGGCGTGGCCCTGCTGGAAGGCGAGACCCCGCTCATGGTGCTC
GATCCCGACGGGCTGGTGGACCGCTGGCTGCGCGACGAGCGGCGGCTGGCGGCGGCGGGTCTGGGCCTGGCCTCGCGGGC
GGCCGAGCGCCCGCGCCAGCGGACCGTGCTGGTGGTGGACGATTCCATCACCACGCGCACGCTGGAGAAGAGCATCCTGG
AGGGGCAGGGCTACCGCGTGCTGCTGGCGGTCGACGGGGTGGACGCGTTGCACGTCCTTCGCTCGGGCGAGGCGATCGTC
GACGTGGTGGTGGCCGACGTCGAGATGCCGCGCATGGACGGCTTCTCGCTGCTGCAGGCGGTCAAGGCCGACGCCAGCCT
TGCGGCCCTGCCGGTCATCCTGATGACCTCGCGCAACGACCCGACCGACGTGCGGCGGGGCATGGACCTGGGCGCCGAGG
CCTACATCACCAAGCAGAAGTTCGACCAGCGCGAGCTGCTGGCCACCATCGGACGGATCCTGTGA

Upstream 100 bases:

>100_bases
CGCCGGCACGCGCCAGCTGGACGAGGCCGCCGCCAACCTGACGCGCCTCTCGCAACAGCTGCTCGCGCTCGCCGAACGCT
ACCGGCTCTAGGGCCTGGCC

Downstream 100 bases:

>100_bases
AGTCGCCCGAGCGCCCTGTCCGCGTCATGATCGTCGAGGACTCTCTGGTCGTGCGCCAGCTCCTCGCCCACCTGATCGGC
CGCGATCCCCGGTTCGTGGT

Product: Chemotaxis histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MADIRAQLLAAFEVEHREHLEAIRRALTAPEQADLREVFRRAHSLKGAARAVDLPRIEELAHGLEDLIAGVGEGAGALDR
PTLDAIHLLLDRIEAEAEAARTGVPPDGPDQAPSEGEPPAEAAASAVEGEAGLEYVRIDAQALRELAQAAHQLANDVRAE
QSAPQQLRRLHRESRRLEQLWSELRLRLGEGRDGARARDFEHALKTLTRDLADLGQTQHRTSWSLQTDLGVLREQVDRIA
LTPAATVFGDLGRMVRELARAEGVEVDVRVEGLDVRAERRVLQALRDPVIHLLRNALSHGAEPAEARRRAGKPEALAVGL
QISARGDRLQARVYDDGAGPDLARIEQAAIDRGLLPKRSPATPPPSPEEVLALAFEPGVSSAEAVDRLAGRGMGLSIVLQ
SVRGLGGGARLGARRPYGAEVVVSAPLSLARQTVILIETGGGTFGLPSFGVVRLLRLAQDRLETVEGALTARIGIGEADV
VVPVVSMAAVLGNAESEIPASGGTVSAVLLSRGERHVAFAVDAFSDVREMAVEAAPGEGLDAPLALGVALLEGETPLMVL
DPDGLVDRWLRDERRLAAAGLGLASRAAERPRQRTVLVVDDSITTRTLEKSILEGQGYRVLLAVDGVDALHVLRSGEAIV
DVVVADVEMPRMDGFSLLQAVKADASLAALPVILMTSRNDPTDVRRGMDLGAEAYITKQKFDQRELLATIGRIL

Sequences:

>Translated_714_residues
MADIRAQLLAAFEVEHREHLEAIRRALTAPEQADLREVFRRAHSLKGAARAVDLPRIEELAHGLEDLIAGVGEGAGALDR
PTLDAIHLLLDRIEAEAEAARTGVPPDGPDQAPSEGEPPAEAAASAVEGEAGLEYVRIDAQALRELAQAAHQLANDVRAE
QSAPQQLRRLHRESRRLEQLWSELRLRLGEGRDGARARDFEHALKTLTRDLADLGQTQHRTSWSLQTDLGVLREQVDRIA
LTPAATVFGDLGRMVRELARAEGVEVDVRVEGLDVRAERRVLQALRDPVIHLLRNALSHGAEPAEARRRAGKPEALAVGL
QISARGDRLQARVYDDGAGPDLARIEQAAIDRGLLPKRSPATPPPSPEEVLALAFEPGVSSAEAVDRLAGRGMGLSIVLQ
SVRGLGGGARLGARRPYGAEVVVSAPLSLARQTVILIETGGGTFGLPSFGVVRLLRLAQDRLETVEGALTARIGIGEADV
VVPVVSMAAVLGNAESEIPASGGTVSAVLLSRGERHVAFAVDAFSDVREMAVEAAPGEGLDAPLALGVALLEGETPLMVL
DPDGLVDRWLRDERRLAAAGLGLASRAAERPRQRTVLVVDDSITTRTLEKSILEGQGYRVLLAVDGVDALHVLRSGEAIV
DVVVADVEMPRMDGFSLLQAVKADASLAALPVILMTSRNDPTDVRRGMDLGAEAYITKQKFDQRELLATIGRIL
>Mature_713_residues
ADIRAQLLAAFEVEHREHLEAIRRALTAPEQADLREVFRRAHSLKGAARAVDLPRIEELAHGLEDLIAGVGEGAGALDRP
TLDAIHLLLDRIEAEAEAARTGVPPDGPDQAPSEGEPPAEAAASAVEGEAGLEYVRIDAQALRELAQAAHQLANDVRAEQ
SAPQQLRRLHRESRRLEQLWSELRLRLGEGRDGARARDFEHALKTLTRDLADLGQTQHRTSWSLQTDLGVLREQVDRIAL
TPAATVFGDLGRMVRELARAEGVEVDVRVEGLDVRAERRVLQALRDPVIHLLRNALSHGAEPAEARRRAGKPEALAVGLQ
ISARGDRLQARVYDDGAGPDLARIEQAAIDRGLLPKRSPATPPPSPEEVLALAFEPGVSSAEAVDRLAGRGMGLSIVLQS
VRGLGGGARLGARRPYGAEVVVSAPLSLARQTVILIETGGGTFGLPSFGVVRLLRLAQDRLETVEGALTARIGIGEADVV
VPVVSMAAVLGNAESEIPASGGTVSAVLLSRGERHVAFAVDAFSDVREMAVEAAPGEGLDAPLALGVALLEGETPLMVLD
PDGLVDRWLRDERRLAAAGLGLASRAAERPRQRTVLVVDDSITTRTLEKSILEGQGYRVLLAVDGVDALHVLRSGEAIVD
VVVADVEMPRMDGFSLLQAVKADASLAALPVILMTSRNDPTDVRRGMDLGAEAYITKQKFDQRELLATIGRIL

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=294, Percent_Identity=30.952380952381, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790863, Length=111, Percent_Identity=34.2342342342342, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=36.9747899159664, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76399; Mature: 76268

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIRAQLLAAFEVEHREHLEAIRRALTAPEQADLREVFRRAHSLKGAARAVDLPRIEEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHCCCHHHHHH
AHGLEDLIAGVGEGAGALDRPTLDAIHLLLDRIEAEAEAARTGVPPDGPDQAPSEGEPPA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EAAASAVEGEAGLEYVRIDAQALRELAQAAHQLANDVRAEQSAPQQLRRLHRESRRLEQL
HHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
WSELRLRLGEGRDGARARDFEHALKTLTRDLADLGQTQHRTSWSLQTDLGVLREQVDRIA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHH
LTPAATVFGDLGRMVRELARAEGVEVDVRVEGLDVRAERRVLQALRDPVIHLLRNALSHG
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AEPAEARRRAGKPEALAVGLQISARGDRLQARVYDDGAGPDLARIEQAAIDRGLLPKRSP
CCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
ATPPPSPEEVLALAFEPGVSSAEAVDRLAGRGMGLSIVLQSVRGLGGGARLGARRPYGAE
CCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
VVVSAPLSLARQTVILIETGGGTFGLPSFGVVRLLRLAQDRLETVEGALTARIGIGEADV
EEEECCHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHH
VVPVVSMAAVLGNAESEIPASGGTVSAVLLSRGERHVAFAVDAFSDVREMAVEAAPGEGL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCC
DAPLALGVALLEGETPLMVLDPDGLVDRWLRDERRLAAAGLGLASRAAERPRQRTVLVVD
CCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEC
DSITTRTLEKSILEGQGYRVLLAVDGVDALHVLRSGEAIVDVVVADVEMPRMDGFSLLQA
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHH
VKADASLAALPVILMTSRNDPTDVRRGMDLGAEAYITKQKFDQRELLATIGRIL
HHCCCHHHHHHEEEEECCCCHHHHHHCCCCCCHHHEEHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
ADIRAQLLAAFEVEHREHLEAIRRALTAPEQADLREVFRRAHSLKGAARAVDLPRIEEL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHCCCHHHHHH
AHGLEDLIAGVGEGAGALDRPTLDAIHLLLDRIEAEAEAARTGVPPDGPDQAPSEGEPPA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EAAASAVEGEAGLEYVRIDAQALRELAQAAHQLANDVRAEQSAPQQLRRLHRESRRLEQL
HHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
WSELRLRLGEGRDGARARDFEHALKTLTRDLADLGQTQHRTSWSLQTDLGVLREQVDRIA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHH
LTPAATVFGDLGRMVRELARAEGVEVDVRVEGLDVRAERRVLQALRDPVIHLLRNALSHG
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AEPAEARRRAGKPEALAVGLQISARGDRLQARVYDDGAGPDLARIEQAAIDRGLLPKRSP
CCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
ATPPPSPEEVLALAFEPGVSSAEAVDRLAGRGMGLSIVLQSVRGLGGGARLGARRPYGAE
CCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
VVVSAPLSLARQTVILIETGGGTFGLPSFGVVRLLRLAQDRLETVEGALTARIGIGEADV
EEEECCHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHH
VVPVVSMAAVLGNAESEIPASGGTVSAVLLSRGERHVAFAVDAFSDVREMAVEAAPGEGL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCC
DAPLALGVALLEGETPLMVLDPDGLVDRWLRDERRLAAAGLGLASRAAERPRQRTVLVVD
CCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEC
DSITTRTLEKSILEGQGYRVLLAVDGVDALHVLRSGEAIVDVVVADVEMPRMDGFSLLQA
CCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHH
VKADASLAALPVILMTSRNDPTDVRRGMDLGAEAYITKQKFDQRELLATIGRIL
HHCCCHHHHHHEEEEECCCCHHHHHHCCCCCCHHHEEHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]