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The map label for this gene is corC [H]

Identifier: 194735556

GI number: 194735556

Start: 796610

End: 797488

Strand: Reverse

Name: corC [H]

Synonym: SeSA_A0821

Alternate gene names: 194735556

Gene position: 797488-796610 (Counterclockwise)

Preceding gene: 194734762

Following gene: 194738278

Centisome position: 16.94

GC content: 52.45

Gene sequence:

>879_bases
ATGAGCGACGACAATTCACACAGTAGTGACACAGTAAACAGTAAAAAGGGATTTTTTTCCCTGCTACTCAGCCAGCTTTT
CCACGGGGAACCTAAAAACCGTGATGAGTTGCTGGCGCTGATCCGTGATTCCGGGCAGAACGAGCTTATCGATGAAGATA
CGCGCGATATGCTCGAAGGCGTAATGGACATCGCCGACCAGCGCGTTCGCGATATTATGATCCCGCGCTCCCAGATGATT
ACCCTGAAACGCAACCAGACGCTGGACGAATGTCTCGATGTTATCATCGAGTCCGCCCACTCGCGTTTTCCGGTGATCAG
CGAAGATAAAGATCACATTGAAGGGATTCTGATGGCCAAAGATTTGCTGCCGTTTATGCGCAGCGATGCCGAAGCCTTCA
GCATGGACAAAGTGTTACGCCCCGCGGTTGTCGTACCGGAAAGCAAACGGGTTGACCGTATGCTCAAGGAGTTCCGCTCC
CAGCGCTACCATATGGCCATCGTTATCGATGAGTTTGGCGGCGTTTCCGGCCTTGTGACTATCGAAGACATCCTCGAACT
GATTGTCGGTGAAATTGAAGATGAGTATGACGAAGAAGACGATATCGACTTCCGTCAGCTTAGCCGCCATACCTGGACGA
TTCGTGCGCTGGCGTCGATTGAAGACTTCAACGACGCTTTCGGCACCCACTTCAGCGATGAAGAGGTCGATACCATCGGC
GGGCTGGTGATGCAGGCGTTCGGCCATTTACCGGCCCGCGGCGAAACCATTGACATTGATGGTTACCAGTTCAAAGTGGC
GATGGCCGATAGTCGTCGTATTATTCAGGTGCATGTCAGGATCCCGGATGACTCGCCCCAGCCAAAACTGGACGAATAA

Upstream 100 bases:

>100_bases
GGCCTGATAAGCGTAGCGCCATCAGGCAAAACATGCCGTCACAGCTGAGTATACGCATGACGAGCTTTGTATTAACTAAC
ATGAGAACCCATACGACGCC

Downstream 100 bases:

>100_bases
CAGCAATAGTGGACTAAAAATGGCATTTGCCTCGTTAATTGAACGCCAGCGTATTCGCCTGCTGCTGGCGTTATTATTCG
GCGCCTGCGGAACACTGGCT

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNELIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRPAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALASIEDFNDAFGTHFSDEEVDTIG
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVRIPDDSPQPKLDE

Sequences:

>Translated_292_residues
MSDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNELIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRPAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALASIEDFNDAFGTHFSDEEVDTIG
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVRIPDDSPQPKLDE
>Mature_291_residues
SDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNELIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT
LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRPAVVVPESKRVDRMLKEFRSQ
RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALASIEDFNDAFGTHFSDEEVDTIGG
LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVRIPDDSPQPKLDE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=32.0388349514563, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI94681046, Length=184, Percent_Identity=30.9782608695652, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40068053, Length=188, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40068055, Length=188, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=97.2602739726027, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI1788119, Length=225, Percent_Identity=32, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=27.6, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693175, Length=250, Percent_Identity=26.8, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790664, Length=248, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33296; Mature: 33165

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNELIDEDTRDMLEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRSDAEAFSMDKVLRPAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALASIEDFNDAFGTHFSDEEVDTIG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVRIPDDSPQPKLDE
HHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNELIDEDTRDMLEG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRSDAEAFSMDKVLRPAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALASIEDFNDAFGTHFSDEEVDTIG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVRIPDDSPQPKLDE
HHHHHHHCCCCCCCCEEECCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]