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The map label for this gene is ycbL [H]

Identifier: 194737484

GI number: 194737484

Start: 1096210

End: 1096857

Strand: Direct

Name: ycbL [H]

Synonym: SeSA_A1112

Alternate gene names: 194737484

Gene position: 1096210-1096857 (Clockwise)

Preceding gene: 194734847

Following gene: 194738134

Centisome position: 23.28

GC content: 55.25

Gene sequence:

>648_bases
ATGAACTATCGTATTATTCCGGTCACCGCGTTCTCCCAGAACTGTTCATTAATCTGGTGCGAACAAACCCGGCTGGCGGC
GCTGGTCGATCCGGGCGGCGACGCGGAAAAAATTAAACAGGAAGTGGACGCCAGCGGCGTGACGTTGATGCAAATTTTAC
TCACGCATGGGCATCTCGATCATGTCGGCGCGGCGAGTGAACTGGCGCAGCATTACGGCGTTCCTGTTATCGGTCCGGAA
AAAGAAGATGAGTTCTGGCTGCAAGGACTGCCGGCGCAAAGCCGCATGTTTGGTCTGGATGAGTGTCAGCCGCTGACGCC
TGATCGCTGGTTGAACGACGGCGATCGCGTCAGCGTGGGGAATGTGACGTTACAGGTGTTACATTGTCCGGGACACACGC
CGGGACACGTGGTTTTCTTTGATGAACAGTCGCAACTGCTGATCTCCGGCGATGTGATTTTCAAAGGTGGCGTCGGGCGC
AGCGATTTTCCTCGCGGCGATCACACCCAGTTGATTGACGCTATTAAGCGTAAATTATTGCCGCTTGGCGATGATGTGAC
CTTTATTCCTGGCCACGGCCCGCTCTCTACGCTCGGGTACGAGCGTCTGCATAATCCCTTCCTGCAAGATGAGATGCCGG
TCTGGTAA

Upstream 100 bases:

>100_bases
CGCAGGTGGTGTAGGATATTACCCACGTAGTAACTTTGTGCATATTGATACCGGGCCGGCGCGGCACTGGTAATCAGCGA
GGCTTAATCAAAGGAGCAGT

Downstream 100 bases:

>100_bases
GCAGAATGAAAAAGCCTGCAATGTGCAGGCTTTTTTATCGGTCACGCCAGTCGGCAGCTTTTTACAGTACCGCGACAATG
GCTTCGCACAGCGGCGCCAT

Product: hydroxyacylglutathione hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Sequences:

>Translated_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
>Mature_215_residues
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPE
KEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI116642887, Length=196, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI41327741, Length=203, Percent_Identity=28.0788177339901, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=91.6279069767442, Blast_Score=414, Evalue=1e-117,
Organism=Drosophila melanogaster, GI221330176, Length=192, Percent_Identity=25.5208333333333, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23737; Mature: 23737

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
HVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVG
CCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKRKLL
CEEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGVTLMQILLTHGHLD
CCEEEEEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC
HVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDECQPLTPDRWLNDGDRVSVG
CCCCHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCHHCCCCCCEEEEC
NVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGRSDFPRGDHTQLIDAIKRKLL
CEEEEEEECCCCCCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]