| Definition | Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 chromosome, complete genome. |
|---|---|
| Accession | NC_011094 |
| Length | 4,709,075 |
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The map label for this gene is dxr [H]
Identifier: 194737994
GI number: 194737994
Start: 260179
End: 261462
Strand: Direct
Name: dxr [H]
Synonym: SeSA_A0245
Alternate gene names: 194737994
Gene position: 260179-261462 (Clockwise)
Preceding gene: 194737420
Following gene: 194736697
Centisome position: 5.53
GC content: 55.14
Gene sequence:
>1284_bases GTGTACAAAGCGCCGCGCAGAAGACATTATCAGGTCTCCTGTGCGGCGTTTTGCTTTTTATTCCGTTTCAACACTTCTGG ACGTTTCATGAAGCAATTAACCATTCTGGGCTCGACCGGCTCTATTGGTTGCAGCACACTGGACGTAGTGCGCCATAATC CTGATAGCTTCCGCGTTATCGCGCTGGTGGCGGGTAAAAATGTCGCCCGCATGGCGGAGCAGTGCCTGGAATTCTCGCCG CGTTATGCCGTGATGGACGATACGTTGAGCGCAGAACAGCTCAAAATAATGCTTCAGCAGCATGGCAGCCGCACCGAGGT TCTGAGCGGTCAGCAGGCTGCCTGTGAGATGGCGGCGCTTGATGAGGTCGGGCATGTGATGGCGGCCATTGTGGGCGCGG CTGGTTTACTGCCGACCCTGGCGGCGATTCGCGCAGGGAAGACGATTCTGCTGGCGAATAAAGAATCGCTGGTGACCTGC GGGCGGCTGTTTATGGACGAAGTAAAACGCAGCAACGCCCGGCTTTTACCCGTCGATAGCGAACATAACGCGATTTTTCA GAGTTTGCCGCAATCTATTCAGCATAATCTGGGATACGCTGACCTTGAGCAAAATGGTGTAACGTCGATTTTGCTTACCG GGTCTGGTGGCCCGTTTCGTGAAACGCCAATGTGCGATCTGGCAGCGATGACGCCGGATCAGGCATGTCGTCATCCGAAC TGGTCGATGGGGCGGAAAATCTCCGTCGACTCCGCCACCATGATGAATAAAGGTCTGGAATACATTGAAGCGCGTTGGTT ATTTAATGCCAGCGCACGTCAGATGGAAGTGTTGATCCATCCGCAATCGGTCATTCATTCGATGGTGCGTTATCAGGACG GCAGCGTCCTGGCGCAGCTTGGAGAACCTGACATGCGTACGCCTATTGCGCATACGATGGCATGGCCGAATCGCGTCGCG TCCGGCGCGCAGCCGCTCGATTTTTGCAAACTCAGCGCGCTGACGTTTAGCGCGCCAGATTATCAGCGTTATCCATGCCT GAAGCTGGCGATGGAGGCGTTTGAGCAAGGTCAGGCGGCAACGACGGCGCTCAATGCGGCAAACGAAATCACCGTTGCCG CGTTTCTGGCGCAACAGATTCGTTTTACCGATATCGCCGGGCTCAATTTAGCGGTGCTGGAGAGGATGGATTTACAGGAA CCGGCAAGCGTTGAGGACGTATTGCAGGTTGACGCCATCGCGCGTGAAGTAGCCAGAAAACAAGTGATACGGCTCTCACG CTGA
Upstream 100 bases:
>100_bases GGATGCGGCGTTGGCAGATAAAGAAGCAGAACTGATGCAGTTCTGATTGATCTGTACGCAGATATAAACTCATTCCACCG CTAAACCTGGCGGATGAGTG
Downstream 100 bases:
>100_bases CGATTATCCCGCGACAGAAGATCGTGCTATTTGTTAGCGTTGGGCTTCGGTGATATAGTCTGCGCCACCTGATCGCAGGT TTTTGGCTTTTTTCGGTCAG
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase [H]
Number of amino acids: Translated: 427; Mature: 427
Protein sequence:
>427_residues MYKAPRRRHYQVSCAAFCFLFRFNTSGRFMKQLTILGSTGSIGCSTLDVVRHNPDSFRVIALVAGKNVARMAEQCLEFSP RYAVMDDTLSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTC GRLFMDEVKRSNARLLPVDSEHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPN WSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVA SGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQE PASVEDVLQVDAIAREVARKQVIRLSR
Sequences:
>Translated_427_residues MYKAPRRRHYQVSCAAFCFLFRFNTSGRFMKQLTILGSTGSIGCSTLDVVRHNPDSFRVIALVAGKNVARMAEQCLEFSP RYAVMDDTLSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTC GRLFMDEVKRSNARLLPVDSEHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPN WSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVA SGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQE PASVEDVLQVDAIAREVARKQVIRLSR >Mature_427_residues MYKAPRRRHYQVSCAAFCFLFRFNTSGRFMKQLTILGSTGSIGCSTLDVVRHNPDSFRVIALVAGKNVARMAEQCLEFSP RYAVMDDTLSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTC GRLFMDEVKRSNARLLPVDSEHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPN WSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVA SGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQE PASVEDVLQVDAIAREVARKQVIRLSR
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [H]
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family [H]
Homologues:
Organism=Escherichia coli, GI1786369, Length=397, Percent_Identity=88.9168765743073, Blast_Score=713, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 [H]
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom [H]
EC number: =1.1.1.267 [H]
Molecular weight: Translated: 46893; Mature: 46893
Theoretical pI: Translated: 7.48; Mature: 7.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.3 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 6.8 %Cys+Met (Translated Protein) 2.3 %Cys (Mature Protein) 4.4 %Met (Mature Protein) 6.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYKAPRRRHYQVSCAAFCFLFRFNTSGRFMKQLTILGSTGSIGCSTLDVVRHNPDSFRVI CCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEHEEEECCCCCCCCCCHHHHHCCCCCEEEE ALVAGKNVARMAEQCLEFSPRYAVMDDTLSAEQLKIMLQQHGSRTEVLSGQQAACEMAAL EEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHH DEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDEVKRSNARLLPVDS HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCC EHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPN CHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCHHHHCCCC WSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQL CCCCCEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHCCCCCCEEEC GEPDMRTPIAHTMAWPNRVASGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAA CCCCCCCCHHHHHCCCHHHCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCHH TTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQEPASVEDVLQVDAIAREVARK HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH QVIRLSR HHHHCCC >Mature Secondary Structure MYKAPRRRHYQVSCAAFCFLFRFNTSGRFMKQLTILGSTGSIGCSTLDVVRHNPDSFRVI CCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEHEEEECCCCCCCCCCHHHHHCCCCCEEEE ALVAGKNVARMAEQCLEFSPRYAVMDDTLSAEQLKIMLQQHGSRTEVLSGQQAACEMAAL EEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHH DEVGHVMAAIVGAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDEVKRSNARLLPVDS HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCC EHNAIFQSLPQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPN CHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCHHHHCCCC WSMGRKISVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQL CCCCCEEECCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHCCCCCCEEEC GEPDMRTPIAHTMAWPNRVASGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAA CCCCCCCCHHHHHCCCHHHCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCHH TTALNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLQEPASVEDVLQVDAIAREVARK HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH QVIRLSR HHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA