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The map label for this gene is nikD [H]

Identifier: 194737552

GI number: 194737552

Start: 1309192

End: 1309989

Strand: Direct

Name: nikD [H]

Synonym: SeSA_A1348

Alternate gene names: 194737552

Gene position: 1309192-1309989 (Clockwise)

Preceding gene: 194736779

Following gene: 194736579

Centisome position: 27.8

GC content: 54.51

Gene sequence:

>798_bases
ATGCTGAGTTTTCAACAGGTTACGCTGGAAAACGCGCGTTATCGCTGGTATGGCGCGAGACGCTGGTCGCCGTTATTACA
GAATGTCTCTTTTGATATCGCGCCCGGAGAAATGGTGGCATTGGTTGGCGGCAGCGGGGAGGGCAAAAGTCTGCTGCTGC
AATGCCTGCTCGATCTGCTGCCGGAAAATTTACGCTTTCGGGGGGAAATTACGCTTGATGGCAACCGGCTGGACAGACAT
ACCATCAGGCAGCTTAGGGGCAATACGTTTAGCTACGTGCCGCAGGGGGTACAGGCGCTTAATCCCATGCTGAATATCAG
AAAACATTTGAACAGAGCATGTCATCTGACCGGACGCGTCTGGGATGAGACGCAGATGGTACAGCTATTGCAGCAAAGCG
ATCTCGAACCGACAGTCCTGGAACGCTTTCCTCGCCAGCTCTCCGGCGGGATGGCTAAACGAATTCTGGCGTGCCACGCC
TCGCTCAGCCAGGCACGTTATATCCTCGCGGATGAGATCACCGCCTGGCTTGATACCGCACTGGCAAACCAGTTGCTTGA
GCACTTGCGAGGTCTCTGCGAGCGGGGATGCGGCGTGCTGTGGGTGACTCATGACCTGCTGCTGGCGGCGCGGTATGCCG
ATCGCATTGTGGCGCTGCATCAGGGTTATATCACGGACAATATTCGCTGTGAACGATTACAGCCGGAAGAGATGAGTGAG
CCGTTAAAACGACAATGGCAAGCATTGCCTGAACTAAACCCGTTATTTATGCCGACCAGAGAGGGAATAGAATGCTAA

Upstream 100 bases:

>100_bases
GGTGGCTGGTGCTGTTTCCCGGCCTAATGTTATTCACGCTGGTGATGCTCTTCGATCAGTTTGCGCGCGCCATTCAGCGG
CTGTGGCTAAGGAGTGACGT

Downstream 100 bases:

>100_bases
GCTGCCGCGACCTCGTTATTCGTCAGGGTGGGAAAGTCTTATGGCAGAACCTGACGTTTACGATTTCTGCCGGTGAACGG
GTAGGAATTCATGCGCCAAG

Product: nickel/di-oligopepetide ABC transporter ATP binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLSFQQVTLENARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRVWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTREGIEC

Sequences:

>Translated_265_residues
MLSFQQVTLENARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRVWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTREGIEC
>Mature_265_residues
MLSFQQVTLENARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRVWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
PLKRQWQALPELNPLFMPTREGIEC

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI90421313, Length=165, Percent_Identity=32.1212121212121, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI9955963, Length=247, Percent_Identity=29.1497975708502, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI42741659, Length=224, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789890, Length=233, Percent_Identity=31.7596566523605, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693107, Length=244, Percent_Identity=27.4590163934426, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788506, Length=231, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787105, Length=252, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=28.8135593220339, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=30.5936073059361, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787759, Length=218, Percent_Identity=29.8165137614679, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI48994883, Length=210, Percent_Identity=28.0952380952381, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=31.3636363636364, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789963, Length=216, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=28.2700421940928, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788225, Length=250, Percent_Identity=28.4, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994997, Length=219, Percent_Identity=27.3972602739726, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790544, Length=216, Percent_Identity=32.4074074074074, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786872, Length=229, Percent_Identity=28.82096069869, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789991, Length=239, Percent_Identity=21.7573221757322, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=33.1730769230769, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787547, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790467, Length=208, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787548, Length=241, Percent_Identity=24.4813278008299, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786398, Length=228, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788472, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081709, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789962, Length=250, Percent_Identity=24.8, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787758, Length=220, Percent_Identity=25.9090909090909, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI48995001, Length=247, Percent_Identity=27.5303643724696, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790739, Length=254, Percent_Identity=27.5590551181102, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789032, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787500, Length=209, Percent_Identity=23.444976076555, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786345, Length=205, Percent_Identity=30.2439024390244, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=209, Percent_Identity=31.1004784688995, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17552010, Length=199, Percent_Identity=29.6482412060301, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=235, Percent_Identity=27.2340425531915, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015857
- InterPro:   IPR003593
- InterPro:   IPR014138 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 30294; Mature: 30294

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFQQVTLENARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCCHHHHHHCCEEEEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRV
CCCCEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
PLKRQWQALPELNPLFMPTREGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSFQQVTLENARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCCHHHHHHCCEEEEECCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRV
CCCCEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCERLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHH
PLKRQWQALPELNPLFMPTREGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]