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The map label for this gene is tlpA [H]

Identifier: 197104159

GI number: 197104159

Start: 755836

End: 757491

Strand: Direct

Name: tlpA [H]

Synonym: PHZ_c0693

Alternate gene names: 197104159

Gene position: 755836-757491 (Clockwise)

Preceding gene: 197104158

Following gene: 197104160

Centisome position: 18.91

GC content: 71.07

Gene sequence:

>1656_bases
GTGACCATCGCCAACCGGATCCTCCTGGGCTTCGCCGCCGTCATCGTGCTGATGATCGCGGTGGGGCTGCTCGCGCTGAA
CCAGATCGGCGACATCCGCCGCGAGACGGAGACGATCATCACCCGGGACCTGGGCTTCGTGCGCCTGGTCAGCGAAATCC
GCGTCTCCCGCCAGCAGATGCAGGCCGCGGCCGAAACCGGGTTCAGCGACCGGATGGCCCGCCAGGCGGTCGGCGGCGGC
GAGGGCCCCGACTGGCGCGAGCGCAGCGCCGCGGTGGAACAGGCCCTGCAGCAGGCCCGGAGCCTGGCCGGGCAGTACGA
GAGCAACGCCCTGAGCGCCGACCGCCAGCAGGCGTGGCGGAAGGTCGGCGAGTCCCTCGCGGCGGCCGCCCCGATCCTGC
AGGCGTCCAAGACCGACAACGAAACCGTCGAAGCGGCGATCGCCCGCGGCGACTTCGCCGAGGCCGCCGACGTGCGCCAG
CGGCTGGCCGGCCGCCGGGGCGATTTCGAGCGCCAGATGCAGAGCATCCTGAAAGAGATGGACGGGGTGCTGGAGGCCGG
CCAGGCCCGGCTGACCGACGCCTACGAGCTGAGCCGCAACATCCTGCTGACGGGGCTGTTCATCGCCGTCCTGCTGGGGA
TCGGCGCCGCCTACTACATCCGCAACTCCATCGTCGGACCGCTGAGCGCGTTCATGGCGTTCGTGGAGCGGGTCGGGCAG
GGCGACCTGGCGGGCCAGACGGCGGCGACCTCCAAGGACGAGATCGGCCAGCTCGGCTCGACCCTCAACGCCATGGTGGA
CGGGTTGAAGGAGCTGGCGCGCCAGAGCCGCGACGCCACCGAGAACCTCAATGCGGCGACGGCGGAGATCCGCGCCTCGA
CCCAGGAGCAGGCGGCCGGGGTCGAGGAGCAGCTGGCCGCGGTGCAGGAGACCGCCGCCACGGTCGACGAGATCACCCAC
TCGGGGGCTCAGATCAGCAAGCGGGCCCAGGAGGTGATCGCCTCGGCCCAGGCGACCGCCCAGACCAGCACCGAGGGCCT
GCGGGCCGTGGACGAGACCACCCGAGCGATGGACGCCATCCGCGACCAGGCCGAGGCCGTGGCCGAGAACATCGTGGCGC
TGAGCGAGAAGACGCAGGCGATCGGCGACATCATCGCCACCGTCAACGACATCTCCGAGCGCTCGCACCTGCTGGCGCTG
AACGCCGCCATCGAGGCGGCCGCGGCGGGCGAGCACGGCCGCAGCTTCTCGGTGGTCGCCTCGGAGATGAAGATGCTGGC
CGACCAGGCCAAGGACGCCACCGGCCAGGTCCGCTCGATCCTGGGGGACATCCAGCGGGGCATCAACGCCTCGGTGATGC
TGACCGAGGAGGCGGTGAAGCGGGTCGCCGCCGGCAAGGAGCGCACCGACACCACCCACCGGACGATCACCGAGATCACC
GGCCGGGTGCAGGAGAGCGTGCAGACGTTCCAGCAGATCGTCGCCTCGACGAACCAGCAGCAACTCGGCATCGAGCAGGT
GATGAGCGCGCTGCAGAACATCCGGCAGGCCAGCCAGCAGACCGCCGCCGGCACGCGCCAGCTGGACGAGGCCGCCGCCA
ACCTGACGCGCCTCTCGCAACAGCTGCTCGCGCTCGCCGAACGCTACCGGCTCTAG

Upstream 100 bases:

>100_bases
ACCACGCCGACAAGATCCTCGTCATGCTCTCCGTCGAGGCGCTGCTGGCCCCGACCCACACGACTTCCCACCGCTCGACT
TCCAGTGGAGTCCACGCCCC

Downstream 100 bases:

>100_bases
GGCCTGGCCTTGGCCGACATCCGCGCCCAGCTGCTGGCCGCCTTCGAGGTCGAGCACCGCGAGCACCTCGAAGCGATCCG
TCGCGCCCTGACCGCGCCGG

Product: Methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTIANRILLGFAAVIVLMIAVGLLALNQIGDIRRETETIITRDLGFVRLVSEIRVSRQQMQAAAETGFSDRMARQAVGGG
EGPDWRERSAAVEQALQQARSLAGQYESNALSADRQQAWRKVGESLAAAAPILQASKTDNETVEAAIARGDFAEAADVRQ
RLAGRRGDFERQMQSILKEMDGVLEAGQARLTDAYELSRNILLTGLFIAVLLGIGAAYYIRNSIVGPLSAFMAFVERVGQ
GDLAGQTAATSKDEIGQLGSTLNAMVDGLKELARQSRDATENLNAATAEIRASTQEQAAGVEEQLAAVQETAATVDEITH
SGAQISKRAQEVIASAQATAQTSTEGLRAVDETTRAMDAIRDQAEAVAENIVALSEKTQAIGDIIATVNDISERSHLLAL
NAAIEAAAAGEHGRSFSVVASEMKMLADQAKDATGQVRSILGDIQRGINASVMLTEEAVKRVAAGKERTDTTHRTITEIT
GRVQESVQTFQQIVASTNQQQLGIEQVMSALQNIRQASQQTAAGTRQLDEAAANLTRLSQQLLALAERYRL

Sequences:

>Translated_551_residues
MTIANRILLGFAAVIVLMIAVGLLALNQIGDIRRETETIITRDLGFVRLVSEIRVSRQQMQAAAETGFSDRMARQAVGGG
EGPDWRERSAAVEQALQQARSLAGQYESNALSADRQQAWRKVGESLAAAAPILQASKTDNETVEAAIARGDFAEAADVRQ
RLAGRRGDFERQMQSILKEMDGVLEAGQARLTDAYELSRNILLTGLFIAVLLGIGAAYYIRNSIVGPLSAFMAFVERVGQ
GDLAGQTAATSKDEIGQLGSTLNAMVDGLKELARQSRDATENLNAATAEIRASTQEQAAGVEEQLAAVQETAATVDEITH
SGAQISKRAQEVIASAQATAQTSTEGLRAVDETTRAMDAIRDQAEAVAENIVALSEKTQAIGDIIATVNDISERSHLLAL
NAAIEAAAAGEHGRSFSVVASEMKMLADQAKDATGQVRSILGDIQRGINASVMLTEEAVKRVAAGKERTDTTHRTITEIT
GRVQESVQTFQQIVASTNQQQLGIEQVMSALQNIRQASQQTAAGTRQLDEAAANLTRLSQQLLALAERYRL
>Mature_550_residues
TIANRILLGFAAVIVLMIAVGLLALNQIGDIRRETETIITRDLGFVRLVSEIRVSRQQMQAAAETGFSDRMARQAVGGGE
GPDWRERSAAVEQALQQARSLAGQYESNALSADRQQAWRKVGESLAAAAPILQASKTDNETVEAAIARGDFAEAADVRQR
LAGRRGDFERQMQSILKEMDGVLEAGQARLTDAYELSRNILLTGLFIAVLLGIGAAYYIRNSIVGPLSAFMAFVERVGQG
DLAGQTAATSKDEIGQLGSTLNAMVDGLKELARQSRDATENLNAATAEIRASTQEQAAGVEEQLAAVQETAATVDEITHS
GAQISKRAQEVIASAQATAQTSTEGLRAVDETTRAMDAIRDQAEAVAENIVALSEKTQAIGDIIATVNDISERSHLLALN
AAIEAAAAGEHGRSFSVVASEMKMLADQAKDATGQVRSILGDIQRGINASVMLTEEAVKRVAAGKERTDTTHRTITEITG
RVQESVQTFQQIVASTNQQQLGIEQVMSALQNIRQASQQTAAGTRQLDEAAANLTRLSQQLLALAERYRL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=27.5324675324675, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI2367378, Length=435, Percent_Identity=27.3563218390805, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=26.9886363636364, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=27.4509803921569, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=268, Percent_Identity=28.3582089552239, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58953; Mature: 58822

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIANRILLGFAAVIVLMIAVGLLALNQIGDIRRETETIITRDLGFVRLVSEIRVSRQQM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAAETGFSDRMARQAVGGGEGPDWRERSAAVEQALQQARSLAGQYESNALSADRQQAWR
HHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KVGESLAAAAPILQASKTDNETVEAAIARGDFAEAADVRQRLAGRRGDFERQMQSILKEM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DGVLEAGQARLTDAYELSRNILLTGLFIAVLLGIGAAYYIRNSIVGPLSAFMAFVERVGQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDLAGQTAATSKDEIGQLGSTLNAMVDGLKELARQSRDATENLNAATAEIRASTQEQAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCC
VEEQLAAVQETAATVDEITHSGAQISKRAQEVIASAQATAQTSTEGLRAVDETTRAMDAI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQAEAVAENIVALSEKTQAIGDIIATVNDISERSHLLALNAAIEAAAAGEHGRSFSVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SEMKMLADQAKDATGQVRSILGDIQRGINASVMLTEEAVKRVAAGKERTDTTHRTITEIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHH
GRVQESVQTFQQIVASTNQQQLGIEQVMSALQNIRQASQQTAAGTRQLDEAAANLTRLSQ
HHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLALAERYRL
HHHHHHHHHCC
>Mature Secondary Structure 
TIANRILLGFAAVIVLMIAVGLLALNQIGDIRRETETIITRDLGFVRLVSEIRVSRQQM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAAAETGFSDRMARQAVGGGEGPDWRERSAAVEQALQQARSLAGQYESNALSADRQQAWR
HHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KVGESLAAAAPILQASKTDNETVEAAIARGDFAEAADVRQRLAGRRGDFERQMQSILKEM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DGVLEAGQARLTDAYELSRNILLTGLFIAVLLGIGAAYYIRNSIVGPLSAFMAFVERVGQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDLAGQTAATSKDEIGQLGSTLNAMVDGLKELARQSRDATENLNAATAEIRASTQEQAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCC
VEEQLAAVQETAATVDEITHSGAQISKRAQEVIASAQATAQTSTEGLRAVDETTRAMDAI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQAEAVAENIVALSEKTQAIGDIIATVNDISERSHLLALNAAIEAAAAGEHGRSFSVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SEMKMLADQAKDATGQVRSILGDIQRGINASVMLTEEAVKRVAAGKERTDTTHRTITEIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHH
GRVQESVQTFQQIVASTNQQQLGIEQVMSALQNIRQASQQTAAGTRQLDEAAANLTRLSQ
HHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLALAERYRL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]