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The map label for this gene is nikC [C]

Identifier: 194736779

GI number: 194736779

Start: 1308386

End: 1309198

Strand: Direct

Name: nikC [C]

Synonym: SeSA_A1347

Alternate gene names: 194736779

Gene position: 1308386-1309198 (Clockwise)

Preceding gene: 194736299

Following gene: 194737552

Centisome position: 27.78

GC content: 56.7

Gene sequence:

>813_bases
ATGCTCTATAATCCTGCCCCAACGTTGCTTCGTCTGATCCTCTCCGTTACCTGTCTGCTGTTTATTGCTGGATACGGTTA
TGCCACGTTGAGCCAGCCGCCAGAGGTTAATCTGCTTGCCCGGCATCTGTCGCCTGATATCCAGCACTGGTTTGGCACCG
ATAATCTGGGGCGTGATGTATGGCTGCGTTGCTTTCAGGGGGCCTTCACCAGTTTACAAATTGGCGTTGGCGCCGCGCTG
TGCAGCGGCGTTATCGCGCTAGTGATGGCGGCAGCGGCGCGCATTCATCCCCGGCTGGACCTCCTGATGCGGCTGATAAC
CGATGCCATGCTCGCCATGCCGCATTTACTTTTGCTGATCCTTATCTGTTTTACGCTCGGCGGCGGTAAAAGCGGCGTCA
TTGCGGCCGTGGCGTTAACGCACTGGCCCCGTCTGGCGCTGATTCTGCGCGCCGACGCGGAGCGGGTAGCGCAGAGTGAC
TACCTGACATTGACCTATCGTCTGGGGCATGGACACCTTTATTGCTGGCGATATCACTATTTTCCGGCGCTATTGCCGCA
ATGGTTGACGGGAACGTTATTGATGTTTCCTCATGCGGTATTGCACAGCGCGGCGTTAAGTTTTCTGGGGTTTGGGCTGG
CGCCGCATGAGCCTTCGCTGGGGCTGTTGCTGGCGGATGCGTTACGGTTTATTAGCCATGGAAACTGGTGGCTGGTGCTG
TTTCCCGGCCTAATGTTATTCACGCTGGTGATGCTCTTCGATCAGTTTGCGCGCGCCATTCAGCGGCTGTGGCTAAGGAG
TGACGTATGCTGA

Upstream 100 bases:

>100_bases
CTCATGGGGATCGTTTTATTCTGTACGCTATTAGTGTTTGCCGGAAATACGATTTCAGCCTGGCTTGTGGTGGTGCTTAA
TCGATCGCTGGAGCGTCCCG

Downstream 100 bases:

>100_bases
GTTTTCAACAGGTTACGCTGGAAAACGCGCGTTATCGCTGGTATGGCGCGAGACGCTGGTCGCCGTTATTACAGAATGTC
TCTTTTGATATCGCGCCCGG

Product: nickel/di-oligopepetide ABC transporter permease subunit

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLYNPAPTLLRLILSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAAARIHPRLDLLMRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC

Sequences:

>Translated_270_residues
MLYNPAPTLLRLILSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAAARIHPRLDLLMRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
>Mature_270_residues
MLYNPAPTLLRLILSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAAL
CSGVIALVMAAAARIHPRLDLLMRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=30.6382978723404, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787054, Length=214, Percent_Identity=29.9065420560748, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787760, Length=264, Percent_Identity=26.1363636363636, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789964, Length=211, Percent_Identity=34.1232227488152, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787549, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788505, Length=185, Percent_Identity=30.8108108108108, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30037; Mature: 30037

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYNPAPTLLRLILSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCHHH
WLRCFQGAFTSLQIGVGAALCSGVIALVMAAAARIHPRLDLLMRLITDAMLAMPHLLLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSDYLTLTYRLGHGHLYCWRYHY
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEHHH
FPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEHH
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYNPAPTLLRLILSVTCLLFIAGYGYATLSQPPEVNLLARHLSPDIQHWFGTDNLGRDV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCHHH
WLRCFQGAFTSLQIGVGAALCSGVIALVMAAAARIHPRLDLLMRLITDAMLAMPHLLLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
LICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSDYLTLTYRLGHGHLYCWRYHY
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEHHH
FPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEPSLGLLLADALRFISHGNWWLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEHH
FPGLMLFTLVMLFDQFARAIQRLWLRSDVC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA