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The map label for this gene is lnt [H]

Identifier: 194738278

GI number: 194738278

Start: 795052

End: 796641

Strand: Reverse

Name: lnt [H]

Synonym: SeSA_A0820

Alternate gene names: 194738278

Gene position: 796641-795052 (Counterclockwise)

Preceding gene: 194735556

Following gene: 194737342

Centisome position: 16.92

GC content: 54.47

Gene sequence:

>1590_bases
ATGACTCGCCCCAGCCAAAACTGGACGAATAACAGCAATAGTGGACTAAAAATGGCATTTGCCTCGTTAATTGAACGCCA
GCGTATTCGCCTGCTGCTGGCGTTATTATTCGGCGCCTGCGGAACACTGGCTTTCTCTCCGTATGACGTCTGGCCCGCAG
CGATAGTGTCGCTTATCGGGCTGCAGGCCTTAACGTTTAATCGCCGCCCGCTCCAGTCTGCCGCCATCGGCTATTGCTGG
GGACTCGGACTTTTCGGTAGCGGGATTAACTGGGTTTATGTCAGTATCGCGCAGTTTGGCGGCATGCCGGGCCCGGTTAA
CGTTTTTCTGGTGGTGCTGCTTGCAGCTTATCTCTCGCTGTATACCGGACTGTTTGCCGGGATTTTGTCGCGCCTGTGGC
CAAAAACCAACTGGCTGCGCGTCGCTATCGCCGCGCCTGCAGTATGGCAAATCACCGAATTTTTACGCGGCTGGGTGCTG
ACCGGCTTCCCCTGGCTGCAATTTGGCTATAGTCAGGTCGATGGCCCGCTAAAAGGCCTGGCGCCGGTAATGGGCGTCGA
AGCGATCAACTTCCTGCTGATGATGGTCAGCGGCCTGTTAGCGCTGGCACTGGCGACACGGAACTGGCGTCCGCTGGCTG
TCGCCGTGATTCTGTTTGCTTTGCCCTTTCCGCTACGTTATATCCAGTGGTTTACGCTGGAACCGGCCAAAGCGACCCAG
GTATCGCTGGTGCAGGGCGATATCCCGCAGTCGCTGAAGTGGGACGAAAACCAGCTACTGAATACGCTAAAAATTTATCT
CAACGAAACTCGCCCAGAGTTAGGCAAATCACAGATTATTATCTGGCCTGAGTCGGCGATTCCGGATCTCGAAATCAATC
AGCAGCCTTTCCTTCGTTCGCTGGACGAGATGTTACGCGAAAAAAATAGCACGCTGATCACCGGTATTGTCGATGCGCGT
CTCAATAAACAGAATCGATACGACACCTACAATACGATTATTACGTTGGGCAAGGATAATCCATACAGTTATGACTCGCC
CAATCGCTACAATAAAAATCACCTTGTGCCCTTTGGCGAGTTCGTTCCGCTGGAGTCTATCCTGCGTCCGCTGGCGCCGT
TCTTCGATCTGCCCATGTCCTCCTTTAGCCGCGGCCCTTATATCCAGCCGCAGTTACATGCGCACGACTATAAGCTGACG
GCGGCAATCTGTTATGAAATTATTCTTGGCGAACAGGTGCGGGATAACTTCCGCCCGGACACCGACTATCTGCTGACGAT
TTCTAACGACGCCTGGTTTGGTAAGTCCATTGGCCCGTGGCAACATTTCCAGATGGCGCGGATGCGTTCGCTGGAGCTGG
CGCGTCCGTTACTGCGCAGTACTAATAACGGTATTACGGCGGTGATTGGCCCGCAGGGCGAAATTCAGGCGATGATCCCG
CAGTTCACACGCCAGGTGCTGACCACCAAAGTCACGCCGACCACGGGGTTAACTCCCTATGCTCGTACCGGCAACTGGCC
GCTATGGGTACTGACCGCGCTGTTTGCTTTTGGCGCGGTAGTGATGAGTCTGCGACAACGACGGAAATAA

Upstream 100 bases:

>100_bases
TTACCGGCCCGCGGCGAAACCATTGACATTGATGGTTACCAGTTCAAAGTGGCGATGGCCGATAGTCGTCGTATTATTCA
GGTGCATGTCAGGATCCCGG

Downstream 100 bases:

>100_bases
TATCTCCCCAGGCCGGATAGCGCTTCATTTATCTGGCCTGAAAATCCTCCTTTTTCCCCCATTCTGGCACGTCTATTGCT
TTGTTAAACATGGCAAACCT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase; Copper homeostasis protein CutE [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MTRPSQNWTNNSNSGLKMAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCW
GLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAVWQITEFLRGWVL
TGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQ
VSLVQGDIPQSLKWDENQLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDAR
LNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLT
AAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIP
QFTRQVLTTKVTPTTGLTPYARTGNWPLWVLTALFAFGAVVMSLRQRRK

Sequences:

>Translated_529_residues
MTRPSQNWTNNSNSGLKMAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCW
GLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAVWQITEFLRGWVL
TGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQ
VSLVQGDIPQSLKWDENQLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDAR
LNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLT
AAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIP
QFTRQVLTTKVTPTTGLTPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
>Mature_528_residues
TRPSQNWTNNSNSGLKMAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWG
LGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAVWQITEFLRGWVLT
GFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQV
SLVQGDIPQSLKWDENQLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARL
NKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTA
AICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQ
FTRQVLTTKVTPTTGLTPYARTGNWPLWVLTALFAFGAVVMSLRQRRK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=512, Percent_Identity=89.0625, Blast_Score=939, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59516; Mature: 59385

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPSQNWTNNSNSGLKMAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHH
YTGLFAGILSRLWPKTNWLRVAIAAPAVWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGL
HHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHH
APVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCE
VSLVQGDIPQSLKWDENQLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRS
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHH
LDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGE
HHHHHHHCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
FVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPD
CCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIP
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
QFTRQVLTTKVTPTTGLTPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRPSQNWTNNSNSGLKMAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSL
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHH
YTGLFAGILSRLWPKTNWLRVAIAAPAVWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGL
HHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHH
APVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCE
VSLVQGDIPQSLKWDENQLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRS
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHH
LDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGE
HHHHHHHCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
FVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPD
CCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIP
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHH
QFTRQVLTTKVTPTTGLTPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]